Inactivating mutations in GNA13 and RHOA in Burkitt’s lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells

GIV/Girdin Transmits Signals from Multiple Receptors by Triggering Trimeric G Protein Activation

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Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine

(2015) L. Qin et al.   SCIENCE

The RHOA G17V gene mutation occurs frequently in peripheral T-cell lymphoma and is associated with a characteristic molecular signature

(2014) R. Manso et al.   BLOOD

Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry

(2014) Xiaodong Feng et al.   CANCER CELL

RecurrentRHOAmutations in pediatric Burkitt lymphoma treated according to the NHL-BFM protocols

(2014) Marius Rohde et al.   GENES CHROMOSOMES & CANCER

mTOR Co-Targeting in Cetuximab Resistance in Head and Neck Cancers Harboring PIK3CA and RAS Mutations

(2014) Zhiyong Wang et al.   JNCI-Journal of the National Cancer Institute

Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma

(2014) Jagan R. Muppidi et al.   NATURE

A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T cell lymphoma

(2014) Hae Yong Yoo et al.   NATURE GENETICS

Somatic RHOA mutation in angioimmunoblastic T cell lymphoma

(2014) Mamiko Sakata-Yanagimoto et al.   NATURE GENETICS

RHOA mutations in peripheral T cell lymphoma

(2014) Jan Cools   NATURE GENETICS

Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas

(2014) Teresa Palomero et al.   NATURE GENETICS

PDZ-RhoGEF and LARG Are Essential for Embryonic Development and Provide a Link between Thrombin and LPA Receptors and Rho Activation

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MicroRNA-182 and MicroRNA-200a Control G-protein Subunit α-13 (GNA13) Expression and Cell Invasion Synergistically in Prostate Cancer Cells

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Diffuse large B-cell lymphoma—treatment approaches in the molecular era

(2013) Mark Roschewski et al.   Nature Reviews Clinical Oncology

The Histological and Biological Spectrum of Diffuse Large B-Cell Lymphoma in the World Health Organization Classification

(2012) Madhu P. Menon et al.   CANCER JOURNAL

The genetic landscape of mutations in Burkitt lymphoma

(2012) Cassandra Love et al.   NATURE GENETICS

TGFα shedding assay: an accurate and versatile method for detecting GPCR activation

(2012) Asuka Inoue et al.   NATURE METHODS

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

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LPA-producing enzyme PA-PLA1α regulates hair follicle development by modulating EGFR signalling

(2011) Asuka Inoue et al.   EMBO JOURNAL

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

(2011) Ryan D. Morin et al.   NATURE

The sphingosine 1-phosphate receptor S1P2 maintains the homeostasis of germinal center B cells and promotes niche confinement

(2011) Jesse A Green et al.   NATURE IMMUNOLOGY

A Synthetic Biology Approach Reveals a CXCR4-G13-Rho Signaling Axis Driving Transendothelial Migration of Metastatic Breast Cancer Cells

(2011) H. Yagi et al.   Science Signaling

Status of GPCR Modeling and Docking as Reflected by Community-wide GPCR Dock 2010 Assessment

(2011) Irina Kufareva et al.   STRUCTURE

Aggressive B-Cell Lymphomas: A Review of New and Old Entities in the WHO Classification

(2011) E. S. Jaffe et al.   Hematology-American Society of Hematology Education Program

Mutations inGNA11in Uveal Melanoma

(2010) Catherine D. Van Raamsdonk et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of G12 proteins in oncogenesis and metastasis

(2009) Juhi Juneja et al.   BRITISH JOURNAL OF PHARMACOLOGY

Targeted Disruption of the S1P2 Sphingosine 1-Phosphate Receptor Gene Leads to Diffuse Large B-Cell Lymphoma Formation

(2009) G. Cattoretti et al.   CANCER RESEARCH

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi

(2008) Catherine D. Van Raamsdonk et al.   NATURE