Nonmuscle myosin IIA and IIB differentially modulate migration and alter gene expression in primary mouse tumorigenic cells

Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment

(2019) Mirella Georgouli et al.   CELL

Mammalian nonmuscle myosin II comes in three flavors

(2018) Maria S. Shutova et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MYH9: Structure, functions and role of non-muscle myosin IIA in human disease

(2018) Alessandro Pecci et al.   GENE

Mechanotransduction via the LINC complex regulates DNA replication in myonuclei

(2018) Shuoshuo Wang et al.   JOURNAL OF CELL BIOLOGY

Emerging views of the nucleus as a cellular mechanosensor

(2018) Tyler J. Kirby et al.   NATURE CELL BIOLOGY

Myosin IIA interacts with the spectrin-actin membrane skeleton to control red blood cell membrane curvature and deformability

(2018) Alyson S. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p63-dependent Dickkopf3 expression promotes esophageal cancer cell proliferation via CKAP4

(2018) Chihiro Kajiwara et al.   CANCER RESEARCH

PCB exposure and potential future cancer incidence in Slovak children: an assessment from molecular finger printing by Ingenuity Pathway Analysis (IPA®) derived from experimental and epidemiological investigations

(2017) Somiranjan Ghosh et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

UNC-45a promotes myosin folding and stress fiber assembly

(2017) Jaakko I. Lehtimäki et al.   JOURNAL OF CELL BIOLOGY

The serine protease inhibitor serpinB2 binds and stabilizes p21 in senescent cells

(2017) Hsi-Hsien Hsieh et al.   JOURNAL OF CELL SCIENCE

Systematic identification of cancer-related long noncoding RNAs and aberrant alternative splicing of quintuple-negative lung adenocarcinoma through RNA-Seq

(2017) Lu Zhang et al.   LUNG CANCER

Activation of ROCK and MLCK tunes regional stress fiber formation and mechanics via preferential myosin light chain phosphorylation

(2017) Elena Kassianidou et al.   MOLECULAR BIOLOGY OF THE CELL

Differential role of nonmuscle myosin II isoforms during blebbing of MCF-7 cells

(2017) Sumit K. Dey et al.   MOLECULAR BIOLOGY OF THE CELL

Actin dynamics and competition for myosin monomer govern the sequential amplification of myosin filaments

(2017) Jordan R. Beach et al.   NATURE CELL BIOLOGY

The assembly and function of perinuclear actin cap in migrating cells

(2017) Miloslava Maninova et al.   PROTOPLASMA

Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness

(2017) Michiru Nishita et al.   Scientific Reports

Mechanotransduction and nuclear function

(2016) David M Graham et al.   CURRENT OPINION IN CELL BIOLOGY

Dorsal stress fibers, transverse actin arcs, and perinuclear actin fibers form an interconnected network that induces nuclear movement in polarizing fibroblasts

(2016) Miloslava Maninová et al.   FEBS Journal

Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment

(2016) Huy Quang Le et al.   NATURE CELL BIOLOGY

Transcription upregulation via force-induced direct stretching of chromatin

(2016) Arash Tajik et al.   NATURE MATERIALS

Constitutive Activation of Myosin-Dependent Contractility Sensitizes Glioma Tumor-Initiating Cells to Mechanical Inputs and Reduces Tissue Invasion

(2015) S. Y. Wong et al.   CANCER RESEARCH

Myosin 18A Coassembles with Nonmuscle Myosin 2 to Form Mixed Bipolar Filaments

(2015) Neil Billington et al.   CURRENT BIOLOGY

Non-muscle myosin II in disease: mechanisms and therapeutic opportunities

(2015) K. A. Newell-Litwa et al.   Disease Models & Mechanisms

Transcriptional profiling and biological pathway analysis of human equivalence PCB exposure in vitro: Indicator of disease and disorder development in humans

(2015) Somiranjan Ghosh et al.   ENVIRONMENTAL RESEARCH

Accessorizing and anchoring the LINC complex for multifunctionality

(2015) Wakam Chang et al.   JOURNAL OF CELL BIOLOGY

Mechanical stimulation induces formin-dependent assembly of a perinuclear actin rim

(2015) Xiaowei Shao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conditional deletion of nonmuscle myosin II-A in mouse tongue epithelium results in squamous cell carcinoma

(2015) Mary Anne Conti et al.   Scientific Reports

Phosphorylation of Nonmuscle myosin II-A regulatory light chain resists Sendai virus fusion with host cells

(2015) Provas Das et al.   Scientific Reports

Regulation of Nonmuscle Myosin II by Tropomyosin

(2014) Bipasha Barua et al.   BIOCHEMISTRY

BRCA2 Phosphorylated by PLK1 Moves to the Midbody to Regulate Cytokinesis Mediated by Nonmuscle Myosin IIC

(2014) M. Takaoka et al.   CANCER RESEARCH

Sizing and shaping the nucleus: mechanisms and significance

(2014) Predrag Jevtić et al.   CURRENT OPINION IN CELL BIOLOGY

Quantitative and unbiased analysis of directional persistence in cell migration

(2014) Roman Gorelik et al.   Nature Protocols

FibrilTool, an ImageJ plug-in to quantify fibrillar structures in raw microscopy images

(2014) Arezki Boudaoud et al.   Nature Protocols

Direct in Vivo RNAi Screen Unveils Myosin IIa as a Tumor Suppressor of Squamous Cell Carcinomas

(2014) D. Schramek et al.   SCIENCE

Targeted Ablation of Nesprin 1 and Nesprin 2 from Murine Myocardium Results in Cardiomyopathy, Altered Nuclear Morphology and Inhibition of the Biomechanical Gene Response

(2014) Indroneal Banerjee et al.   PLoS Genetics

Myosin II in mechanotransduction: master and commander of cell migration, morphogenesis, and cancer

(2013) Rocío Aguilar-Cuenca et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nuclear Mechanics and Mechanotransduction in Health and Disease

(2013) Philipp Isermann et al.   CURRENT BIOLOGY

Nesprins: from the nuclear envelope and beyond

(2013) Dipen Rajgor et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Technologies for deriving primary tumor cells for use in personalized cancer therapy

(2013) Abhisek Mitra et al.   TRENDS IN BIOTECHNOLOGY

Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancer

(2013) Sandro Goruppi et al.   TRENDS IN CELL BIOLOGY

The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction

(2013) Allison B. Chambliss et al.   Scientific Reports

Myosin IIA deficient cells migrate efficiently despite reduced traction forces at cell periphery

(2013) M. H. Jorrisch et al.   Biology Open

MYBPH inhibits NM IIA assembly via direct interaction with NMHC IIA and reduces cell motility

(2012) Yasuyuki Hosono et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The tumor suppressor Lgl1 regulates NMII-A cellular distribution and focal adhesion morphology to optimize cell migration

(2012) Inbal Dahan et al.   MOLECULAR BIOLOGY OF THE CELL

Actin cap associated focal adhesions and their distinct role in cellular mechanosensing

(2012) Dong-Hwee Kim et al.   Scientific Reports

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Increased expression of nonmuscle myosin IIs is associated with 3MC-induced mouse tumor

(2011) Shekhar Saha et al.   FEBS Journal

The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton

(2011) Maria L. Lombardi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association between  4 integrin cytoplasmic tail and non-muscle myosin IIA regulates cell migration

(2011) L. A. R. Rosado et al.   JOURNAL OF CELL SCIENCE

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

(2011) Amanda M Haidet-Phillips et al.   NATURE BIOTECHNOLOGY

RefilinB (FAM101B) targets FilaminA to organize perinuclear actin networks and regulates nuclear shape

(2011) O. Gay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myosin light chain mono- and di-phosphorylation differentially regulate adhesion and polarity in migrating cells

(2010) Miguel Vicente-Manzanares et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Linear Arrays of Nuclear Envelope Proteins Harness Retrograde Actin Flow for Nuclear Movement

(2010) G. W. G. Luxton et al.   SCIENCE

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A perinuclear actin cap regulates nuclear shape

(2009) Shyam B. Khatau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonmuscle myosin II moves in new directions

(2007) M. A. Conti et al.   JOURNAL OF CELL SCIENCE