Myosin II in mechanotransduction: master and commander of cell migration, morphogenesis, and cancer

Understanding the Cooperative Interaction between Myosin II and Actin Cross-Linkers Mediated by Actin Filaments during Mechanosensation

(2012) Tianzhi Luo et al.   BIOPHYSICAL JOURNAL

Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain

(2012) Matthew Raab et al.   JOURNAL OF CELL BIOLOGY

The nanomechanical signature of breast cancer

(2012) Marija Plodinec et al.   Nature Nanotechnology

The origins of the molecular era of adhesion research

(2012) Alan Rick Horwitz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell mechanics control rapid transitions between blebs and lamellipodia during migration

(2012) M. Bergert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Forces Driving Epithelial Spreading in Zebrafish Gastrulation

(2012) M. Behrndt et al.   SCIENCE

The epithelial–mesenchymal transition under control: Global programs to regulate epithelial plasticity

(2012) M. Angela Nieto et al.   SEMINARS IN CANCER BIOLOGY

Force Generation, Transmission, and Integration during Cell and Tissue Morphogenesis

(2011) Thomas Lecuit et al.   Annual Review of Cell and Developmental Biology

Actomyosin-Mediated Cellular Tension Drives Increased Tissue Stiffness and β-Catenin Activation to Induce Epidermal Hyperplasia and Tumor Growth

(2011) Michael S. Samuel et al.   CANCER CELL

Regulation of integrin affinity on cell surfaces

(2011) Thomas Schürpf et al.   EMBO JOURNAL

Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas

(2011) Gema Moreno-Bueno et al.   EMBO Molecular Medicine

The secret life of α-catenin: Moonlighting in morphogenesis

(2011) Stephanie L. Maiden et al.   JOURNAL OF CELL BIOLOGY

A tension-induced mechanotransduction pathway promotes epithelial morphogenesis

(2011) Huimin Zhang et al.   NATURE

Mechanical Integration of Actin and Adhesion Dynamics in Cell Migration

(2010) Margaret L. Gardel et al.   Annual Review of Cell and Developmental Biology

Dynamic interplay between the collagen scaffold and tumor evolution

(2010) Mikala Egeblad et al.   CURRENT OPINION IN CELL BIOLOGY

Apical constriction and invagination downstream of the canonical Wnt signaling pathway require Rho1 and Myosin II

(2010) Sandra G. Zimmerman et al.   DEVELOPMENTAL BIOLOGY

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

Anisotropies in cortical tension reveal the physical basis of polarizing cortical flows

(2010) Mirjam Mayer et al.   NATURE

Tissue elongation requires oscillating contractions of a basal actomyosin network

(2010) Li He et al.   NATURE CELL BIOLOGY

Biochemical and Structural Properties of the Integrin-Associated Cytoskeletal Protein Talin

(2009) David R. Critchley   Annual Review of Biophysics

Cell-Cycle Control by Physiological Matrix Elasticity and In Vivo Tissue Stiffening

(2009) Eric A. Klein et al.   CURRENT BIOLOGY

Mechanosensing through Cooperative Interactions between Myosin II and the Actin Crosslinker Cortexillin I

(2009) Yixin Ren et al.   CURRENT BIOLOGY

Myosin II Dynamics Are Regulated by Tension in Intercalating Cells

(2009) Rodrigo Fernandez-Gonzalez et al.   DEVELOPMENTAL CELL

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

Mechanically Activated Integrin Switch Controls  5 1 Function

(2009) J. C. Friedland et al.   SCIENCE

Cell Signaling in Space and Time: Where Proteins Come Together and When They're Apart

(2009) J. D. Scott et al.   SCIENCE

Mechanical Signals Trigger Myosin II Redistribution and Mesoderm Invagination in Drosophila Embryos

(2009) P.-A. Pouille et al.   Science Signaling

Regulation of the function of mammalian myosin and its conformational change

(2008) Mitsuo Ikebe   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

Interactions between Myosin and Actin Crosslinkers Control Cytokinesis Contractility Dynamics and Mechanics

(2008) Elizabeth M. Reichl et al.   CURRENT BIOLOGY

The α-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC

(2008) Kristopher Clark et al.   FEBS LETTERS

Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed

(2008) Margaret L. Gardel et al.   JOURNAL OF CELL BIOLOGY

TRPM7 Regulates Myosin IIA Filament Stability and Protein Localization by Heavy Chain Phosphorylation

(2008) Kristopher Clark et al.   JOURNAL OF MOLECULAR BIOLOGY

Rapid leukocyte migration by integrin-independent flowing and squeezing

(2008) Tim Lämmermann et al.   NATURE

Actin and α-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner

(2008) Colin K. Choi et al.   NATURE CELL BIOLOGY

Nature and anisotropy of cortical forces orienting Drosophila tissue morphogenesis

(2008) Matteo Rauzi et al.   NATURE CELL BIOLOGY

Epithelial morphogenesis in embryos: asymmetries, motors and brakes

(2008) Sophie Quintin et al.   TRENDS IN GENETICS

Nonmuscle myosin II moves in new directions

(2007) M. A. Conti et al.   JOURNAL OF CELL SCIENCE