Activation of ROCK and MLCK tunes regional stress fiber formation and mechanics via preferential myosin light chain phosphorylation

ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens

(2017) Rashmi Priya et al.   MOLECULAR BIOLOGY OF THE CELL

Actin dynamics and competition for myosin monomer govern the sequential amplification of myosin filaments

(2017) Jordan R. Beach et al.   NATURE CELL BIOLOGY

Geometry and network connectivity govern the mechanics of stress fibers

(2017) Elena Kassianidou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

N-terminal specific conjugation of extracellular matrix proteins to 2-pyridinecarboxaldehyde functionalized polyacrylamide hydrogels

(2016) Jessica P. Lee et al.   BIOMATERIALS

Synthetic mechanobiology: engineering cellular force generation and signaling

(2016) Jasmine Hannah Hughes et al.   CURRENT OPINION IN BIOTECHNOLOGY

Myosin di-phosphorylation and peripheral actin bundle formation as initial events during endothelial barrier disruption

(2016) Mayumi Hirano et al.   Scientific Reports

Drosophila non-muscle myosin II motor activity determines the rate of tissue folding

(2016) Claudia G Vasquez et al.   eLife

Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis

(2016) Sandra Kümper et al.   eLife

A biomechanical perspective on stress fiber structure and function

(2015) Elena Kassianidou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Constitutive Activation of Myosin-Dependent Contractility Sensitizes Glioma Tumor-Initiating Cells to Mechanical Inputs and Reduces Tissue Invasion

(2015) S. Y. Wong et al.   CANCER RESEARCH

ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity

(2015) Karen A. Newell-Litwa et al.   JOURNAL OF CELL BIOLOGY

A synthetic hydrogel for the high-throughput study of cell–ECM interactions

(2015) Andrew D. Rape et al.   Nature Communications

Differential Contributions of Nonmuscle Myosin II Isoforms and Functional Domains to Stress Fiber Mechanics

(2015) Ching-Wei Chang et al.   Scientific Reports

Model-based Traction Force Microscopy Reveals Differential Tension in Cellular Actin Bundles

(2015) Jérôme R. D. Soiné et al.   PLoS Computational Biology

Nonmuscle Myosin II Isoforms Coassemble in Living Cells

(2014) Jordan R. Beach et al.   CURRENT BIOLOGY

Karyotypically distinct U251, U373, and SNB19 glioma cell lines are of the same origin but have different drug treatment sensitivities

(2014) Alexey A. Stepanenko et al.   GENE

Simultaneous and independent tuning of RhoA and Rac1 activity with orthogonally inducible promoters

(2014) Joanna L. MacKay et al.   Integrative Biology

A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells

(2014) Dylan T. Burnette et al.   JOURNAL OF CELL BIOLOGY

A mechanical-biochemical feedback loop regulates remodeling in the actin cytoskeleton

(2014) Matthew R. Stachowiak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Forces in Tissue Morphogenesis and Patterning

(2013) Carl-Philipp Heisenberg et al.   CELL

Vinculin tension distributions of individual stress fibers within cell-matrix adhesions

(2013) C.-W. Chang et al.   JOURNAL OF CELL SCIENCE

Opposing Signaling of ROCK1 and ROCK2 Determines the Switching of Substrate Specificity and the Mode of Migration of Glioblastoma Cells

(2013) Sonja Mertsch et al.   MOLECULAR NEUROBIOLOGY

Biophysical regulation of epigenetic state and cell reprogramming

(2013) Timothy L. Downing et al.   NATURE MATERIALS

Three-dimensional patterning of multiple cell populations through orthogonal genetic control of cell motility

(2013) Joanna L. MacKay et al.   Soft Matter

A Genetic Strategy for the Dynamic and Graded Control of Cell Mechanics, Motility, and Matrix Remodeling

(2012) Joanna L. MacKay et al.   BIOPHYSICAL JOURNAL

Dynamic Regulation of Myosin Light Chain Phosphorylation by Rho-kinase

(2012) Takako Kaneko-Kawano et al.   PLoS One

Spatial organization of the extracellular matrix regulates cell-cell junction positioning

(2012) Q. Tseng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibroblast polarization is a matrix-rigidity-dependent process controlled by focal adhesion mechanosensing

(2011) Masha Prager-Khoutorsky et al.   NATURE CELL BIOLOGY

Collective cell guidance by cooperative intercellular forces

(2011) Dhananjay T. Tambe et al.   NATURE MATERIALS

Myosin light chain mono- and di-phosphorylation differentially regulate adhesion and polarity in migrating cells

(2010) Miguel Vicente-Manzanares et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dissecting Regional Variations in Stress Fiber Mechanics in Living Cells with Laser Nanosurgery

(2010) Kandice Tanner et al.   BIOPHYSICAL JOURNAL

Differential phosphorylation of myosin light chain (Thr)18 and (Ser)19 and functional implications in platelets

(2010) T. M. GETZ et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Sarcomere Mechanics in Capillary Endothelial Cells

(2009) Robert J. Russell et al.   BIOPHYSICAL JOURNAL

ROCK Isoform Regulation of Myosin Phosphatase and Contractility in Vascular Smooth Muscle Cells

(2009) Yuepeng Wang et al.   CIRCULATION RESEARCH

Mechanosensing in actin stress fibers revealed by a close correlation between force and protein localization

(2009) J. Colombelli et al.   JOURNAL OF CELL SCIENCE

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Kinetics of stress fibers

(2008) Matthew R Stachowiak et al.   NEW JOURNAL OF PHYSICS