Elevated exosomal lysyl oxidase like 2 is a potential biomarker for head and neck squamous cell carcinoma

Exosome-Mediated Regulation of Tumor Immunology

(2018) Naohiro Seo et al.   CANCER SCIENCE

Exosomes in cancer development and clinical applications

(2018) Yu-Ling Tai et al.   CANCER SCIENCE

Squamous Cell Carcinoma Antigen 2 (SCCA2, SERPINB4): An Emerging Biomarker for Skin Inflammatory Diseases

(2018) Kenji Izuhara et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Secretory microRNAs as biomarkers of cancer

(2018) Kazuharu Kai et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Exosome-related tumor microenvironment

(2018) Cheng Hu et al.   Journal of Cancer

Proteolytic processing of lysyl oxidase–like-2 in the extracellular matrix is required for crosslinking of basement membrane collagen IV

(2017) Alberto J. López-Jiménez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Liquid biopsy: An emerging prognostic and predictive tool in Head and Neck Squamous Cell Carcinoma (HNSCC). Focus on Circulating Tumor Cells (CTCs)

(2017) P. Economopoulou et al.   ORAL ONCOLOGY

Risk Factors for Distant Metastasis in Patients with Oral Cavity Squamous Cell Carcinoma Undergoing Surgical Treatment

(2017) Felipe Toyama Aires et al.   ORL-Journal for Oto-Rhino-Laryngology Head and Neck Surgery

Prions on the run: How extracellular vesicles serve as delivery vehicles for self-templating protein aggregates

(2017) Shu Liu et al.   Prion

Lymph node ratio relationship to regional failure and distant metastases in oral cavity cancer

(2017) Ali Hosni et al.   RADIOTHERAPY AND ONCOLOGY

A combination of circulating miRNAs for the early detection of ovarian cancer

(2017) Akira Yokoi et al.   Oncotarget

Comprehensive microRNA-sequencing of exosomes derived from head and neck carcinoma cells in vitro reveals common secretion profiles and potential utility as salivary biomarkers

(2017) Scott Langevin et al.   Oncotarget

Exosomes and the Prion Protein: More than One Truth

(2017) Alexander Hartmann et al.   Frontiers in Neuroscience

Functional importance of lysyl oxidase family propeptide regions

(2017) Philip C. Trackman   Journal of Cell Communication and Signaling

The value of squamous cell carcinoma antigen (SCCa) to determine the lymph nodal metastasis in cervical cancer: A meta-analysis and literature review

(2017) Ziqi Zhou et al.   PLoS One

LOXL2 drives epithelial-mesenchymal transition via activation of IRE1-XBP1 signalling pathway

(2017) Eva P. Cuevas et al.   Scientific Reports

Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis

(2016) Thomas R. Cox et al.   CANCER RESEARCH

Lysyl oxidase-like 2 (LOXL2) oxidizes trimethylated lysine 4 in histone H3

(2016) Nicolás Herranz et al.   FEBS Journal

A truncated splice variant of human lysyl oxidase-like 2 promotes migration and invasion in esophageal squamous cell carcinoma

(2016) Hai-Ying Zou et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

LOXL2 Is Highly Expressed in Cancer-Associated Fibroblasts and Associates to Poor Colon Cancer Survival

(2015) S. Torres et al.   CLINICAL CANCER RESEARCH

Exosomes from hypoxic endothelial cells have increased collagen crosslinking activity through up-regulation of lysyl oxidase-like 2

(2015) Olivier G. de Jong et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

LOXL2 Oxidizes Methylated TAF10 and Controls TFIID-Dependent Genes during Neural Progenitor Differentiation

(2015) Ane Iturbide et al.   MOLECULAR CELL

Exosomes mediate the acquisition of the disease phenotypes by cells with normal genome in tuberous sclerosis complex

(2015) B Patel et al.   ONCOGENE

Identification of a novel lysyl oxidase-like 2 alternative splicing isoform, LOXL2 Δe13, in esophageal squamous cell carcinoma

(2014) Guo-Qing Lv et al.   Biochemistry and Cell Biology

Human lysyl oxidase-like 2

(2014) Hee-Jung Moon et al.   BIOORGANIC CHEMISTRY

A new role for LOX and LOXL2 proteins in transcription regulation

(2014) Ane Iturbide et al.   FEBS Journal

Lysyl oxidase-like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma

(2014) Carmen Chak-Lui Wong et al.   HEPATOLOGY

Decreased Amyloid-β Pathologies by Intracerebral Loading of Glycosphingolipid-enriched Exosomes in Alzheimer Model Mice

(2014) Kohei Yuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysyl oxidase-like 2 (LOXL2) and E47 EMT factor: novel partners in E-cadherin repression and early metastasis colonization

(2014) G Canesin et al.   ONCOGENE

Pathological roles of ceramide and its metabolites in metabolic syndrome and Alzheimer's disease

(2013) Kohei Yuyama et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

LOXL2 expression is associated with invasiveness and negatively influences survival in breast cancer patients

(2013) Sung Gwe Ahn et al.   BREAST CANCER RESEARCH AND TREATMENT

Regulation of Heterochromatin Transcription by Snail1/LOXL2 during Epithelial-to-Mesenchymal Transition

(2013) Alba Millanes-Romero et al.   MOLECULAR CELL

Sphingolipid-modulated Exosome Secretion Promotes Clearance of Amyloid-β by Microglia

(2012) Kohei Yuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Premetastatic vasculogenesis in oral squamous cell carcinoma xenograft-draining lymph nodes

(2012) Alejandro E. Mayorca-Guiliani et al.   ORAL ONCOLOGY

The Tumor Suppressor PTEN Is Exported in Exosomes and Has Phosphatase Activity in Recipient Cells

(2012) U. Putz et al.   Science Signaling

Reduced nuclear and ectopic cytoplasmic expression of lysyl oxidase–like 2 is associated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma

(2011) Tian-Yu Li et al.   HUMAN PATHOLOGY

Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche

(2009) Janine T. Erler et al.   CANCER CELL

Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway

(2009) Liang Peng et al.   CARCINOGENESIS

The Lysyl Oxidases LOX and LOXL2 Are Necessary and Sufficient to Repress E-cadherin in Hypoxia

(2009) Ruth Schietke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysyl Oxidase-Like 2 as a New Poor Prognosis Marker of Squamous Cell Carcinomas

(2008) H. Peinado et al.   CANCER RESEARCH