LOXL2 drives epithelial-mesenchymal transition via activation of IRE1-XBP1 signalling pathway

Protein misfolding in the endoplasmic reticulum as a conduit to human disease

(2016) Miao Wang et al.   NATURE

NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK–eIF2α–ATF4 signalling in breast cancer

(2016) A Gupta et al.   ONCOGENE

XBP1 induces snail expression to promote epithelial- to-mesenchymal transition and invasion of breast cancer cells

(2015) Haiyu Li et al.   CELLULAR SIGNALLING

Divergent androgen regulation of unfolded protein response pathways drives prostate cancer

(2015) X. Sheng et al.   EMBO Molecular Medicine

Exosomes from hypoxic endothelial cells have increased collagen crosslinking activity through up-regulation of lysyl oxidase-like 2

(2015) Olivier G. de Jong et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

Origin and evolution of lysyl oxidases

(2015) Xavier Grau-Bové et al.   Scientific Reports

Human copper-dependent amine oxidases

(2014) Joel Finney et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

(2014) Xi Chen et al.   NATURE

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lysyl oxidase-like 2 (LOXL2) and E47 EMT factor: novel partners in E-cadherin repression and early metastasis colonization

(2014) G Canesin et al.   ONCOGENE

Proteomic analysis of hypoxia-induced U373MG glioma secretome reveals novel hypoxia-dependent migration factors

(2014) Jong Hyuk Yoon et al.   PROTEOMICS

Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters

(2014) Alexandra Naba et al.   eLife

LOXL2 catalytically inactive mutants mediate epithelial-to-mesenchymal transition

(2014) E. P. Cuevas et al.   Biology Open

Post-translational Modifications of Recombinant Human Lysyl Oxidase-like 2 (rhLOXL2) Secreted fromDrosophilaS2 Cells

(2013) Li Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MCF-7 Cells Expressing Nuclear Associated Lysyl Oxidase-like 2 (LOXL2) Exhibit an Epithelial-to-Mesenchymal Transition (EMT) Phenotype and Are Highly Invasivein Vitro

(2013) Hee-Jung Moon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective inhibition of the unfolded protein response: targeting catalytic sites for Schiff base modification

(2013) Susana M. Tomasio et al.   Molecular BioSystems

Regulation of Heterochromatin Transcription by Snail1/LOXL2 during Epithelial-to-Mesenchymal Transition

(2013) Alba Millanes-Romero et al.   MOLECULAR CELL

Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells

(2013) M. A. Nieto   SCIENCE

Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments

(2013) Matthew D. Shoulders et al.   Cell Reports

ERLIN2 promotes breast cancer cell survival by modulating endoplasmic reticulum stress pathways

(2012) Guohui Wang et al.   BMC CANCER

Lysyl Oxidase: From Basic Science to Future Cancer Treatment

(2012) Takeshi Nishioka et al.   CELL STRUCTURE AND FUNCTION

LOXL2 in epithelial cell plasticity and tumor progression

(2012) Amparo Cano et al.   Future Oncology

The epithelial–mesenchymal transition under control: Global programs to regulate epithelial plasticity

(2012) M. Angela Nieto et al.   SEMINARS IN CANCER BIOLOGY

The Ins and Outs of the Epithelial to Mesenchymal Transition in Health and Disease

(2011) M. Angela Nieto   Annual Review of Cell and Developmental Biology

Role of Endoplasmic Reticulum Stress in Metabolic Disease and Other Disorders

(2011) Lale Ozcan et al.   Annual Review of Medicine

Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane

(2011) M. Bignon et al.   BLOOD

LOXL2-Mediated Matrix Remodeling in Metastasis and Mammary Gland Involution

(2011) H. E. Barker et al.   CANCER RESEARCH

Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas

(2011) Gema Moreno-Bueno et al.   EMBO Molecular Medicine

The Role of Lysyl Oxidase in SRC-Dependent Proliferation and Metastasis of Colorectal Cancer

(2011) Ann-Marie Baker et al.   JNCI-Journal of the National Cancer Institute

The Conserved Scavenger Receptor Cysteine-Rich Superfamily in Therapy and Diagnosis

(2011) V. G. Martinez et al.   PHARMACOLOGICAL REVIEWS

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

The Lysyl Oxidases LOX and LOXL2 Are Necessary and Sufficient to Repress E-cadherin in Hypoxia

(2009) Ruth Schietke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

The morphological and molecular features of the epithelial-to-mesenchymal transition

(2009) Gema Moreno-Bueno et al.   Nature Protocols

Lysyl Oxidase-Like 2 as a New Poor Prognosis Marker of Squamous Cell Carcinomas

(2008) H. Peinado et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Transcriptional regulation of cell polarity in EMT and cancer

(2008) G Moreno-Bueno et al.   ONCOGENE