Extracellular matrix dynamics in cell migration, invasion and tissue morphogenesis

Durotaxis by Human Cancer Cells

(2019) Brian J. DuChez et al.   BIOPHYSICAL JOURNAL

Organoids — Preclinical Models of Human Disease

(2019) Mo Li et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adaptive F-Actin Polymerization and Localized ATP Production Drive Basement Membrane Invasion in the Absence of MMPs

(2019) Laura C. Kelley et al.   DEVELOPMENTAL CELL

Mechanosensing at integrin-mediated cell–matrix adhesions: from molecular to integrated mechanisms

(2018) Nils C Gauthier et al.   CURRENT OPINION IN CELL BIOLOGY

Use and application of 3D-organoid technology

(2018) Benedetta Artegiani et al.   HUMAN MOLECULAR GENETICS

Live Imaging of Type I Collagen Assembly Dynamics in Osteoblasts Stably Expressing GFP and mCherry-Tagged Collagen Constructs

(2018) Yongbo Lu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Therapeutic approaches to control tissue repair and fibrosis: Extracellular matrix as a game changer

(2018) Mariëlle Walraven et al.   MATRIX BIOLOGY

Loss of KLHL6 promotes diffuse large B-cell lymphoma growth and survival by stabilizing the mRNA decay factor roquin2

(2018) Jaewoo Choi et al.   NATURE CELL BIOLOGY

3D culture models for studying branching morphogenesis in the mammary gland and mammalian lung

(2018) Bryan A. Nerger et al.   BIOMATERIALS

Modeling Host-Pathogen Interactions in the Context of the Microenvironment: 3-D Cell Culture Comes of Age

(2018) Jennifer Barrila et al.   INFECTION AND IMMUNITY

A fluid-to-solid jamming transition underlies vertebrate body axis elongation

(2018) Alessandro Mongera et al.   NATURE

Progress and potential in organoid research

(2018) Giuliana Rossi et al.   NATURE REVIEWS GENETICS

Building Models of Brain Disorders with Three-Dimensional Organoids

(2018) Neal D. Amin et al.   NEURON

Forces drive basement membrane invasion inCaenorhabditis elegans

(2018) Rodrigo Cáceres et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of orthotopically functional salivary gland from embryonic stem cells

(2018) Junichi Tanaka et al.   Nature Communications

Bioengineering-inspired three-dimensional culture systems: Organoids to create tumor microenvironment

(2018) Pelin Saglam-Metiner et al.   GENE

Signal transduction via integrin adhesion complexes

(2018) Jonathan D Humphries et al.   CURRENT OPINION IN CELL BIOLOGY

The Mechanics of Single Cell and Collective Migration of Tumor Cells

(2017) Marianne Lintz et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Patterned cell and matrix dynamics in branching morphogenesis

(2017) Shaohe Wang et al.   JOURNAL OF CELL BIOLOGY

Goodbye flat biology – time for the 3rd and the 4th dimensions

(2017) Mina J. Bissell   JOURNAL OF CELL SCIENCE

Force-dependent breaching of the basement membrane

(2017) Tammy T. Chang et al.   MATRIX BIOLOGY

The nature and biology of basement membranes

(2017) Ambra Pozzi et al.   MATRIX BIOLOGY

Matrix biomechanics and dynamics in pulmonary fibrosis

(2017) Andrew J. Haak et al.   MATRIX BIOLOGY

Mechanoreciprocity in cell migration

(2017) Sjoerd van Helvert et al.   NATURE CELL BIOLOGY

Modeling Physiological Events in 2D vs. 3D Cell Culture

(2017) Kayla Duval et al.   PHYSIOLOGY

Building collagen IV smart scaffolds on the outside of cells

(2017) Kyle L. Brown et al.   PROTEIN SCIENCE

Actin-Based Adhesion Modules Mediate Cell Interactions with the Extracellular Matrix and Neighboring Cells

(2017) Alexia I. Bachir et al.   Cold Spring Harbor Perspectives in Biology

Three-dimensional collagen matrix induces a mechanosensitive invasive epithelial phenotype

(2017) Shawn P. Carey et al.   Scientific Reports

Focal Adhesion–Independent Cell Migration

(2016) Ewa K. Paluch et al.   Annual Review of Cell and Developmental Biology

Plasticity of Cell Migration In Vivo and In Silico

(2016) Veronika te Boekhorst et al.   Annual Review of Cell and Developmental Biology

Extracellular matrix motion and early morphogenesis

(2016) Rajprasad Loganathan et al.   DEVELOPMENT

Activating the nuclear piston mechanism of 3D migration in tumor cells

(2016) Ryan J. Petrie et al.   JOURNAL OF CELL BIOLOGY

3D culture models of tissues under tension

(2016) Jeroen Eyckmans et al.   JOURNAL OF CELL SCIENCE

Collective cell durotaxis emerges from long-range intercellular force transmission

(2016) R. Sunyer et al.   SCIENCE

Collagen Matrix Density Drives the Metabolic Shift in Breast Cancer Cells

(2016) Brett A. Morris et al.   EBioMedicine

Cortical Contractility Triggers a Stochastic Switch to Fast Amoeboid Cell Motility

(2015) Verena Ruprecht et al.   CELL

Structural basis of Keap1 interactions with Nrf2

(2015) Peter Canning et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protrusive waves guide 3D cell migration along nanofibers

(2015) Charlotte Guetta-Terrier et al.   JOURNAL OF CELL BIOLOGY

Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network

(2015) Vira V. Artym et al.   JOURNAL OF CELL BIOLOGY

Cell-fate determination by ubiquitin-dependent regulation of translation

(2015) Achim Werner et al.   NATURE

Local 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions

(2015) Andrew D. Doyle et al.   Nature Communications

Cellular and physical mechanisms of branching morphogenesis

(2014) Victor D. Varner et al.   DEVELOPMENT

Local and global dynamics of the basement membrane during branching morphogenesis require protease activity and actomyosin contractility

(2014) Jill S. Harunaga et al.   DEVELOPMENTAL BIOLOGY

Physical influences of the extracellular environment on cell migration

(2014) Guillaume Charras et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Generation of compartmentalized pressure by a nuclear piston governs cell motility in a 3D matrix

(2014) R. J. Petrie et al.   SCIENCE

Stiff Collagen Matrices Increase Tumorigenic Prolactin Signaling in Breast Cancer Cells

(2013) Craig E. Barcus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nonpolarized signaling reveals two distinct modes of 3D cell migration

(2012) Ryan J. Petrie et al.   JOURNAL OF CELL BIOLOGY

Branching Morphogenesis: From Cells to Organs and Back

(2012) A. Ochoa-Espinosa et al.   Cold Spring Harbor Perspectives in Biology

Extracellular matrix receptors in branched organs

(2011) Ambra Pozzi et al.   CURRENT OPINION IN CELL BIOLOGY

Fibronectins, Their Fibrillogenesis, and In Vivo Functions

(2011) J. E. Schwarzbauer et al.   Cold Spring Harbor Perspectives in Biology

Dynamic membrane remodeling at invadopodia differentiates invadopodia from podosomes

(2010) Vira V. Artym et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Btbd7 Regulates Epithelial Cell Dynamics and Branching Morphogenesis

(2010) T. Onodera et al.   SCIENCE

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution

(2009) Gianni Carraro et al.   DEVELOPMENTAL BIOLOGY

One-dimensional topography underlies three-dimensional fibrillar cell migration

(2009) Andrew D. Doyle et al.   JOURNAL OF CELL BIOLOGY

Collagen density promotes mammary tumor initiation and progression

(2008) Paolo P Provenzano et al.   BMC Medicine

Collective Epithelial Migration and Cell Rearrangements Drive Mammary Branching Morphogenesis

(2008) Andrew J. Ewald et al.   DEVELOPMENTAL CELL

MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators

(2008) G. Gabriely et al.   MOLECULAR AND CELLULAR BIOLOGY