Methodological challenges in constructing DNA methylation risk scores
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Methodological challenges in constructing DNA methylation risk scores
Authors
Keywords
-
Journal
Epigenetics
Volume -, Issue -, Pages 1-11
Publisher
Informa UK Limited
Online
2019-07-18
DOI
10.1080/15592294.2019.1644879
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Variance component tests of multivariate mediation effects under composite null hypotheses
- (2019) Yen‐Tsung Huang BIOMETRICS
- Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood
- (2019) Amit V. Khera et al. CELL
- Global test for high‐dimensional mediation: Testing groups of potential mediators
- (2019) Vera Djordjilović et al. STATISTICS IN MEDICINE
- FUN-LDA: A Latent Dirichlet Allocation Model for Predicting Tissue-Specific Functional Effects of Noncoding Variation: Methods and Applications
- (2018) Daniel Backenroth et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Impact on birth weight of maternal smoking throughout pregnancy mediated by DNA methylation
- (2018) Stephanie H. Witt et al. BMC GENOMICS
- Atopic dermatitis: Interaction between genetic variants of GSTP1 ,TNF ,TLR2 , and TLR4 and air pollution in early life
- (2018) Anke Hüls et al. PEDIATRIC ALLERGY AND IMMUNOLOGY
- DNA methylation as a predictor of fetal alcohol spectrum disorder
- (2018) Alexandre A. Lussier et al. Clinical Epigenetics
- DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons
- (2018) Olivera Story Jovanova et al. JAMA Psychiatry
- DNA methylation in childhood asthma: an epigenome-wide meta-analysis
- (2018) Cheng-Jian Xu et al. Lancet Respiratory Medicine
- DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood
- (2018) Elmar W. Tobi et al. Science Advances
- Predicting polygenic risk of psychiatric disorders
- (2018) Alicia R. Martin et al. BIOLOGICAL PSYCHIATRY
- Genetic susceptibility for air pollution-induced airway inflammation in the SALIA study
- (2017) Anke Hüls et al. ENVIRONMENTAL RESEARCH
- Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium
- (2017) Gemma C Sharp et al. HUMAN MOLECULAR GENETICS
- Functional mapping and annotation of genetic associations with FUMA
- (2017) Kyoko Watanabe et al. Nature Communications
- Gene-environment interaction study for BMI reveals interactions between genetic factors and physical activity, alcohol consumption and socioeconomic status
- (2017) Mathias Rask-Andersen et al. PLoS Genetics
- DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
- (2016) Bonnie R. Joubert et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Estimating and testing high-dimensional mediation effects in epigenetic studies
- (2016) Haixiang Zhang et al. BIOINFORMATICS
- Associations of genetic risk scores based on adult adiposity pathways with childhood growth and adiposity measures
- (2016) Claire Monnereau et al. BMC GENETICS
- Air pollution and diabetes association: Modification by type 2 diabetes genetic risk score
- (2016) Ikenna C. Eze et al. ENVIRONMENT INTERNATIONAL
- Polygenic Epidemiology
- (2016) Frank Dudbridge GENETIC EPIDEMIOLOGY
- Challenges and novel approaches for investigating molecular mediation
- (2016) R.C. Richmond et al. HUMAN MOLECULAR GENETICS
- Epigenome-wide association study of body mass index and the adverse outcomes of adiposity
- (2016) Simone Wahl et al. NATURE
- Risk score predicts high-grade prostate cancer in DNA-methylation positive, histopathologically negative biopsies
- (2016) Leander Van Neste et al. PROSTATE
- Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data
- (2016) Jianxin Shi et al. PLoS Genetics
- Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations
- (2015) Sonia Shah et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores
- (2015) Bjarni J. Vilhjálmsson et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A proposed clinical and biological interpretation of mediated interaction
- (2015) M. Arfan Ikram et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Contemporary Considerations for Constructing a Genetic Risk Score: An Empirical Approach
- (2015) Benjamin A. Goldstein et al. GENETIC EPIDEMIOLOGY
- DNA methylation-based prognosis and epidrivers in hepatocellular carcinoma
- (2015) Augusto Villanueva et al. HEPATOLOGY
- DNA methylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring
- (2015) Leanne K Küpers et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936
- (2015) Riccardo E Marioni et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- HIV-1 Infection Accelerates Age According to the Epigenetic Clock
- (2015) Steve Horvath et al. JOURNAL OF INFECTIOUS DISEASES
- Partitioning heritability by functional annotation using genome-wide association summary statistics
- (2015) Hilary K Finucane et al. NATURE GENETICS
- Combining information on multiple instrumental variables in Mendelian randomization: comparison of allele score and summarized data methods
- (2015) Stephen Burgess et al. STATISTICS IN MEDICINE
- mediation:RPackage for Causal Mediation Analysis
- (2015) Dustin Tingley et al. Journal of Statistical Software
- PRSice: Polygenic Risk Score software
- (2014) Jack Euesden et al. BIOINFORMATICS
- Research Review: Polygenic methods and their application to psychiatric traits
- (2014) Naomi R. Wray et al. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
- Fried food consumption, genetic risk, and body mass index: gene-diet interaction analysis in three US cohort studies
- (2014) Q. Qi et al. BMJ-British Medical Journal
- Differences in smoking associated DNA methylation patterns in South Asians and Europeans
- (2014) Hannah R Elliott et al. Clinical Epigenetics
- The Power of Meta-Analysis in Genome-Wide Association Studies
- (2013) Orestis A. Panagiotou et al. Annual Review of Genomics and Human Genetics
- DNA methylation score is predictive of myeloma cell sensitivity to 5-azacitidine
- (2013) Jerome Moreaux et al. BRITISH JOURNAL OF HAEMATOLOGY
- Strategies for Developing Prediction Models From Genome-Wide Association Studies
- (2013) Jincao Wu et al. GENETIC EPIDEMIOLOGY
- DNA methylation contributes to natural human variation
- (2013) H. Heyn et al. GENOME RESEARCH
- Use of allele scores as instrumental variables for Mendelian randomization
- (2013) Stephen Burgess et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Gene × Physical Activity Interactions in Obesity: Combined Analysis of 111,421 Individuals of European Ancestry
- (2013) Shafqat Ahmad et al. PLoS Genetics
- Power and Predictive Accuracy of Polygenic Risk Scores
- (2013) Frank Dudbridge PLoS Genetics
- Evaluation of genetic risk score models in the presence of interaction and linkage disequilibrium
- (2013) Ronglin Che et al. Frontiers in Genetics
- Polygenic dissection of the bipolar phenotype
- (2011) M. L. Hamshere et al. BRITISH JOURNAL OF PSYCHIATRY
- Physical Activity Attenuates the Genetic Predisposition to Obesity in 20,000 Men and Women from EPIC-Norfolk Prospective Population Study
- (2010) Shengxu Li et al. PLOS MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation