The Power of Meta-Analysis in Genome-Wide Association Studies

Methods for Meta-Analyses of Genome-wide Association Studies: Critical Assessment of Empirical Evidence

(2012) Martin Gögele et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Five Years of GWAS Discovery

(2012) Peter M. Visscher et al.   AMERICAN JOURNAL OF HUMAN GENETICS

zCall: a rare variant caller for array-based genotyping

(2012) Jacqueline I. Goldstein et al.   BIOINFORMATICS

Optimal tests for rare variant effects in sequencing association studies

(2012) S. Lee et al.   BIOSTATISTICS

A Combined Functional Annotation Score for Non-Synonymous Variants

(2012) Margarida C. Lopes et al.   HUMAN HEREDITY

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

(2012) Eli A Stahl et al.   NATURE GENETICS

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

The mystery of missing heritability: Genetic interactions create phantom heritability

(2012) O. Zuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

(2012) M. T. Maurano et al.   SCIENCE

Improving the Assessment of the Outcome of Nonsynonymous SNVs with a Consensus Deleteriousness Score, Condel

(2011) Abel González-Pérez et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Random-Effects Model Aimed at Discovering Associations in Meta-Analysis of Genome-wide Association Studies

(2011) Buhm Han et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The False-positive to False-negative Ratio in Epidemiologic Studies

(2011) John P. A. Ioannidis et al.   EPIDEMIOLOGY

Consistency of genome-wide associations across major ancestral groups

(2011) Evangelia E. Ntzani et al.   HUMAN GENETICS

Genome-wide association study of body height in African Americans: the Women's Health Initiative SNP Health Association Resource (SHARe)

(2011) Cara L. Carty et al.   HUMAN MOLECULAR GENETICS

What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations

(2011) Orestis A Panagiotou et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Comparison of Effect Sizes Associated With Biomarkers Reported in Highly Cited Individual Articles and in Subsequent Meta-analyses

(2011) John P. A. Ioannidis   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Large-scale genome-wide association studies in east Asians identify new genetic loci influencing metabolic traits

(2011) Young Jin Kim et al.   NATURE GENETICS

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

(2011) Norihiro Kato et al.   NATURE GENETICS

Schizophrenia Genetics: Where Next?

(2011) Y. Kim et al.   SCHIZOPHRENIA BULLETIN

Synthetic Associations Are Unlikely to Account for Many Common Disease Genome-Wide Association Signals

(2011) Carl A. Anderson et al.   PLOS BIOLOGY

Identification, Replication, and Fine-Mapping of Loci Associated with Adult Height in Individuals of African Ancestry

(2011) Amidou N'Diaye et al.   PLoS Genetics

Fine Mapping of Five Loci Associated with Low-Density Lipoprotein Cholesterol Detects Variants That Double the Explained Heritability

(2011) Serena Sanna et al.   PLoS Genetics

Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project

(2011) Guillaume Lettre et al.   PLoS Genetics

Genome-wide Significant Associations for Variants With Minor Allele Frequency of 5% or Less—An Overview: A HuGE Review

(2010) Orestis A. Panagiotou et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Prioritizing GWAS Results: A Review of Statistical Methods and Recommendations for Their Application

(2010) Rita M. Cantor et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Rare Variant Association Analysis Methods for Complex Traits

(2010) Jennifer Asimit et al.   Annual Review of Genetics

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

On the relative efficiency of using summary statistics versus individual-level data in meta-analysis

(2010) D. Y. Lin et al.   BIOMETRIKA

Imputation aware meta-analysis of genome-wide association studies

(2010) Noah Zaitlen et al.   GENETIC EPIDEMIOLOGY

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

(2010) Kiran Musunuru et al.   NATURE

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Estimation of effect size distribution from genome-wide association studies and implications for future discoveries

(2010) Ju-Hyun Park et al.   NATURE GENETICS

Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation

(2010) Geneviève Galarneau et al.   NATURE GENETICS

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Laboratory Mouse Models for the Human Genome-Wide Associations

(2010) Georgios D. Kitsios et al.   PLoS One

Replication in Genome-Wide Association Studies

(2010) Peter Kraft et al.   STATISTICAL SCIENCE

Rare Variants Create Synthetic Genome-Wide Associations

(2010) Samuel P. Dickson et al.   PLOS BIOLOGY

Discovery Properties of Genome-wide Association Signals From Cumulatively Combined Data Sets

(2009) T. V. Pereira et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Genotyping Technologies for Genetic Research

(2009) Jiannis Ragoussis   Annual Review of Genomics and Human Genetics

Genotype Imputation

(2009) Yun Li et al.   Annual Review of Genomics and Human Genetics

Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs

(2009) Anke Tönjes et al.   HUMAN MOLECULAR GENETICS

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits

(2009) Yoon Shin Cho et al.   NATURE GENETICS

Genome-wide association study identifies eight loci associated with blood pressure

(2009) Christopher Newton-Cheh et al.   NATURE GENETICS

Genome-wide association study of blood pressure and hypertension

(2009) Daniel Levy et al.   NATURE GENETICS

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Validating, augmenting and refining genome-wide association signals

(2009) John P. A. Ioannidis et al.   NATURE REVIEWS GENETICS

Genomewide Association Studies — Illuminating Biologic Pathways

(2009) Joel N. Hirschhorn   NEW ENGLAND JOURNAL OF MEDICINE

Common Genetic Variation and Human Traits

(2009) David B. Goldstein   NEW ENGLAND JOURNAL OF MEDICINE

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes

(2009) S. Nejentsev et al.   SCIENCE

Meta-Analysis of Genome-Wide Scans for Human Adult Stature Identifies Novel Loci and Associations with Measures of Skeletal Frame Size

(2009) Nicole Soranzo et al.   PLoS Genetics

Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions

(2009) Soumya Raychaudhuri et al.   PLoS Genetics

Forty-Three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-Wide Analysis

(2009) Daniel I. Chasman et al.   PLoS Genetics

Methods for Detecting Associations with Rare Variants for Common Diseases: Application to Analysis of Sequence Data

(2008) Bingshan Li et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Estimation of the multiple testing burden for genomewide association studies of nearly all common variants

(2008) Itsik Pe'er et al.   GENETIC EPIDEMIOLOGY

Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis

(2008) Åsa Johansson et al.   HUMAN MOLECULAR GENETICS

Practical aspects of imputation-driven meta-analysis of genome-wide association studies

(2008) P. I.W. de Bakker et al.   HUMAN MOLECULAR GENETICS

A HapMap harvest of insights into the genetics of common disease

(2008) Teri A. Manolio et al.   JOURNAL OF CLINICAL INVESTIGATION

Common variants in the GDF5-UQCC region are associated with variation in human height

(2008) Serena Sanna et al.   NATURE GENETICS

Common variants at 30 loci contribute to polygenic dyslipidemia

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Genome-wide association analysis identifies 20 loci that influence adult height

(2008) Michael N Weedon et al.   NATURE GENETICS

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

(2008) Cristen J Willer et al.   NATURE GENETICS

Many sequence variants affecting diversity of adult human height

(2008) Daniel F Gudbjartsson et al.   NATURE GENETICS

Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides

(2008) Jaspal S Kooner et al.   NATURE GENETICS

Identification of ten loci associated with height highlights new biological pathways in human growth

(2008) Guillaume Lettre et al.   NATURE GENETICS

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

(2008) Cristen J Willer et al.   NATURE GENETICS

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

(2008) Yurii S Aulchenko et al.   NATURE GENETICS

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

(2008) Mark I. McCarthy et al.   NATURE REVIEWS GENETICS

Genetic Mapping in Human Disease

(2008) D. Altshuler et al.   SCIENCE