Glycopeptides by Linch‐Pin C−H Activations for Peptide‐Carbohydrate Conjugation by Manganese(I)‐Catalysis

Divergent Synthesis of Silicon-Containing Peptides via Pd-Catalyzed Post-Assembly γ-C(sp3)–H Silylation

(2019) Bei-Bei Zhan et al.   ACS Catalysis

Electrochemically Driven, Ni-Catalyzed Aryl Amination: Scope, Mechanism, and Applications

(2019) Yu Kawamata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Late-Stage Functionalization of Peptides and Cyclopeptides Using Organozinc Reagents

(2019) Marcel Leroux et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Peptide Modifications: Versatile Tools in Peptide and Natural Product Syntheses

(2019) Phil Servatius et al.   SYNLETT

Inert C–H Bond Transformations Enabled by Organometallic Manganese Catalysis

(2018) Yuanyuan Hu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Continuous Visible-Light Photoflow Approach for a Manganese-Catalyzed (Het)Arene C−H Arylation

(2018) Yu-Feng Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

BODIPY Peptide Labeling by Late-Stage C(sp3 )−H Activation

(2018) Wei Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Site-Selective δ-C(sp3 )−H Alkylation of Amino Acids and Peptides with Maleimides via a Six-Membered Palladacycle

(2018) Bei-Bei Zhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Late-Stage Peptide Diversification by Position-Selective C-H Activation

(2018) Wei Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhenium- and Manganese-Catalyzed Selective Alkenylation of Indoles

(2018) Chengming Wang et al.   ChemCatChem

Manganese-Catalyzed Hydrosilylation Reactions

(2018) Xiaoxu Yang et al.   Chemistry-An Asian Journal

Manganese-catalysed benzylic C(sp3)–H amination for late-stage functionalization

(2018) Joseph R. Clark et al.   Nature Chemistry

A general strategy for synthesis of cyclophane-braced peptide macrocycles via palladium-catalysed intramolecular sp3 C−H arylation

(2018) Xuekai Zhang et al.   Nature Chemistry

Manganese Catalyzed Regioselective C–H Alkylation: Experiment and Computation

(2018) Chengming Wang et al.   ORGANIC LETTERS

Manganese(II/III/I)-Catalyzed C–H Arylations in Continuous Flow

(2018) Cuiju Zhu et al.   ACS Catalysis

Palladium(II)-Catalyzed Diastereoselective 2,3-trans C(sp3)-H Arylation of Glycosides

(2018) Nicolas Patrick Probst et al.   ACS Catalysis

Developments in Glycopeptide Antibiotics

(2018) Mark A. T. Blaskovich et al.   ACS Infectious Diseases

Transient Directing Groups for Transformative C–H Activation by Synergistic Metal Catalysis

(2018) Parthasarathy Gandeepan et al.   Chem

Manganese-Catalyzed Redox-Neutral C−H Olefination of Ketones with Unactivated Alkenes

(2018) Yuanyuan Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Backbone-Enabled Directional Peptide Macrocyclization through Late-Stage Palladium-Catalyzed δ-C(sp2 )−H Olefination

(2018) Zengbing Bai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of aryl-thioglycopeptides through chemoselective Pd-mediated conjugation

(2018) David Montoir et al.   Chemical Science

Manganese-catalyzed direct C2-allylation of indoles

(2018) Shang Wu et al.   Organic Chemistry Frontiers

Arylation Chemistry for Bioconjugation

(2018) Bradley Pentelute et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Late-Stage Peptide Diversification through Cobalt-Catalyzed C−H Activation: Sequential Multicatalysis for Stapled Peptides

(2018) Mélanie M. Lorion et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

3d Transition Metals for C–H Activation

(2018) Parthasarathy Gandeepan et al.   CHEMICAL REVIEWS

A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins

(2018) Daniel T. Cohen et al.   Nature Chemistry

Peptide Macrocyclization Inspired by Non-Ribosomal Imine Natural Products

(2017) Lara R. Malins et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Preparation of a Trp-BODIPY fluorogenic amino acid to label peptides for enhanced live-cell fluorescence imaging

(2017) Lorena Mendive-Tapia et al.   Nature Protocols

Intramolecular Pd-Catalyzed Anomeric C(sp3)–H Activation of Glycosyl Carboxamides

(2017) Nicolas Probst et al.   ORGANIC LETTERS

Method development of glycoprotein biomarkers for cancers

(2017) Shuang Yang et al.   Bioanalysis

Aromatic C-H addition of ketones to imines enabled by manganese catalysis

(2017) Bingwei Zhou et al.   Nature Communications

Mild and Regioselective Pd(OAc)2-Catalyzed C–H Arylation of Tryptophans by [ArN2]X, Promoted by Tosic Acid

(2017) Alan J. Reay et al.   ACS Catalysis

C–F/C–H Functionalization by Manganese(I) Catalysis: Expedient (Per)Fluoro-Allylations and Alkenylations

(2017) Daniel Zell et al.   ACS Catalysis

Recent advances in positional-selective alkenylations: removable guidance for twofold C–H activation

(2017) Wenbo Ma et al.   Organic Chemistry Frontiers

From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function

(2017) Peggy Sekula et al.   Scientific Reports

Syntheses and Transformations of α-Amino Acids via Palladium-Catalyzed Auxiliary-Directed sp3 C–H Functionalization

(2016) Gang He et al.   ACCOUNTS OF CHEMICAL RESEARCH

Manganese(I)-Catalyzed C−H Activation: The Key Role of a 7-Membered Manganacycle in H-Transfer and Reductive Elimination

(2016) Nasiru P. Yahaya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Manganese(I)-Catalyzed Substitutive C−H Allylation

(2016) Weiping Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Divergent and Stereoselective Synthesis of β-Silyl-α-Amino Acids through Palladium-Catalyzed Intermolecular Silylation of Unactivated Primary and Secondary C−H Bonds

(2016) Yue-Jin Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Understanding the Chemistry and Biology of Glycosylation with Glycan Synthesis

(2016) Larissa Krasnova et al.   Annual Review of Biochemistry

Palladium-Catalyzed Transformations of Alkyl C–H Bonds

(2016) Jian He et al.   CHEMICAL REVIEWS

Ag-catalyzed C–H/C–C bond functionalization

(2016) Qing-Zhong Zheng et al.   CHEMICAL SOCIETY REVIEWS

Constrained Cyclopeptides: Biaryl Formation through Pd-Catalyzed C−H Activation in Peptides-Structural Control of the Cyclization vs. Cyclodimerization Outcome

(2016) Lorena Mendive-Tapia et al.   CHEMISTRY-A EUROPEAN JOURNAL

Stereoretentive Copper-Catalyzed Directed Thioglycosylation of C(sp2 )−H Bonds of Benzamides

(2016) Amélie Chabrier et al.   CHEMISTRY-A EUROPEAN JOURNAL

Stereoselective Peptide Modifications via β-C(sp3)-H Arylations

(2016) Biplab Mondal et al.   JOURNAL OF ORGANIC CHEMISTRY

Site-Selective Alkenylation of δ-C(sp3)–H Bonds with Alkynes via a Six-Membered Palladacycle

(2016) Jing-Wen Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV

(2016) M Gordon Joyce et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Manganese- and Borane-Mediated Synthesis of Isobenzofuranones from Aromatic Esters and Oxiranes via C–H Bond Activation

(2016) Shunsuke Sueki et al.   ORGANIC LETTERS

Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue

(2016) Lorena Mendive-Tapia et al.   Nature Communications

Manganese-Catalyzed C–H Activation

(2016) Weiping Liu et al.   ACS Catalysis

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV

(2016) M Gordon Joyce et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Bidentate, Monoanionic Auxiliary-Directed Functionalization of Carbon–Hydrogen Bonds

(2015) Olafs Daugulis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chiral Cyclopentadienyls: Enabling Ligands for Asymmetric Rh(III)-Catalyzed C–H Functionalizations

(2015) Baihua Ye et al.   ACCOUNTS OF CHEMICAL RESEARCH

Manganese-Catalyzed Direct Nucleophilic C(sp2)H Addition to Aldehydes and Nitriles

(2015) Bingwei Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Late-Stage Peptide Diversification by Bioorthogonal Catalytic CH Arylation at 23 °C in H2O

(2015) Yingjun Zhu et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Review of Cell Adhesion Studies for Biomedical and Biological Applications

(2015) Amelia Khalili et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ligand-Enabled β-C–H Arylation of α-Amino Acids Using a Simple and Practical Auxiliary

(2015) Gang Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Synthesis of Chiral β-Fluoro α-Amino Acids via Pd(II)-Catalyzed Fluorination of Unactivated Methylene C(sp3)–H Bonds: Scope and Mechanistic Studies

(2015) Qi Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organometallic palladium reagents for cysteine bioconjugation

(2015) Ekaterina V. Vinogradova et al.   NATURE

New peptide architectures through C–H activation stapling between tryptophan–phenylalanine/tyrosine residues

(2015) Lorena Mendive-Tapia et al.   Nature Communications

Amine-accelerated manganese-catalyzed aromatic C–H conjugate addition to α,β-unsaturated carbonyls

(2014) Bingwei Zhou et al.   CHEMICAL COMMUNICATIONS

C–H Functionalization in the Synthesis of Amino Acids and Peptides

(2014) Anaïs F. M. Noisier et al.   CHEMICAL REVIEWS

Chemical and Chemoenzymatic Synthesis of Glycoproteins for Deciphering Functions

(2014) Lai-Xi Wang et al.   CHEMISTRY & BIOLOGY

Late-Stage Diversification of Peptides by Metal-Free CH Arylation

(2014) Yingjun Zhu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Site-Selective C(sp3)–H Functionalization of Di-, Tri-, and Tetrapeptides at the N-Terminus

(2014) Wei Gong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Simply better glycoproteins

(2014) Bernd Lepenies et al.   NATURE BIOTECHNOLOGY

Palladium-Catalyzed Stereoretentive Olefination of Unactivated C(sp3)–H Bonds with Vinyl Iodides at Room Temperature: Synthesis of β-Vinyl α-Amino Acids

(2014) Bo Wang et al.   ORGANIC LETTERS

Regio- and Stereospecific Synthesis of C-3 Functionalized Proline Derivatives by Palladium Catalyzed Directed C(sp3)–H Arylation

(2014) Dominic P. Affron et al.   ORGANIC LETTERS

Ligand-Controlled C(sp3)-H Arylation and Olefination in Synthesis of Unnatural Chiral  -Amino Acids

(2014) J. He et al.   SCIENCE

Palladium-catalyzed trifluoroacetate-promoted mono-arylation of the β-methyl group of alanine at room temperature: synthesis of β-arylated α-amino acids through sequential C–H functionalization

(2014) Bo Wang et al.   Chemical Science

Carboxylate-Assisted Ruthenium-Catalyzed Alkyne Annulations by C–H/Het–H Bond Functionalizations

(2013) Lutz Ackermann   ACCOUNTS OF CHEMICAL RESEARCH

Catalytic Functionalization of C(sp2)H and C(sp3)H Bonds by Using Bidentate Directing Groups

(2013) Guy Rouquet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of C-2 Arylated Tryptophan Amino Acids and Related Compounds through Palladium-Catalyzed C–H Activation

(2013) Sara Preciado et al.   JOURNAL OF ORGANIC CHEMISTRY

Mn-Catalyzed Aromatic C–H Alkenylation with Terminal Alkynes

(2013) Bingwei Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Synthesis of β-Alkylated α-Amino Acids via Palladium-Catalyzed Alkylation of Unactivated Methylene C(sp3)–H Bonds with Primary Alkyl Halides

(2013) Shu-Yu Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C–H bond activation enables the rapid construction and late-stage diversification of functional molecules

(2013) Joanna Wencel-Delord et al.   Nature Chemistry

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

(2013) J. S. McLellan et al.   SCIENCE

Synthetically defined glycoprotein vaccines: current status and future directions

(2013) Roberto Adamo et al.   Chemical Science

Nonnatural Amino Acid Synthesis by Using Carbon-Hydrogen Bond Functionalization Methodology

(2012) Ly Dieu Tran et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

2,5-Diketopiperazines: Synthesis, Reactions, Medicinal Chemistry, and Bioactive Natural Products

(2012) Alan D. Borthwick   CHEMICAL REVIEWS

Vertebrate protein glycosylation: diversity, synthesis and function

(2012) Kelley W. Moremen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Innate and Guided C–H Functionalization Logic

(2011) Tobias Brückl et al.   ACCOUNTS OF CHEMICAL RESEARCH

Production of glycoprotein vaccines in Escherichia coli

(2010) Julian Ihssen et al.   Microbial Cell Factories

Palladium- and Copper-Catalyzed Arylation of Carbon−Hydrogen Bonds

(2009) Olafs Daugulis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Total Synthesis of Celogentin C by Stereoselective CH Activation

(2009) Yiqing Feng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-Metal-Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage

(2009) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins

(2009) Richard J. Payne et al.   CHEMICAL COMMUNICATIONS

Postsynthetic Modification of Peptides: Chemoselective C-Arylation of Tryptophan Residues

(2009) Javier Ruiz-Rodríguez et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of new ribosylated Asn building blocks as useful tools for glycopeptide and glycoprotein synthesis

(2009) M. Angeles Bonache et al.   TETRAHEDRON LETTERS

Glycoprotein Synthesis: An Update

(2008) David P. Gamblin et al.   CHEMICAL REVIEWS

The First Synthesis of N-Man-Trp: Alternative Mannosylation Modification of Protein

(2008) Shino Manabe et al.   SYNLETT