Divergent and Stereoselective Synthesis of β-Silyl-α-Amino Acids through Palladium-Catalyzed Intermolecular Silylation of Unactivated Primary and Secondary C−H Bonds

Syntheses and Transformations of α-Amino Acids via Palladium-Catalyzed Auxiliary-Directed sp3 C–H Functionalization

(2016) Gang He et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis of unnatural amino acids through palladium-catalyzed C(sp3)H functionalization

(2016) Xi Lu et al.   CHINESE CHEMICAL LETTERS

Ruthenium-Catalyzed Intermolecular Direct Silylation of Unreactive C(sp3)–H Bonds

(2016) Wei Li et al.   ORGANIC LETTERS

The mechanism of palladium(II)-mediated C–H cleavage with mono-N-protected amino acid (MPAA) ligands: origins of rate acceleration

(2016) Keary M. Engle   PURE AND APPLIED CHEMISTRY

Undirected, Homogeneous C–H Bond Functionalization: Challenges and Opportunities

(2016) John F. Hartwig et al.   ACS Central Science

Bidentate, Monoanionic Auxiliary-Directed Functionalization of Carbon–Hydrogen Bonds

(2015) Olafs Daugulis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Catalytic Silylation of Unactivated C–H Bonds

(2015) Chen Cheng et al.   CHEMICAL REVIEWS

Stereoselective Synthesis of Chiral β-Fluoro α-Amino Acids via Pd(II)-Catalyzed Fluorination of Unactivated Methylene C(sp3)–H Bonds: Scope and Mechanistic Studies

(2015) Qi Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical synthesis of crystalline proteins

(2015) Yichao Huang et al.   Science China-Chemistry

Sulfonamide-Promoted Palladium(II)-Catalyzed Alkylation of Unactivated Methylene C(sp3)H Bonds with Alkyl Iodides

(2014) Kai Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iridium-Catalyzed Regioselective Silylation of Aromatic and Benzylic CH Bonds Directed by a Secondary Amine

(2014) Qian Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A general and practical palladium-catalyzed monoarylation of β-methyl C(sp3)–H of alanine

(2014) Kai Chen et al.   CHEMICAL COMMUNICATIONS

C–H Functionalization in the Synthesis of Amino Acids and Peptides

(2014) Anaïs F. M. Noisier et al.   CHEMICAL REVIEWS

Iridium-Catalyzed Regioselective Silylation of Secondary Alkyl C–H Bonds for the Synthesis of 1,3-Diols

(2014) Bijie Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-Selective C(sp3)–H Functionalization of Di-, Tri-, and Tetrapeptides at the N-Terminus

(2014) Wei Gong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conversion of 1-alkenes into 1,4-diols through an auxiliary-mediated formal homoallylic C–H oxidation

(2014) Nugzar Ghavtadze et al.   Nature Chemistry

Palladium-Catalyzed Direct C–H Silylation and Germanylation of Benzamides and Carboxamides

(2014) Kyalo Stephen Kanyiva et al.   ORGANIC LETTERS

Ligand-Controlled C(sp3)-H Arylation and Olefination in Synthesis of Unnatural Chiral  -Amino Acids

(2014) J. He et al.   SCIENCE

Palladium-Catalyzed Direct Functionalization of 2-Aminobutanoic Acid Derivatives: Application of a Convenient and Versatile Auxiliary

(2013) Mengyang Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Functionalization of C(sp2)H and C(sp3)H Bonds by Using Bidentate Directing Groups

(2013) Guy Rouquet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iridium- and Rhodium-Catalyzed Dehydrogenative Silylations of C(sp3)H Bonds Adjacent to a Nitrogen Atom Using Hydrosilanes

(2013) Tsuyoshi Mita et al.   Chemistry-An Asian Journal

Developing Ligands for Palladium(II)-Catalyzed C–H Functionalization: Intimate Dialogue between Ligand and Substrate

(2013) Keary M. Engle et al.   JOURNAL OF ORGANIC CHEMISTRY

Stereoselective Synthesis of β-Alkylated α-Amino Acids via Palladium-Catalyzed Alkylation of Unactivated Methylene C(sp3)–H Bonds with Primary Alkyl Halides

(2013) Shu-Yu Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Intramolecular Silylation of Unactivated C(sp3)–H Bonds

(2013) Yoichiro Kuninobu et al.   ORGANIC LETTERS

Pd(ii)-catalyzed alkylation of unactivated C(sp3)–H bonds: efficient synthesis of optically active unnatural α-amino acids

(2013) Kai Chen et al.   Chemical Science

1,2,3-Triazoles as versatile directing group for selective sp2 and sp3 C–H activation: cyclization vs substitution

(2013) Xiaohan Ye et al.   Chemical Science

Synthesis of Aromatic α-Aminoesters: Palladium-Catalyzed Long-Range Arylation of Primary C sp 3H Bonds

(2012) Sam Aspin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonnatural Amino Acid Synthesis by Using Carbon-Hydrogen Bond Functionalization Methodology

(2012) Ly Dieu Tran et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic functionalization of unactivated primary C–H bonds directed by an alcohol

(2012) Eric M. Simmons et al.   NATURE

Sequential Protocol for C(sp3)–H Carboxylation with CO2: Transition-Metal-Catalyzed Benzylic C–H Silylation and Fluoride-Mediated Carboxylation

(2012) Tsuyoshi Mita et al.   ORGANIC LETTERS

Palladium-catalyzed N-(2-pyridyl)sulfonyl-directed C(sp3)–H γ-arylation of amino acid derivatives

(2012) Nuria Rodríguez et al.   Chemical Science

Asymmetric catalytic carbon–carbon coupling reactions via C–H bond activation

(2012) Lei Yang et al.   Catalysis Science & Technology

Borylation and Silylation of C–H Bonds: A Platform for Diverse C–H Bond Functionalizations

(2011) John F. Hartwig   ACCOUNTS OF CHEMICAL RESEARCH

Reactions of Hydrosilanes with Transition Metal Complexes and Characterization of the Products

(2011) Joyce Y. Corey   CHEMICAL REVIEWS

Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope

(2011) Lutz Ackermann   CHEMICAL REVIEWS

Ruthenium-catalyzed C–H Silylation of Methylboronic Acid Using a Removable α-Directing Modifier on the Boron Atom

(2011) Hideki Ihara et al.   CHEMISTRY LETTERS

Challenge and progress: palladium-catalyzed sp3 C–H activation

(2011) Hu Li et al.   Catalysis Science & Technology

Functionalization of Organic Molecules by Transition-Metal-Catalyzed C(sp3)H Activation

(2010) Rodolphe Jazzar et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ligand-Accelerated C−H Activation Reactions: Evidence for a Switch of Mechanism

(2010) Keary M. Engle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Auxiliary-Assisted Palladium-Catalyzed Arylation and Alkylation of sp2and sp3Carbon−Hydrogen Bonds

(2010) Dmitry Shabashov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium- and Copper-Catalyzed Arylation of Carbon−Hydrogen Bonds

(2009) Olafs Daugulis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Total Synthesis of Celogentin C by Stereoselective CH Activation

(2009) Yiqing Feng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and applications of silicon-containing α-amino acids

(2009) Matthew Mortensen et al.   CHEMICAL SOCIETY REVIEWS