The role of the protein–RNA recognition code in neurodegeneration

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Small interfering RNAs based on huntingtin trinucleotide repeats are highly toxic to cancer cells

(2018) Andrea E Murmann et al.   EMBO REPORTS

Towards a complete map of the human long non-coding RNA transcriptome

(2018) Barbara Uszczynska-Ratajczak et al.   NATURE REVIEWS GENETICS

A brave new world of RNA-binding proteins

(2018) Matthias W. Hentze et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex

(2018) Marcello Clerici et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MicroRNA-7 facilitates the degradation of alpha-synuclein and its aggregates by promoting autophagy

(2018) Doo Chul Choi et al.   NEUROSCIENCE LETTERS

Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex

(2018) Marcello Clerici et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alzheimer’s disease hypothesis and related therapies

(2018) Xiaoguang Du et al.   Translational Neurodegeneration

MERIT: Systematic analysis and characterization of Mutational Effect on RNA Interactome Topology

(2018) Yongsheng Li et al.   HEPATOLOGY

The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

(2018) Mathias Munschauer et al.   NATURE

Regulation of microRNA function in animals

(2018) Luca F. R. Gebert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Noncoding RNAs in neurodegeneration

(2017) Evgenia Salta et al.   NATURE REVIEWS NEUROSCIENCE

The role of long non-coding RNAs in rheumatic diseases

(2017) Yuanjia Tang et al.   Nature Reviews Rheumatology

Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington’s disease

(2017) Rocio Gomez-Pastor et al.   Nature Communications

Alterations in mRNA 3′ UTR Isoform Abundance Accompany Gene Expression Changes in Human Huntington’s Disease Brains

(2017) Lindsay Romo et al.   Cell Reports

Structural insights into the assembly and polyA signal recognition mechanism of the human CPSF complex

(2017) Marcello Clerici et al.   eLife

Amyotrophic lateral sclerosis

(2017) Orla Hardiman et al.   Nature Reviews Disease Primers

Serum miR-221 serves as a biomarker for Parkinson's disease

(2016) Wenbin Ma et al.   CELL BIOCHEMISTRY AND FUNCTION

A structural perspective of RNA recognition by intrinsically disordered proteins

(2016) Sushmita Basu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Spinocerebellar ataxia: relationship between phenotype and genotype - a review

(2016) Y.-M. Sun et al.   CLINICAL GENETICS

ZNF384 -related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic immunotype

(2016) Shinsuke Hirabayashi et al.   HAEMATOLOGICA

Atomic Resolution Structure of Monomorphic Aβ42 Amyloid Fibrils

(2016) Michael T. Colvin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

MicroRNA abundance is altered in synaptoneurosomes during prion disease

(2016) Amrit S. Boese et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Comprehensive Identification of RNA-Binding Domains in Human Cells

(2016) Alfredo Castello et al.   MOLECULAR CELL

The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease

(2016) Aaron R. Haeusler et al.   NATURE REVIEWS NEUROSCIENCE

Epigenetic mechanisms in neurogenesis

(2016) Bing Yao et al.   NATURE REVIEWS NEUROSCIENCE

Emerging roles of non-coding RNAs in epigenetic regulation

(2016) Juan Chen et al.   Science China-Life Sciences

Neurodegeneration: From cellular concepts to clinical applications

(2016) A. Katsnelson et al.   Science Translational Medicine

ZNF384 -related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic immunotype

(2016) Shinsuke Hirabayashi et al.   HAEMATOLOGICA

Protein–RNA and protein–glycan recognitions in light of amino acid codes

(2015) Jozef Nahalka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Myotonic dystrophies: An update on clinical aspects, genetic, pathology, and molecular pathomechanisms

(2015) Giovanni Meola et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Amyloid β Protein and Alzheimer’s Disease: When Computer Simulations Complement Experimental Studies

(2015) Jessica Nasica-Labouze et al.   CHEMICAL REVIEWS

Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis

(2015) Paul Childress et al.   MOLECULAR ENDOCRINOLOGY

A naturally occurring variant of the human prion protein completely prevents prion disease

(2015) Emmanuel A. Asante et al.   NATURE

Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1

(2015) Sami J. Barmada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-RNA Interactions Enable Specific Targeting of Noncoding RNAs to Nascent Pre-mRNAs and Chromatin Sites

(2014) Jesse M. Engreitz et al.   CELL

microRNA-9 attenuates amyloidβ-induced synaptotoxicity by targeting calcium/calmodulin-dependent protein kinase kinase 2

(2014) FEI CHANG et al.   Molecular Medicine Reports

Integrating the roles of long and small non-coding RNA in brain function and disease

(2014) G Barry   MOLECULAR PSYCHIATRY

Therapeutic modulation of Notch signalling — are we there yet?

(2014) Emma R. Andersson et al.   NATURE REVIEWS DRUG DISCOVERY

The evolutionary journey of Argonaute proteins

(2014) Daan C Swarts et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Sorting it out: Regulation of exosome loading

(2014) Carolina Villarroya-Beltri et al.   SEMINARS IN CANCER BIOLOGY

A Brief History of Epigenetics

(2014) G. Felsenfeld   Cold Spring Harbor Perspectives in Biology

Genetics of prion diseases

(2013) Sarah E Lloyd et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Protein–RNA recognition: Cracking the code

(2013) Jozef Nahalka   JOURNAL OF THEORETICAL BIOLOGY

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

Influence of microRNA deregulation on chaperone-mediated autophagy and α-synuclein pathology in Parkinson's disease

(2013) L Alvarez-Erviti et al.   Cell Death & Disease

Notch signalling in adult neurons: a potential target for microtubule stabilization

(2013) Sara Anna Bonini et al.   Therapeutic Advances in Neurological Disorders

Structural basis for the protective effect of the human prion protein carrying the dominant-negative E219K polymorphism

(2012) Ivana Biljan et al.   BIOCHEMICAL JOURNAL

Roles for MicroRNAs in Conferring Robustness to Biological Processes

(2012) Margaret S. Ebert et al.   CELL

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

(2012) T. Derrien et al.   GENOME RESEARCH

Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis

(2012) Julien Couthouis et al.   HUMAN MOLECULAR GENETICS

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Quantitative Proteomic Analysis of Human Substantia Nigra in Alzheimer’s Disease, Huntington’s Disease and Multiple Sclerosis

(2012) Sheng Chen et al.   NEUROCHEMICAL RESEARCH

Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells

(2012) Shayne A. Bellingham et al.   NUCLEIC ACIDS RESEARCH

A partially folded structure of amyloid-beta(1–40) in an aqueous environment

(2011) Subramanian Vivekanandan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation

(2011) Tim Bartels et al.   NATURE

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

(2011) Can Liu et al.   NATURE MEDICINE

A role for collagen XXIII in cancer cell adhesion, anchorage-independence and metastasis

(2011) K A Spivey et al.   ONCOGENE

The synaptic pathology of α-synuclein aggregation in dementia with Lewy bodies, Parkinson’s disease and Parkinson’s disease dementia

(2010) Walter J. Schulz-Schaeffer   ACTA NEUROPATHOLOGICA

Rem2 GTPase controls proliferation and apoptosis of neurons during embryo development

(2010) Michael J. Edel et al.   CELL CYCLE

Post-transcriptional Regulation of α-Synuclein Expression by mir-7 and mir-153

(2010) Epaminondas Doxakis   JOURNAL OF BIOLOGICAL CHEMISTRY

Huntington's disease: from molecular pathogenesis to clinical treatment

(2010) Christopher A Ross et al.   LANCET NEUROLOGY

Neuronal MicroRNA Deregulation in Response to Alzheimer's Disease Amyloid-β

(2010) Nicole Schonrock et al.   PLoS One

Non-ATG-initiated translation directed by microsatellite expansions

(2010) T. Zu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease

(2009) Rodrigo A. Quintanilla et al.   BRAIN RESEARCH BULLETIN

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation

(2009) Stefan M.K. Davies et al.   FEBS LETTERS

Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease

(2009) Judith Montag et al.   Molecular Neurodegeneration

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Parkinson's disease: clinical features and diagnosis

(2008) J Jankovic   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY