Notch signalling in adult neurons: a potential target for microtubule stabilization

The Neuroprotective Peptide NAP Does Not Directly Affect Polymerization or Dynamics of Reconstituted Neural Microtubules

(2017) Mythili Yenjerla et al.   JOURNAL OF ALZHEIMERS DISEASE

Brain-penetrant microtubule-stabilizing compounds as potential therapeutic agents for tauopathies: Figure 1

(2012) Kurt R. Brunden et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Microtubule-targeting drugs rescue axonal swellings in cortical neurons from spastin knockout mice

(2012) C. Fassier et al.   Disease Models & Mechanisms

Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria

(2012) G. M. Morotz et al.   HUMAN MOLECULAR GENETICS

The Endocannabinoid, Anandamide, Augments Notch-1 Signaling in Cultured Cortical Neurons Exposed to Amyloid-β and in the Cortex of Aged Rats

(2012) Riffat Tanveer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rho-associated Coiled-coil Kinase (ROCK) Protein Controls Microtubule Dynamics in a Novel Signaling Pathway That Regulates Cell Migration

(2012) Alice V. Schofield et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Microtubule-Stabilizing Agent, Epothilone D, Reduces Axonal Dysfunction, Neurotoxicity, Cognitive Deficits, and Alzheimer-Like Pathology in an Interventional Study with Aged Tau Transgenic Mice

(2012) B. Zhang et al.   JOURNAL OF NEUROSCIENCE

Microtubule Destabilization Is Shared by Genetic and Idiopathic Parkinson’s Disease Patient Fibroblasts

(2012) Daniele Cartelli et al.   PLoS One

Cell-intrinsic signals that regulate adult neurogenesis in vivo: insights from inducible approaches

(2011) Madeleine A. Johnson et al.   BMB Reports

Microtubules (tau) as an Emerging Therapeutic Target: NAP (Davunetide)

(2011) Illana Gozes   CURRENT PHARMACEUTICAL DESIGN

Phase I Trial of MK-0752 in Children With Refractory CNS Malignancies: A Pediatric Brain Tumor Consortium Study

(2011) Maryam Fouladi et al.   JOURNAL OF CLINICAL ONCOLOGY

Nuclear Factor  B-Dependent Neurite Remodeling Is Mediated by Notch Pathway

(2011) S. A. Bonini et al.   JOURNAL OF NEUROSCIENCE

Taxol Facilitates Axon Regeneration in the Mature CNS

(2011) V. Sengottuvel et al.   JOURNAL OF NEUROSCIENCE

A Monoclonal Antibody against Human Notch1 Ligand-Binding Domain Depletes Subpopulation of Putative Breast Cancer Stem-like Cells

(2011) A. Sharma et al.   MOLECULAR CANCER THERAPEUTICS

Rescue of neurons from undergoing hallmark tau-induced Alzheimer's disease cell pathologies by the antimitotic drug paclitaxel

(2011) Or A. Shemesh et al.   NEUROBIOLOGY OF DISEASE

Effect of the neuroprotective peptide davunetide (AL-108) on cognition and functional capacity in schizophrenia

(2011) Daniel C. Javitt et al.   SCHIZOPHRENIA RESEARCH

Identification and validation of Notch pathway activating compounds through a novel high-throughput screening method

(2010) Scott N. Pinchot et al.   CANCER

Microtubule dysfunction precedes transport impairment and mitochondria damage in MPP+-induced neurodegeneration

(2010) Daniele Cartelli et al.   JOURNAL OF NEUROCHEMISTRY

Epothilone D Improves Microtubule Density, Axonal Integrity, and Cognition in a Transgenic Mouse Model of Tauopathy

(2010) K. R. Brunden et al.   JOURNAL OF NEUROSCIENCE

RBPJ -Dependent Signaling Is Essential for Long-Term Maintenance of Neural Stem Cells in the Adult Hippocampus

(2010) O. Ehm et al.   JOURNAL OF NEUROSCIENCE

Alzheimer’s disease and Notch signaling

(2009) Ha-Na Woo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Addressing Alzheimers Disease Tangles: From NAP to AL-108

(2009) Illana Gozes et al.   Current Alzheimer Research

Microtubule-severing enzymes

(2009) Antonina Roll-Mecak et al.   CURRENT OPINION IN CELL BIOLOGY

Notch activation induces neurite remodeling and functional modifications in SH-SY5Y neuronal cells

(2009) Giulia Ferrari-Toninelli et al.   Developmental Neurobiology

Dynamic instability of microtubules requires dynamin 2 and is impaired in a Charcot-Marie-Tooth mutant

(2009) Kenji Tanabe et al.   JOURNAL OF CELL BIOLOGY

Neurogenin 3 cellular and subcellular localization in the developing and adult hippocampus

(2009) Julia Simon-Areces et al.   JOURNAL OF COMPARATIVE NEUROLOGY

An essential role of the aPKC–Aurora A–NDEL1 pathway in neurite elongation by modulation of microtubule dynamics

(2009) Daisuke Mori et al.   NATURE CELL BIOLOGY

The tau of MARK: a polarized view of the cytoskeleton

(2009) Dorthe Matenia et al.   TRENDS IN BIOCHEMICAL SCIENCES

Tubulin modifications and their cellular functions

(2008) Jennetta W Hammond et al.   CURRENT OPINION IN CELL BIOLOGY

Notch: from neural development to neurological disorders

(2008) Justin D. Lathia et al.   JOURNAL OF NEUROCHEMISTRY

The Microtubule-severing Proteins Spastin and Katanin Participate Differently in the Formation of Axonal Branches

(2008) Wenqian Yu et al.   MOLECULAR BIOLOGY OF THE CELL

Microtubule stabilizing effect of notch activation in primary cortical neurons

(2008) G. Ferrari-Toninelli et al.   NEUROSCIENCE

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

(2008) L. M. Ittner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA