Mitochondrial targets of metformin—Are they physiologically relevant?
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Title
Mitochondrial targets of metformin—Are they physiologically relevant?
Authors
Keywords
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Journal
BIOFACTORS
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2019-07-25
DOI
10.1002/biof.1548
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- (2018) Amy R. Cameron et al. Redox Biology
- Molecular Mechanisms of Metformin for Diabetes and Cancer Treatment
- (2018) Min Li et al. Frontiers in Physiology
- Metformin, an Anti-diabetic Drug to Target Leukemia
- (2018) Giulia Biondani et al. Frontiers in Endocrinology
- Low metformin causes a more oxidized mitochondrial NADH/NAD redox state in hepatocytes and inhibits gluconeogenesis by a redox-independent mechanism
- (2018) Ahmed Alshawi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2017) Amanda L. Jackson et al. Oncotarget
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- (2016) Gang Cheng et al. CANCER RESEARCH
- Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin
- (2016) Dan Y. Gui et al. Cell Metabolism
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- (2016) Xiaojing Liu et al. Cell Metabolism
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- (2016) Navdeep S. Chandel et al. Cell Metabolism
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- Metformin Decreases Reactive Oxygen Species, Enhances Osteogenic Properties of Adipose-Derived Multipotent Mesenchymal Stem Cells In Vitro, and Increases Bone Density In Vivo
- (2016) Krzysztof Marycz et al. Oxidative Medicine and Cellular Longevity
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- (2015) Monika Cahova et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Effects of Metformin, Buformin, and Phenformin on the Post-Initiation Stage of Chemically Induced Mammary Carcinogenesis in the Rat
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- (2014) Hannah R. Bridges et al. BIOCHEMICAL JOURNAL
- Serine Deprivation Enhances Antineoplastic Activity of Biguanides
- (2014) S.-P. Gravel et al. CANCER RESEARCH
- Metformin: From Mechanisms of Action to Therapies
- (2014) Marc Foretz et al. Cell Metabolism
- The role of AMPK in controlling metabolism and mitochondrial biogenesis during exercise
- (2014) Katarina Marcinko et al. EXPERIMENTAL PHYSIOLOGY
- Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
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- (2014) William W Wheaton et al. eLife
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- (2012) Tomáš Mráček et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
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- (2011) J. M. Fernández-Real et al. DIABETOLOGIA
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- Dose translation from animal to human studies revisited
- (2007) Shannon Reagan-Shaw et al. FASEB JOURNAL
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