Clinical Pharmacokinetics of Metformin

Functional Characteristics of Two Human MATE Transporters: Kinetics of Cimetidine Transport and Profiles of Iinhibition by Various Compounds

(2016) Kin-ya Ohta et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Benefits and Risks of Oral Diabetes Agents Compared With Insulin in Women With Gestational Diabetes

(2014) Wanda Nicholson et al.   OBSTETRICS AND GYNECOLOGY

Common Variants in 40 Genes Assessed for Diabetes Incidence and Response to Metformin and Lifestyle Intervention in the Diabetes Prevention Program

(2010) K. A. Jablonski et al.   DIABETES

Novel Assay of Metformin Levels in Patients With Type 2 Diabetes and Varying Levels of Renal Function: Clinical recommendations

(2010) A. Frid et al.   DIABETES CARE

Pharmacokinetics of Metformin during Pregnancy

(2010) S. Eyal et al.   DRUG METABOLISM AND DISPOSITION

Organic Cation Transporter 1 Polymorphisms Predict the Metabolic Response to Metformin in Women with the Polycystic Ovary Syndrome

(2010) Alessandra Gambineri et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Potent and Specific Inhibition of mMate1-Mediated Efflux of Type I Organic Cations in the Liver and Kidney by Pyrimethamine

(2010) S. Ito et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine

(2010) Zhi-Jun Wang et al.   Pharmacogenetics and Genomics

Heterozygous variants of multidrug and toxin extrusions (MATE1 and MATE2-K) have little influence on the disposition of metformin in diabetic patients

(2010) Kana Toyama et al.   Pharmacogenetics and Genomics

Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin

(2010) Ligong Chen et al.   Pharmacogenetics and Genomics

A comparison of uptake of metformin and phenformin mediated by hOCT1 in human hepatocytes

(2009) Yoshihisa Sogame et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Current Understanding of the Pharmacogenomics of Metformin

(2009) O Zolk   CLINICAL PHARMACOLOGY & THERAPEUTICS

The Effects of Genetic Polymorphisms in the Organic Cation Transporters OCT1, OCT2, and OCT3 on the Renal Clearance of Metformin

(2009) M V Tzvetkov et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Study of the pharmacokinetic interaction of vildagliptin and metformin in patients with type 2 diabetes

(2009) Yan-Ling He et al.   CURRENT MEDICAL RESEARCH AND OPINION

Reduced-Function SLC22A1 Polymorphisms Encoding Organic Cation Transporter 1 and Glycemic Response to Metformin: A GoDARTS Study

(2009) K. Zhou et al.   DIABETES

Genetic Variation in the Multidrug and Toxin Extrusion 1 Transporter Protein Influences the Glucose-Lowering Effect of Metformin in Patients With Diabetes: A Preliminary Study

(2009) M. L. Becker et al.   DIABETES

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

(2009) Anne T. Nies et al.   HEPATOLOGY

The Case ∣ A suicidal woman with delayed high anion gap metabolic acidosis

(2009) Li-Chun Chang et al.   KIDNEY INTERNATIONAL

Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin

(2009) Ying Chen et al.   Pharmacogenetics and Genomics

Interaction between polymorphisms in the OCT1 and MATE1 transporter and metformin response

(2009) Matthijs L. Becker et al.   Pharmacogenetics and Genomics

Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus

(2009) M L Becker et al.   PHARMACOGENOMICS JOURNAL

Genetic Variants of the Organic Cation Transporter 2 Influence the Disposition of Metformin

(2008) IS Song et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with metformin, pioglitazone and fenofibrate in healthy subjects

(2008) Sujata Vaidyanathan et al.   CURRENT MEDICAL RESEARCH AND OPINION

Effect of food on the pharmacokinetics of a vildagliptin/metformin (50/1000 mg) fixed-dose combination tablet in healthy volunteers

(2008) Yan-Ling He et al.   CURRENT MEDICAL RESEARCH AND OPINION

Metformin, Sulfonylureas, or Other Antidiabetes Drugs and the Risk of Lactic Acidosis or Hypoglycemia: A nested case-control analysis

(2008) M. Bodmer et al.   DIABETES CARE

Metformin and the intestine

(2008) C. J. Bailey et al.   DIABETOLOGIA

The Inhibition of Human Multidrug and Toxin Extrusion 1 Is Involved in the Drug-Drug Interaction Caused by Cimetidine

(2008) S. Matsushima et al.   DRUG METABOLISM AND DISPOSITION

Mechanisms Underlying Saturable Intestinal Absorption of Metformin

(2008) W. R. Proctor et al.   DRUG METABOLISM AND DISPOSITION

Organic Cation Transporters and their Pharmacokinetic and Pharmacodynamic Consequences

(2008) Min-Koo Choi et al.   Drug Metabolism and Pharmacokinetics

Population Exposure-Response Modeling of Metformin in Patients With Type 2 Diabetes Mellitus

(2008) Ying Hong et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Analysis of regulatory polymorphisms in organic ion transporter genes (SLC22A) in the kidney

(2008) Ken Ogasawara et al.   JOURNAL OF HUMAN GENETICS

Structural determinants of inhibitor interaction with the human organic cation transporter OCT2 (SLC22A2)

(2008) Oliver Zolk et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Metformin versus Insulin for the Treatment of Gestational Diabetes

(2008) Janet A. Rowan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Carrier-mediated transport of metformin across the human placenta determined by using theex vivo perfusion of the placental cotyledon model

(2008) Michal Kovo et al.   PRENATAL DIAGNOSIS