Using brain organoids to study human neurodevelopment, evolution and disease
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Title
Using brain organoids to study human neurodevelopment, evolution and disease
Authors
Keywords
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Journal
Wiley Interdisciplinary Reviews-Developmental Biology
Volume -, Issue -, Pages e347
Publisher
Wiley
Online
2019-05-10
DOI
10.1002/wdev.347
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Note: Only part of the references are listed.- Altered neuronal migratory trajectories in human cerebral organoids derived from individuals with neuronal heterotopia
- (2019) Johannes Klaus et al. NATURE MEDICINE
- Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels
- (2018) Adrián Cárdenas et al. CELL
- Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation
- (2018) Ikuo K. Suzuki et al. CELL
- Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis
- (2018) Ian T. Fiddes et al. CELL
- Cerebral organoids derived from Sandhoff disease-induced pluripotent stem cells exhibit impaired neurodifferentiation
- (2018) Maria L. Allende et al. JOURNAL OF LIPID RESEARCH
- Human cerebral organoids reveal deficits in neurogenesis and neuronal migration in MeCP2-deficient neural progenitors
- (2018) N Mellios et al. MOLECULAR PSYCHIATRY
- Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program
- (2018) Marisa Karow et al. NATURE NEUROSCIENCE
- Human brain organoids on a chip reveal the physics of folding
- (2018) Eyal Karzbrun et al. Nature Physics
- Generation of human brain region–specific organoids using a miniaturized spinning bioreactor
- (2018) Xuyu Qian et al. Nature Protocols
- Mob2 Insufficiency Disrupts Neuronal Migration in the Developing Cortex
- (2018) Adam C. O’Neill et al. Frontiers in Cellular Neuroscience
- Differential antiviral immunity to Japanese encephalitis virus in developing cortical organoids
- (2018) Boya Zhang et al. Cell Death & Disease
- Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex
- (2018) Marta Florio et al. eLife
- A novel population of Hopx-dependent basal radial glial cells in the developing mouse neocortex
- (2018) Samir Vaid et al. DEVELOPMENT
- Modeling amyloid beta and tau pathology in human cerebral organoids
- (2018) Cesar Gonzalez et al. MOLECULAR PSYCHIATRY
- Generation and assembly of human brain region–specific three-dimensional cultures
- (2018) Steven A. Sloan et al. Nature Protocols
- Extracellular Matrix Components HAPLN1, Lumican, and Collagen I Cause Hyaluronic Acid-Dependent Folding of the Developing Human Neocortex
- (2018) Katherine R. Long et al. NEURON
- A Primate-Specific Isoform of PLEKHG6 Regulates Neurogenesis and Neuronal Migration
- (2018) Adam C. O’Neill et al. Cell Reports
- Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia
- (2017) Jinsoo Seo et al. JOURNAL OF NEUROSCIENCE
- Assembly of functionally integrated human forebrain spheroids
- (2017) Fikri Birey et al. NATURE
- Cell diversity and network dynamics in photosensitive human brain organoids
- (2017) Giorgia Quadrato et al. NATURE
- Guided self-organization and cortical plate formation in human brain organoids
- (2017) Madeline A Lancaster et al. NATURE BIOTECHNOLOGY
- Fused cerebral organoids model interactions between brain regions
- (2017) Joshua A Bagley et al. NATURE METHODS
- The use of brain organoids to investigate neural development and disease
- (2017) Elizabeth Di Lullo et al. NATURE REVIEWS NEUROSCIENCE
- DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis
- (2017) Fei Ye et al. NEURON
- The Subventricular Zone: A Key Player in Human Neocortical Development
- (2017) J. Alberto Ortega et al. NEUROSCIENTIST
- Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex
- (2017) Tomasz J. Nowakowski et al. SCIENCE
- Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection
- (2017) Momoko Watanabe et al. Cell Reports
- An Organoid-Based Model of Cortical Development Identifies Non-Cell-Autonomous Defects in Wnt Signaling Contributing to Miller-Dieker Syndrome
- (2017) Vira Iefremova et al. Cell Reports
- Recapitulating cortical development with organoid culture in vitro and modeling abnormal spindle-like (ASPM related primary) microcephaly disease
- (2017) Rui Li et al. Protein & Cell
- CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells
- (2017) Ping Wang et al. Molecular Autism
- Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure
- (2016) Xuyu Qian et al. CELL
- 2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size
- (2016) Tomoki Otani et al. Cell Stem Cell
- Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons
- (2016) Junghyun Jo et al. Cell Stem Cell
- Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3
- (2016) Jason Dang et al. Cell Stem Cell
- CPAP promotes timely cilium disassembly to maintain neural progenitor pool
- (2016) Elke Gabriel et al. EMBO JOURNAL
- Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex
- (2016) Lei Wang et al. NATURE NEUROSCIENCE
- Transformation of the Radial Glia Scaffold Demarcates Two Stages of Human Cerebral Cortex Development
- (2016) Tomasz J. Nowakowski et al. NEURON
- CYP3A5 Mediates Effects of Cocaine on Human Neocorticogenesis: Studies using an In Vitro 3D Self-Organized hPSC Model with a Single Cortex-Like Unit
- (2016) Chun-Ting Lee et al. NEUROPSYCHOPHARMACOLOGY
- Zika virus impairs growth in human neurospheres and brain organoids
- (2016) P. P. Garcez et al. SCIENCE
- A restricted period for formation of outer subventricular zone defined by Cdh1 and Trnp1 levels
- (2016) Maria Ángeles Martínez-Martínez et al. Nature Communications
- Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain
- (2016) Chongyuan Luo et al. Cell Reports
- The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice
- (2016) Xiang-Chun Ju et al. eLife
- Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development
- (2016) Felipe Mora-Bermúdez et al. eLife
- Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer’s Disease Phenotypes
- (2016) Waseem K. Raja et al. PLoS One
- FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders
- (2015) Jessica Mariani et al. CELL
- Molecular Identity of Human Outer Radial Glia during Cortical Development
- (2015) Alex A. Pollen et al. CELL
- Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of Astrocytes
- (2015) Giacomo Masserdotti et al. Cell Stem Cell
- Human-Chimpanzee Differences in a FZD8 Enhancer Alter Cell-Cycle Dynamics in the Developing Neocortex
- (2015) J. Lomax Boyd et al. CURRENT BIOLOGY
- Discrete domains of gene expression in germinal layers distinguish the development of gyrencephaly
- (2015) C. de Juan Romero et al. EMBO JOURNAL
- Coevolution of radial glial cells and the cerebral cortex
- (2015) Camino De Juan Romero et al. GLIA
- S-phase duration is the main target of cell cycle regulation in neural progenitors of developing ferret neocortex
- (2015) Miguel Turrero García et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture
- (2015) Anca M Paşca et al. NATURE METHODS
- The Outer Subventricular Zone and Primate-Specific Cortical Complexification
- (2015) Colette Dehay et al. NEURON
- Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
- (2015) M. Florio et al. SCIENCE
- Physical biology of human brain development
- (2015) Silvia Budday et al. Frontiers in Cellular Neuroscience
- Specification of excitatory neurons in the developing cerebral cortex: progenitor diversity and environmental influences
- (2015) Marcos R. Costa et al. Frontiers in Cellular Neuroscience
- Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitors
- (2015) Reuven Edri et al. Nature Communications
- Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue
- (2015) Hideya Sakaguchi et al. Nature Communications
- Self-Organization of Polarized Cerebellar Tissue in 3D Culture of Human Pluripotent Stem Cells
- (2015) Keiko Muguruma et al. Cell Reports
- Neural progenitors, neurogenesis and the evolution of the neocortex
- (2014) M. Florio et al. DEVELOPMENT
- Generation of cerebral organoids from human pluripotent stem cells
- (2014) Madeline A Lancaster et al. Nature Protocols
- An Adaptive Threshold in Mammalian Neocortical Evolution
- (2014) Eric Lewitus et al. PLOS BIOLOGY
- Trnp1 Regulates Expansion and Folding of the Mammalian Cerebral Cortex by Control of Radial Glial Fate
- (2013) Ronny Stahl et al. CELL
- Regulation of cerebral cortex size and folding by expansion of basal progenitors
- (2013) Miki Nonaka-Kinoshita et al. EMBO JOURNAL
- Cerebral organoids model human brain development and microcephaly
- (2013) Madeline A. Lancaster et al. NATURE
- Molecular logic of neocortical projection neuron specification, development and diversity
- (2013) Luciano Custo Greig et al. NATURE REVIEWS NEUROSCIENCE
- Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
- (2013) Yingsha Zhang et al. NEURON
- Precursor Diversity and Complexity of Lineage Relationships in the Outer Subventricular Zone of the Primate
- (2013) Marion Betizeau et al. NEURON
- A cortical folding model incorporating stress-dependent growth explains gyral wavelengths and stress patterns in the developing brain
- (2013) P V Bayly et al. PHYSICAL BIOLOGY
- Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex
- (2013) T. Kadoshima et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Production and organization of neocortical interneurons
- (2013) Khadeejah T. Sultan et al. Frontiers in Cellular Neuroscience
- Amplification of progenitors in the mammalian telencephalon includes a new radial glial cell type
- (2013) Gregor-Alexander Pilz et al. Nature Communications
- Evolution of Human-Specific Neural SRGAP2 Genes by Incomplete Segmental Duplication
- (2012) Megan Y. Dennis et al. CELL
- Emerging roles of neural stem cells in cerebral cortex development and evolution
- (2012) Víctor Borrell et al. Developmental Neurobiology
- Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses
- (2012) Yichen Shi et al. NATURE NEUROSCIENCE
- Abundant Occurrence of Basal Radial Glia in the Subventricular Zone of Embryonic Neocortex of a Lissencephalic Primate, the Common Marmoset Callithrix jacchus
- (2011) Iva Kelava et al. CEREBRAL CORTEX
- Oblique Radial Glial Divisions in the Developing Mouse Neocortex Induce Self-Renewing Progenitors outside the Germinal Zone That Resemble Primate Outer Subventricular Zone Progenitors
- (2011) A. Shitamukai et al. JOURNAL OF NEUROSCIENCE
- Maldevelopment of the cerebral cortex in the surgically induced model of myelomeningocele: implications for fetal neurosurgery
- (2011) Jose L. Encinas et al. JOURNAL OF PEDIATRIC SURGERY
- Generation of Induced Pluripotent Stem Cells from Urine
- (2011) T. Zhou et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- A new subtype of progenitor cell in the mouse embryonic neocortex
- (2011) Xiaoqun Wang et al. NATURE NEUROSCIENCE
- Reprogramming of Human Peripheral Blood Cells to Induced Pluripotent Stem Cells
- (2010) Judith Staerk et al. Cell Stem Cell
- A Role for Intermediate Radial Glia in the Tangential Expansion of the Mammalian Cerebral Cortex
- (2010) Isabel Reillo et al. CEREBRAL CORTEX
- Mechanisms that regulate the number of neurons during mouse neocortical development
- (2010) Takaki Miyata et al. CURRENT OPINION IN NEUROBIOLOGY
- Direct conversion of fibroblasts to functional neurons by defined factors
- (2010) Thomas Vierbuchen et al. NATURE
- Neurogenic radial glia in the outer subventricular zone of human neocortex
- (2010) David V. Hansen et al. NATURE
- OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling
- (2010) Simone A Fietz et al. NATURE NEUROSCIENCE
- Neural Progenitor Nuclei IN Motion
- (2010) Elena Taverna et al. NEURON
- Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
- (2009) Stuart M Chambers et al. NATURE BIOTECHNOLOGY
- Evolution of the neocortex: a perspective from developmental biology
- (2009) Pasko Rakic NATURE REVIEWS NEUROSCIENCE
- Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals
- (2008) Mototsugu Eiraku et al. Cell Stem Cell
- Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage
- (2008) Y. Elkabetz et al. GENES & DEVELOPMENT
- An intrinsic mechanism of corticogenesis from embryonic stem cells
- (2008) Nicolas Gaspard et al. NATURE
- Development of the human cerebral cortex: Boulder Committee revisited
- (2008) Irina Bystron et al. NATURE REVIEWS NEUROSCIENCE
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