CYP3A5 Mediates Effects of Cocaine on Human Neocorticogenesis: Studies using an In Vitro 3D Self-Organized hPSC Model with a Single Cortex-Like Unit

High-Content Assay Multiplexing for Toxicity Screening in Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Hepatocytes

(2015) Fabian Alexander Grimm et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Early-Course Unmedicated Schizophrenia Patients Exhibit Elevated Prefrontal Connectivity Associated with Longitudinal Change

(2015) A. Anticevic et al.   JOURNAL OF NEUROSCIENCE

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

(2015) Anca M Paşca et al.   NATURE METHODS

A new technique for modeling neuronal connectivity using human pluripotent stem cells

(2015) Chun-Ting Lee et al.   RESTORATIVE NEUROLOGY AND NEUROSCIENCE

CNVs in neurodevelopmental disorders

(2015) Chun-Ting Lee et al.   Oncotarget

Functional Consequences of 17q21.31/WNT3-WNT9B Amplification in hPSCs with Respect to Neural Differentiation

(2015) Chun-Ting Lee et al.   Cell Reports

An in vitro model of human neocortical development using pluripotent stem cells: cocaine-induced cytoarchitectural alterations

(2014) A. A. Kindberg et al.   Disease Models & Mechanisms

Patches of Disorganization in the Neocortex of Children with Autism

(2014) Rich Stoner et al.   NEW ENGLAND JOURNAL OF MEDICINE

Aggregate Culture of Human Embryonic Stem Cell-Derived Hepatocytes in Suspension Are an Improved In Vitro Model for Drug Metabolism and Toxicity Testing

(2014) Srikumar Sengupta et al.   TOXICOLOGICAL SCIENCES

Prenatal Cocaine Exposure and Gray Matter Volume in Adolescent Boys and Girls: Relationship to Substance Use Initiation

(2013) Kenneth Rando et al.   BIOLOGICAL PSYCHIATRY

Structural and molecular interrogation of intact biological systems

(2013) Kwanghun Chung et al.   NATURE

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Human pluripotent stem cell models of autism spectrum disorder: emerging frontiers, opportunities, and challenges towards neuronal networks in a dish

(2013) Stefan Aigner et al.   PSYCHOPHARMACOLOGY

Contribution of Oxidative Metabolism to Cocaine-Induced Liver and Kidney Damage

(2012) M.J. Valente et al.   CURRENT MEDICINAL CHEMISTRY

Modeling psychiatric disorders at the cellular and network levels

(2012) K J Brennand et al.   MOLECULAR PSYCHIATRY

StemCellDB: The Human Pluripotent Stem Cell Database at the National Institutes of Health

(2012) Barbara S. Mallon et al.   Stem Cell Research

FGF signalling inhibits neural induction in human embryonic stem cells

(2011) Boris Greber et al.   EMBO JOURNAL

Neuron Number and Size in Prefrontal Cortex of Children With Autism

(2011) Eric Courchesne et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Modelling schizophrenia using human induced pluripotent stem cells

(2011) Kristen J. Brennand et al.   NATURE

Estimated effects of in utero cocaine exposure on language development through early adolescence

(2011) Emmalee S. Bandstra et al.   NEUROTOXICOLOGY AND TERATOLOGY

Cocaine causes deficits in radial migration and alters the distribution of glutamate and GABA neurons in the developing rat cerebral cortex

(2010) Chun-Ting Lee et al.   SYNAPSE

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Evolution of the neocortex: a perspective from developmental biology

(2009) Pasko Rakic   NATURE REVIEWS NEUROSCIENCE

Withdrawal from Cocaine Self-Administration Normalizes Deficits in Proliferation and Enhances Maturity of Adult-Generated Hippocampal Neurons

(2008) M. A. Noonan et al.   JOURNAL OF NEUROSCIENCE

Prenatal Cocaine Exposure: Drug and Environmental Effects at 9 Years

(2008) Lynn T. Singer et al.   JOURNAL OF PEDIATRICS

Drug Metabolism in Human Brain: High Levels of Cytochrome P4503A43 in Brain and Metabolism of Anti-Anxiety Drug Alprazolam to Its Active Metabolite

(2008) Varsha Agarwal et al.   PLoS One

A Mechanism for the Inhibition of Neural Progenitor Cell Proliferation by Cocaine

(2008) Chun-Ting Lee et al.   PLOS MEDICINE