Generation and assembly of human brain region–specific three-dimensional cultures

Assembly of functionally integrated human forebrain spheroids

(2017) Fikri Birey et al.   NATURE

Fused cerebral organoids model interactions between brain regions

(2017) Joshua A Bagley et al.   NATURE METHODS

The use of brain organoids to investigate neural development and disease

(2017) Elizabeth Di Lullo et al.   NATURE REVIEWS NEUROSCIENCE

Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells

(2017) Steven A. Sloan et al.   NEURON

Personalized Human Cortical Spheroids

(2016) Sergiu P. Paşca   AMERICAN JOURNAL OF PSYCHIATRY

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

(2016) Xuyu Qian et al.   CELL

Stem Cell Models of Human Brain Development

(2016) Iva Kelava et al.   Cell Stem Cell

Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain

(2016) Benjamin E Deverman et al.   NATURE BIOTECHNOLOGY

The promises and challenges of human brain organoids as models of neuropsychiatric disease

(2016) Giorgia Quadrato et al.   NATURE MEDICINE

The Cellular and Molecular Landscapes of the Developing Human Central Nervous System

(2016) John C. Silbereis et al.   NEURON

Extensive migration of young neurons into the infant human frontal lobe

(2016) M. F. Paredes et al.   SCIENCE

A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients

(2016) Yishan Sun et al.   eLife

FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders

(2015) Jessica Mariani et al.   CELL

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

(2015) Anca M Paşca et al.   NATURE METHODS

Self-Organization of Polarized Cerebellar Tissue in 3D Culture of Human Pluripotent Stem Cells

(2015) Keiko Muguruma et al.   Cell Reports

Generating Human Neurons In Vitro and Using Them to Understand Neuropsychiatric Disease

(2014) Sergiu P. Paşca et al.   Annual Review of Neuroscience

Mechanisms of astrocyte development and their contributions to neurodevelopmental disorders

(2014) Steven A Sloan et al.   CURRENT OPINION IN NEUROBIOLOGY

Synaptic dysregulation in a human iPS cell model of mental disorders

(2014) Zhexing Wen et al.   NATURE

Interneuron cell types are fit to function

(2014) Adam Kepecs et al.   NATURE

Pluripotent stem cells in regenerative medicine: challenges and recent progress

(2014) Viviane Tabar et al.   NATURE REVIEWS GENETICS

Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome

(2014) Yuan Tian et al.   Genome Medicine

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Subcortical origins of human and monkey neocortical interneurons

(2013) Tong Ma et al.   NATURE NEUROSCIENCE

Evolving Concepts of Gliogenesis: A Look Way Back and Ahead to the Next 25 Years

(2013) Marc R. Freeman et al.   NEURON

Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex

(2013) T. Kadoshima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling psychiatric disorders at the cellular and network levels

(2012) K J Brennand et al.   MOLECULAR PSYCHIATRY

Interneuron dysfunction in psychiatric disorders

(2012) Oscar Marín   NATURE REVIEWS NEUROSCIENCE

The Human Brain in a Dish: The Promise of iPSC-Derived Neurons

(2011) Ricardo Dolmetsch et al.   CELL

Modeling psychiatric disorders through reprogramming

(2011) K. J. Brennand et al.   Disease Models & Mechanisms

Modelling schizophrenia using human induced pluripotent stem cells

(2011) Kristen J. Brennand et al.   NATURE

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

(2011) Sergiu P Paşca et al.   NATURE MEDICINE

A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

(2010) Maria C.N. Marchetto et al.   CELL

The Basics of Brain Development

(2010) Joan Stiles et al.   NEUROPSYCHOLOGY REVIEW

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs

(2009) Gabsang Lee et al.   NATURE

Lentivirus Production

(2009) Xiaoyin Wang et al.   Jove-Journal of Visualized Experiments

Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals

(2008) Mototsugu Eiraku et al.   Cell Stem Cell