Genome-wide association study of medication-use and associated disease in the UK Biobank
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Title
Genome-wide association study of medication-use and associated disease in the UK Biobank
Authors
Keywords
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Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Nature
Online
2019-04-23
DOI
10.1038/s41467-019-09572-5
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Note: Only part of the references are listed.- Self-reported medication use validated through record linkage to national prescribing data
- (2018) Jonathan D. Hafferty et al. JOURNAL OF CLINICAL EPIDEMIOLOGY
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- (2018) Po-Ru Loh et al. NATURE GENETICS
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- (2018) Hilary K. Finucane et al. NATURE GENETICS
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- (2018) Zhihong Zhu et al. Nature Communications
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- (2018) Clare Bycroft et al. NATURE
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- (2017) Louise V. Wain et al. HYPERTENSION
- Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks
- (2017) Florence Demenais et al. NATURE GENETICS
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- (2017) Helen R Warren et al. NATURE GENETICS
- The mucosal immune system: master regulator of bidirectional gut–brain communications
- (2017) Nick Powell et al. Nature Reviews Gastroenterology & Hepatology
- Tezepelumab in Adults with Uncontrolled Asthma
- (2017) Jonathan Corren et al. NEW ENGLAND JOURNAL OF MEDICINE
- The druggable genome and support for target identification and validation in drug development
- (2017) Chris Finan et al. Science Translational Medicine
- Unexplained Painful Physical Symptoms in Patients with Major Depressive Disorder: Prevalence, Pathophysiology and Management
- (2016) Jan Jaracz et al. CNS DRUGS
- An Integrative Review on Role and Mechanisms of Ghrelin in Stress, Anxiety and Depression
- (2016) Anjana Bali et al. CURRENT DRUG TARGETS
- Treatment Indications for Antidepressants Prescribed in Primary Care in Quebec, Canada, 2006-2015
- (2016) Jenna Wong et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Genome-wide association study identifies 74 loci associated with educational attainment
- (2016) Aysu Okbay et al. NATURE
- Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses
- (2016) Aysu Okbay et al. NATURE GENETICS
- Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
- (2016) Zhihong Zhu et al. NATURE GENETICS
- A comprehensive map of molecular drug targets
- (2016) Rita Santos et al. NATURE REVIEWS DRUG DISCOVERY
- The statistical properties of gene-set analysis
- (2016) Christiaan A. de Leeuw et al. NATURE REVIEWS GENETICS
- The ChEMBL database in 2017
- (2016) Anna Gaulton et al. NUCLEIC ACIDS RESEARCH
- The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)
- (2016) Jacqueline MacArthur et al. NUCLEIC ACIDS RESEARCH
- Commonly prescribed drugs associate with cognitive function: a cross-sectional study in UK Biobank
- (2016) Alejo J Nevado-Holgado et al. BMJ Open
- BMI and BMD: The Potential Interplay between Obesity and Bone Fragility
- (2016) Andrea Palermo et al. International Journal of Environmental Research and Public Health
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- (2015) Adam E. Locke et al. NATURE
- Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture
- (2015) Hou‐Feng Zheng et al. NATURE
- The support of human genetic evidence for approved drug indications
- (2015) Matthew R Nelson et al. NATURE GENETICS
- An atlas of genetic correlations across human diseases and traits
- (2015) Brendan Bulik-Sullivan et al. NATURE GENETICS
- Gene expression analysis identifies global gene dosage sensitivity in cancer
- (2015) Rudolf S N Fehrmann et al. NATURE GENETICS
- LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
- (2015) Brendan K Bulik-Sullivan et al. NATURE GENETICS
- The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
- (2015) et al. SCIENCE
- MAGMA: Generalized Gene-Set Analysis of GWAS Data
- (2015) Christiaan A. de Leeuw et al. PLoS Computational Biology
- UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
- (2015) Cathie Sudlow et al. PLOS MEDICINE
- Second-generation PLINK: rising to the challenge of larger and richer datasets
- (2015) Christopher C Chang et al. GigaScience
- The Molecular Signatures Database Hallmark Gene Set Collection
- (2015) Arthur Liberzon et al. Cell Systems
- Human symptoms–disease network
- (2014) XueZhong Zhou et al. Nature Communications
- Genetics of rheumatoid arthritis contributes to biology and drug discovery
- (2013) Yukinori Okada et al. NATURE
- Discovery and refinement of loci associated with lipid levels
- (2013) Cristen J Willer et al. NATURE GENETICS
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- (2013) Harm-Jan Westra et al. NATURE GENETICS
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- (2012) NATURE GENETICS
- Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
- (2012) Jian Yang et al. NATURE GENETICS
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- (2011) Xavier Robin et al. BMC BIOINFORMATICS
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- (2011) Georg B. Ehret et al. NATURE
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- (2011) Heribert Schunkert et al. NATURE GENETICS
- Reengineering Translational Science: The Time Is Right
- (2011) F. S. Collins Science Translational Medicine
- GCTA: A Tool for Genome-wide Complex Trait Analysis
- (2010) Jian Yang et al. AMERICAN JOURNAL OF HUMAN GENETICS
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- (2010) NATURE GENETICS
- Defining Comorbidity: Implications for Understanding Health and Health Services
- (2009) J. M. Valderas et al. ANNALS OF FAMILY MEDICINE
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- (2008) Michael Lutter et al. NATURE NEUROSCIENCE
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