The statistical properties of gene-set analysis

Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions

(2015) David C. Qian et al.   HUMAN MOLECULAR GENETICS

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

Biological interpretation of genome-wide association studies using predicted gene functions

(2015) Tune H. Pers et al.   Nature Communications

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Functional and genomic context in pathway analysis of GWAS data

(2014) Michael A. Mooney et al.   TRENDS IN GENETICS

Identification of Pathways for Bipolar Disorder

(2014) John I. Nurnberger et al.   JAMA Psychiatry

Network-assisted analysis to prioritize GWAS results: principles, methods and perspectives

(2013) Peilin Jia et al.   HUMAN GENETICS

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

(2013) Stephan Ripke et al.   NATURE GENETICS

Bringing genome-wide association findings into clinical use

(2013) Teri A. Manolio   NATURE REVIEWS GENETICS

The Reactome pathway knowledgebase

(2013) David Croft et al.   NUCLEIC ACIDS RESEARCH

Methods and approaches in the topology-based analysis of biological pathways

(2013) Cristina Mitrea et al.   Frontiers in Physiology

HYST: A Hybrid Set-Based Test for Genome-wide Association Studies, with Application to Protein-Protein Interaction-Based Association Analysis

(2012) Miao-Xin Li et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Five Years of GWAS Discovery

(2012) Peter M. Visscher et al.   AMERICAN JOURNAL OF HUMAN GENETICS

INRICH: interval-based enrichment analysis for genome-wide association studies

(2012) Phil H. Lee et al.   BIOINFORMATICS

Common Genetic Variants and Gene-Expression Changes Associated with Bipolar Disorder Are Over-Represented in Brain Signaling Pathway Genes

(2012) Inti Pedroso et al.   BIOLOGICAL PSYCHIATRY

Genetic architectures of psychiatric disorders: the emerging picture and its implications

(2012) Patrick F. Sullivan et al.   NATURE REVIEWS GENETICS

Comparison of Methods for Competitive Tests of Pathway Analysis

(2012) Marina Evangelou et al.   PLoS One

Evaluation of an approximation method for assessment of overall significance of multiple-dependent tests in a genomewide association study

(2011) Valentina Moskvina et al.   GENETIC EPIDEMIOLOGY

Gene set analysis of genome-wide association studies: Methodological issues and perspectives

(2011) Lily Wang et al.   GENOMICS

Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways

(2011) Hariklia Eleftherohorinou et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies five new schizophrenia loci

(2011)   NATURE GENETICS

Pathway analysis comparison using Crohn's disease genome wide association studies

(2010) David Ballard et al.   BMC Medical Genomics

Pathway Analysis of Breast Cancer Genome-Wide Association Study Highlights Three Pathways and One Canonical Signaling Cascade

(2010) Idan Menashe et al.   CANCER RESEARCH

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Analysing biological pathways in genome-wide association studies

(2010) Kai Wang et al.   NATURE REVIEWS GENETICS

Genomewide Association Studies and Assessment of the Risk of Disease

(2010) Teri A. Manolio   NEW ENGLAND JOURNAL OF MEDICINE

Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits

(2010) Ayellet V. Segrè et al.   PLoS Genetics

Gene Ontology Analysis of GWA Study Data Sets Provides Insights into the Biology of Bipolar Disorder

(2009) Peter Holmans et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease

(2009) Kai Wang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The SNP ratio test: pathway analysis of genome-wide association datasets

(2009) Colm O'Dushlaine et al.   BIOINFORMATICS

Using genome-wide pathway analysis to unravel the etiology of complex diseases

(2009) Clara C. Elbers et al.   GENETIC EPIDEMIOLOGY

Pathways-based analyses of whole-genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission

(2008) Kathleen Askland et al.   HUMAN GENETICS