The Role of Complement C3a Receptor in Stroke

Complement activation contributes to perioperative neurocognitive disorders in mice

(2018) Chao Xiong et al.   Journal of Neuroinflammation

Tissue plasminogen activator-based nanothrombolysis for ischemic stroke

(2017) Shan Liu et al.   Expert Opinion on Drug Delivery

Complement in the pathogenesis of Alzheimer’s disease

(2017) B. Paul Morgan   Seminars in Immunopathology

Neuronal survival in the brain: neuron type-specific mechanisms

(2017) Ulrich Pfisterer et al.   Cell Death & Disease

Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a

(2017) Rink-Jan Lohman et al.   Nature Communications

Tissue plasminogen activator mediates deleterious complement cascade activation in stroke

(2017) Xue-Jun Zhao et al.   PLoS One

Complement peptide C3a stimulates neural plasticity after experimental brain ischaemia

(2016) Anna Stokowska et al.   BRAIN

The Indispensable Roles of Microglia and Astrocytes during Brain Development

(2016) Kitty Reemst et al.   Frontiers in Human Neuroscience

Properdin: a tightly regulated critical inflammatory modulator

(2016) Adam Z. Blatt et al.   IMMUNOLOGICAL REVIEWS

Inflammatory Response in the CNS: Friend or Foe?

(2016) Marta Sochocka et al.   MOLECULAR NEUROBIOLOGY

A complement–microglial axis drives synapse loss during virus-induced memory impairment

(2016) Michael J. Vasek et al.   NATURE

The Blood–Brain Barrier

(2015) Richard Daneman et al.   Cold Spring Harbor Perspectives in Biology

Complement System Part I – Molecular Mechanisms of Activation and Regulation

(2015) Nicolas S. Merle et al.   Frontiers in Immunology

Pathogens Penetrating the Central Nervous System: Infection Pathways and the Cellular and Molecular Mechanisms of Invasion

(2014) Samantha J. Dando et al.   CLINICAL MICROBIOLOGY REVIEWS

Complement and blood–brain barrier integrity

(2014) Alexander Jacob et al.   MOLECULAR IMMUNOLOGY

Receptor for complement peptide C3a: a therapeutic target for neonatal hypoxic-ischemic brain injury

(2013) Katarina Järlestedt et al.   FASEB JOURNAL

Overview of Complement Activation and Regulation

(2013) Marina Noris et al.   SEMINARS IN NEPHROLOGY

Complement Inhibition Promotes Endogenous Neurogenesis and Sustained Anti-Inflammatory Neuroprotection following Reperfused Stroke

(2012) Andrew F. Ducruet et al.   PLoS One

Complement 3 and Factor H in Human Cerebrospinal Fluid in Parkinson's Disease, Alzheimer's Disease, and Multiple-System Atrophy

(2011) Yu Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Complement upregulation and activation on motor neurons and neuromuscular junction in the SOD1 G93A mouse model of familial amyotrophic lateral sclerosis

(2011) Bianca Heurich et al.   JOURNAL OF NEUROIMMUNOLOGY

Complement in the brain

(2011) Robert Veerhuis et al.   MOLECULAR IMMUNOLOGY

Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

(2011) Trent M Woodruff et al.   Molecular Neurodegeneration

The Potential of Tetrandrine as a Protective Agent for Ischemic Stroke

(2011) Yun Chen et al.   MOLECULES

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Complement in neuroprotection and neurodegeneration

(2010) Vijay Yanamadala et al.   TRENDS IN MOLECULAR MEDICINE

The complement cascade as a therapeutic target in intracerebral hemorrhage

(2009) Andrew F. Ducruet et al.   EXPERIMENTAL NEUROLOGY

The Role of the Complement System and the Activation Fragment C5a in the Central Nervous System

(2009) Trent M. Woodruff et al.   NEUROMOLECULAR MEDICINE

Complement-Derived Anaphylatoxin C3a Regulates In Vitro Differentiation and Migration of Neural Progenitor Cells

(2009) Noriko Shinjyo et al.   STEM CELLS

Tissue-type plasminogen activator as a therapeutic target in stroke

(2008) Iordanis Gravanis et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

C3a Receptor Modulation of Granulocyte Infiltration after Murine Focal Cerebral Ischemia is Reperfusion Dependent

(2008) Andrew F Ducruet et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroprotection in stroke by complement inhibition and immunoglobulin therapy

(2008) T.V. Arumugam et al.   NEUROSCIENCE