Metabolic control of BRISC–SHMT2 assembly regulates immune signalling

HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2

(2019) Ji Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pseudo-DUBs as allosteric activators and molecular scaffolds of protein complexes

(2018) Miriam Walden et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity

(2018) Joshua D. Ochocki et al.   Cell Metabolism

A Completely Reimplemented MPI Bioinformatics Toolkit with a New HHpred Server at its Core

(2018) Lukas Zimmermann et al.   JOURNAL OF MOLECULAR BIOLOGY

Collection, pre-processing and on-the-fly analysis of data for high-resolution, single-particle cryo-electron microscopy

(2018) Rebecca F. Thompson et al.   Nature Protocols

Deacetylation of serine hydroxymethyl-transferase 2 by SIRT3 promotes colorectal carcinogenesis

(2018) Zhen Wei et al.   Nature Communications

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

cAMP-dependent protein kinase (PKA) complexes probed by complementary differential scanning fluorimetry and ion mobility-mass spectrometry

(2016) D. P. Byrne et al.   BIOCHEMICAL JOURNAL

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

High-resolution mass spectrometry of small molecules bound to membrane proteins

(2016) Joseph Gault et al.   NATURE METHODS

Three-Dimensional Architecture of the Human BRCA1-A Histone Deubiquitinase Core Complex

(2016) Otto J.P. Kyrieleis et al.   Cell Reports

Bayesian Deconvolution of Mass and Ion Mobility Spectra: From Binary Interactions to Polydisperse Ensembles

(2015) Michael T. Marty et al.   ANALYTICAL CHEMISTRY

How pyridoxal 5′-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state

(2015) Giorgio Giardina et al.   FEBS Journal

MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links

(2015) Qinqin Jiang et al.   GENES & DEVELOPMENT

Examination of Ataxin-3 (atx-3) Aggregation by Structural Mass Spectrometry Techniques: A Rationale for Expedited Aggregation upon Polyglutamine (polyQ) Expansion

(2015) Charlotte A. Scarff et al.   MOLECULAR & CELLULAR PROTEOMICS

Higher-Order Assembly of BRCC36–KIAA0157 Is Required for DUB Activity and Biological Function

(2015) Elton Zeqiraj et al.   MOLECULAR CELL

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

FFAS-3D: improving fold recognition by including optimized structural features and template re-ranking

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A BRISC-SHMT Complex Deubiquitinates IFNAR1 and Regulates Interferon Responses

(2013) Hui Zheng et al.   Cell Reports

Serine Hydroxymethyltransferase Anchorsde NovoThymidylate Synthesis Pathway to Nuclear Lamina for DNA Synthesis

(2012) Donald D. Anderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-sensitivity Orbitrap mass analysis of intact macromolecular assemblies

(2012) Rebecca J Rose et al.   NATURE METHODS

Structural Basis and Sequence Rules for Substrate Recognition by Tankyrase Explain the Basis for Cherubism Disease

(2011) Sebastian Guettler et al.   CELL

NBA1/MERIT40 and BRE Interaction Is Required for the Integrity of Two Distinct Deubiquitinating Enzyme BRCC36-containing Complexes

(2011) Xin Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

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Differential Regulation of JAMM Domain Deubiquitinating Enzyme Activity within the RAP80 Complex

(2010) Jeffrey Patterson-Fortin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Lys63-specific Deubiquitinating Enzyme BRCC36 Is Regulated by Two Scaffold Proteins Localizing in Different Subcellular Compartments

(2010) Lin Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Defining the Human Deubiquitinating Enzyme Interaction Landscape

(2009) Mathew E. Sowa et al.   CELL

MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks

(2009) G. Shao et al.   GENES & DEVELOPMENT

Specificity of the BRISC Deubiquitinating Enzyme Is Not Due to Selective Binding to Lys63-linked Polyubiquitin

(2009) Eric M. Cooper et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis

(2008) Garth Hamilton et al.   EMBO JOURNAL