Collection, pre-processing and on-the-fly analysis of data for high-resolution, single-particle cryo-electron microscopy

Cryo-EM in drug discovery: achievements, limitations and prospects

(2018) Jean-Paul Renaud et al.   NATURE REVIEWS DRUG DISCOVERY

Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM

(2018) Shaun Rawson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Structure of an Infectious Human Polyomavirus and Its Interactions with Cellular Receptors

(2018) Daniel L. Hurdiss et al.   STRUCTURE

The 3.3 Å structure of a plant geminivirus using cryo-EM

(2018) Emma L. Hesketh et al.   Nature Communications

Approaches to altering particle distributions in cryo-electron microscopy sample preparation

(2018) Ieva Drulyte et al.   Acta Crystallographica Section D-Structural Biology

X-ray and cryo-EM structures of inhibitor-bound cytochrome bc 1 complexes for structure-based drug discovery

(2018) Kangsa Amporndanai et al.   IUCrJ

Prespliceosome structure provides insights into spliceosome assembly and regulation

(2018) Clemens Plaschka et al.   NATURE

The structure of a β2-microglobulin fibril suggests a molecular basis for its amyloid polymorphism

(2018) Matthew G. Iadanza et al.   Nature Communications

Focus: The interface between data collection and data processing in cryo-EM

(2017) Nikhil Biyani et al.   JOURNAL OF STRUCTURAL BIOLOGY

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Addressing preferred specimen orientation in single-particle cryo-EM through tilting

(2017) Yong Zi Tan et al.   NATURE METHODS

Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus

(2017) Jim Baggen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A pipeline approach to single-particle processing inRELION

(2017) Rafael Fernandez-Leiro et al.   Acta Crystallographica Section D-Structural Biology

Trends in the Electron Microscopy Data Bank (EMDB)

(2017) Ardan Patwardhan   Acta Crystallographica Section D-Structural Biology

Scipion: A software framework toward integration, reproducibility and validation in 3D electron microscopy

(2016) J.M. de la Rosa-Trevín et al.   JOURNAL OF STRUCTURAL BIOLOGY

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

An introduction to sample preparation and imaging by cryo-electron microscopy for structural biology

(2016) Rebecca F. Thompson et al.   METHODS

A Primer to Single-Particle Cryo-Electron Microscopy

(2015) Yifan Cheng et al.   CELL

FEI’s direct electron detector developments: Embarking on a revolution in cryo-TEM

(2015) Maarten Kuijper et al.   JOURNAL OF STRUCTURAL BIOLOGY

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6

(2015) Timothy Grant et al.   eLife

Volta potential phase plate for in-focus phase contrast transmission electron microscopy

(2014) R. Danev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrastable gold substrates for electron cryomicroscopy

(2014) C. J. Russo et al.   SCIENCE

The Resolution Revolution

(2014) W. Kuhlbrandt   SCIENCE

Comparison of optimal performance at 300keV of three direct electron detectors for use in low dose electron microscopy

(2014) G. McMullan et al.   ULTRAMICROSCOPY

Quantitative characterization of electron detectors for transmission electron microscopy

(2013) Rachel S. Ruskin et al.   JOURNAL OF STRUCTURAL BIOLOGY

A Bayesian View on Cryo-EM Structure Determination

(2011) Sjors H.W. Scheres   JOURNAL OF MOLECULAR BIOLOGY