Differential Regulation of JAMM Domain Deubiquitinating Enzyme Activity within the RAP80 Complex

ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks

(2010) Niraj M. Shanbhag et al.   CELL

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

(2009) Grant S. Stewart et al.   CELL

K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1

(2009) Eric M Cooper et al.   EMBO JOURNAL

MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks

(2009) G. Shao et al.   GENES & DEVELOPMENT

MERIT40 facilitates BRCA1 localization and DNA damage repair

(2009) L. Feng et al.   GENES & DEVELOPMENT

NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control

(2009) B. Wang et al.   GENES & DEVELOPMENT

Specificity of the BRISC Deubiquitinating Enzyme Is Not Due to Selective Binding to Lys63-linked Polyubiquitin

(2009) Eric M. Cooper et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ubiquitin landscape at DNA double-strand breaks

(2009) Troy E. Messick et al.   JOURNAL OF CELL BIOLOGY

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

(2009) Simon Bekker-Jensen et al.   NATURE CELL BIOLOGY

Breaking the chains: structure and function of the deubiquitinases

(2009) David Komander et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Familial breast cancer screening reveals an alteration in the RAP80 UIM domain that impairs DNA damage response function

(2009) J Nikkilä et al.   ONCOGENE

The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubc13-dependent ubiquitination events at DNA double strand breaks

(2009) G. Shao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition of DNA double strand breaks by the BRCA1 tumor suppressor network

(2008) Roger A. Greenberg   CHROMOSOMA

Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains

(2008) Yusuke Sato et al.   NATURE

Genome instability: a mechanistic view of its causes and consequences

(2008) Andrés Aguilera et al.   NATURE REVIEWS GENETICS