The role of extracellular vesicles from different origin in the microenvironment of head and neck cancers

Tumor-derived extracellular vesicles in angiogenesis

(2018) Wei Song et al.   BIOMEDICINE & PHARMACOTHERAPY

Salivary extracellular vesicle-associated miRNAs as potential biomarkers in oral squamous cell carcinoma

(2018) Chiara Gai et al.   BMC CANCER

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

New Technologies for Analysis of Extracellular Vesicles

(2018) Huilin Shao et al.   CHEMICAL REVIEWS

Liquid Biopsy in Oral Cancer

(2018) Fatima Lousada-Fernandez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

HSP-enriched properties of extracellular vesicles involve survival of metastatic oral cancer cells

(2018) Kisho Ono et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Proteomic Analysis of Cancer-Associated Fibroblasts Reveals a Paracrine Role for MFAP5 in Human Oral Tongue Squamous Cell Carcinoma

(2018) Simona Principe et al.   JOURNAL OF PROTEOME RESEARCH

Hypoxic Lung-Cancer-Derived Extracellular Vesicle MicroRNA-103a Increases the Oncogenic Effects of Macrophages by Targeting PTEN

(2018) Ya-Ling Hsu et al.   MOLECULAR THERAPY

Tumor-derived exosomes antagonize innate antiviral immunity

(2018) Liang Gao et al.   NATURE IMMUNOLOGY

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Metastasis-associated miR-23a from nasopharyngeal carcinoma-derived exosomes mediates angiogenesis by repressing a novel target gene TSGA10

(2018) Lili Bao et al.   ONCOGENE

Exosomal biomarkers in oral diseases

(2018) Mohammad Hadavand et al.   ORAL DISEASES

Oral cancer-derived exosomal NAP1 enhances cytotoxicity of natural killer cells via the IRF-3 pathway

(2018) Yingnan Wang et al.   ORAL ONCOLOGY

Biogenesis and function of extracellular vesicles in cancer

(2018) Maarten P. Bebelman et al.   PHARMACOLOGY & THERAPEUTICS

Hypoxia-Induced Matrix Metalloproteinase-13 Expression in Exosomes from Nasopharyngeal Carcinoma Enhances Metastases

(2018) Ying Shan et al.   Cell Death & Disease

Systematic Methodological Evaluation of a Multiplex Bead-Based Flow Cytometry Assay for Detection of Extracellular Vesicle Surface Signatures

(2018) Oscar P. B. Wiklander et al.   Frontiers in Immunology

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

(2018) Gang Chen et al.   NATURE

Circulating Extracellular Vesicles in Human Disease

(2018) Ravi Shah et al.   NEW ENGLAND JOURNAL OF MEDICINE

Saliva exosomes from pancreatic tumor–bearing mice modulate NK cell phenotype and antitumor cytotoxicity

(2017) Stergios Katsiougiannis et al.   FASEB JOURNAL

Desmoglein 2 modulates extracellular vesicle release from squamous cell carcinoma keratinocytes

(2017) Andrew M. Overmiller et al.   FASEB JOURNAL

Tumor-derived exosomes enhance invasion and metastasis of salivary adenoid cystic carcinoma cells

(2017) Jin Hou et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

miR-200c-3p spreads invasive capacity in human oral squamous cell carcinoma microenvironment

(2017) Tomoyo Kawakubo-Yasukochi et al.   MOLECULAR CARCINOGENESIS

Higher functionality of extracellular vesicles isolated using size-exclusion chromatography compared to ultracentrifugation

(2017) Emma A. Mol et al.   Nanomedicine-Nanotechnology Biology and Medicine

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

(2017) Sushrut Kamerkar et al.   NATURE

Liquid biopsy: An emerging prognostic and predictive tool in Head and Neck Squamous Cell Carcinoma (HNSCC). Focus on Circulating Tumor Cells (CTCs)

(2017) P. Economopoulou et al.   ORAL ONCOLOGY

Cancer acidity: An ultimate frontier of tumor immune escape and a novel target of immunomodulation

(2017) Veronica Huber et al.   SEMINARS IN CANCER BIOLOGY

Systems heterogeneity: An integrative way to understand cancer heterogeneity

(2017) Diane Catherine Wang et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Procoagulant extracellular vesicles in amniotic fluid

(2017) Lena Hell et al.   Translational Research

Human papillomavirus 16 E6 and E7 oncoprotein expression alters microRNA expression in extracellular vesicles

(2017) Mallory E. Harden et al.   VIROLOGY

Exosomes and Other Extracellular Vesicles in HPV Transmission and Carcinogenesis

(2017) David Guenat et al.   Viruses-Basel

Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2

(2017) Masaki Takasugi et al.   Nature Communications

Crosstalk between tongue carcinoma cells, extracellular vesicles, and immune cells in in vitro and in vivo models

(2017) Ahmed Al-Samadi et al.   Oncotarget

Comprehensive microRNA-sequencing of exosomes derived from head and neck carcinoma cells in vitro reveals common secretion profiles and potential utility as salivary biomarkers

(2017) Scott Langevin et al.   Oncotarget

Selective extracellular vesicle exclusion of miR-142-3p by oral cancer cells promotes both internal and extracellular malignant phenotypes

(2017) Christopher T.D. Dickman et al.   Oncotarget

Epiregulin Promotes Lung Metastasis of Salivary Adenoid Cystic Carcinoma

(2017) Wen-Wen Yang et al.   Theranostics

PFKFB3 promotes proliferation, migration and angiogenesis in nasopharyngeal carcinoma

(2017) Miao Gu et al.   Journal of Cancer

Exosomes as diagnostic and predictive biomarkers in lung cancer

(2017) Pablo Reclusa et al.   Journal of Thoracic Disease

Tumor-derived exosomes induce CD8+ T cell suppressors

(2017) Brian T. Maybruck et al.   Journal for ImmunoTherapy of Cancer

Comparative Analysis of MicroRNA Expression among Benign and Malignant Tongue Tissue and Plasma of Patients with Tongue Cancer

(2017) Guilherme Rabinowits et al.   Frontiers in Oncology

Genetic Mutation and Exosome Signature of Human Papilloma Virus Associated Oropharyngeal Cancer

(2017) Anbarasu Kannan et al.   Scientific Reports

Radiation alters the cargo of exosomes released from squamous head and neck cancer cells to promote migration of recipient cells

(2017) Lisa Mutschelknaus et al.   Scientific Reports

Role of extracellular vesicles in autoimmune diseases

(2016) Delphine Turpin et al.   AUTOIMMUNITY REVIEWS

miR-210 and hypoxic microvesicles: Two critical components of hypoxia involved in the regulation of killer cells function

(2016) Muhammad Zaeem Noman et al.   CANCER LETTERS

Exosomes Derived from Hypoxic Oral Squamous Cell Carcinoma Cells Deliver miR-21 to Normoxic Cells to Elicit a Prometastatic Phenotype

(2016) Ling Li et al.   CANCER RESEARCH

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

(2016) Mercedes Tkach et al.   CELL

Cortactin promotes exosome secretion by controlling branched actin dynamics

(2016) Seema Sinha et al.   JOURNAL OF CELL BIOLOGY

Stressors alter intercellular communication and exosome profile of nasopharyngeal carcinoma cells

(2016) Maria Harmati et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Exosomal miR-24-3p impedes T-cell function by targetingFGF11and serves as a potential prognostic biomarker for nasopharyngeal carcinoma

(2016) Shu-Biao Ye et al.   JOURNAL OF PATHOLOGY

CD63 Regulates Epstein-Barr Virus LMP1 Exosomal Packaging, Enhancement of Vesicle Production, and Noncanonical NF-κB Signaling

(2016) Stephanie N. Hurwitz et al.   JOURNAL OF VIROLOGY

Salivary biomarkers in cancer detection

(2016) Xiaoqian Wang et al.   MEDICAL ONCOLOGY

Extracellular vesicles — new tool for joint repair and regeneration

(2016) Jos Malda et al.   Nature Reviews Rheumatology

The development of a liquid biopsy for head and neck cancers

(2016) Henri Schmidt et al.   ORAL ONCOLOGY

Nonlinear association between betel quid chewing and oral cancer: Implications for prevention

(2016) Sreenath Arekunnath Madathil et al.   ORAL ONCOLOGY

Application of a Persistent Heparin Treatment Inhibits the Malignant Potential of Oral Squamous Carcinoma Cells Induced by Tumor Cell-Derived Exosomes

(2016) Shinya Sento et al.   PLoS One

Hypoxic control of metastasis

(2016) E. B. Rankin et al.   SCIENCE

ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins

(2016) Carolina Villarroya-Beltri et al.   Nature Communications

Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1

(2016) Chi Lam Au Yeung et al.   Nature Communications

Exosomes Derived from Squamous Head and Neck Cancer Promote Cell Survival after Ionizing Radiation

(2016) Lisa Mutschelknaus et al.   PLoS One

Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets

(2016) Laurent Muller et al.   Scientific Reports

Exosomal microRNA miR-1246 induces cell motility and invasion through the regulation of DENND2D in oral squamous cell carcinoma

(2016) Sujata Sakha et al.   Scientific Reports

Ionizing radiation affects protein composition of exosomes secreted in vitro from head and neck squamous cell carcinoma

(2015) Karol Jelonek et al.   ACTA BIOCHIMICA POLONICA

Caveolin-1 accumulation in the tongue cancer tumor microenvironment is significantly associated with poor prognosis: an in-vivo and in-vitro study

(2015) Marilena Vered et al.   BMC CANCER

Oral cavity and oropharyngeal squamous cell carcinoma-an update

(2015) Angela C. Chi et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Matrix metalloproteinase 13-containing exosomes promote nasopharyngeal carcinoma metastasis

(2015) Yiwen You et al.   CANCER SCIENCE

The effect of environmental chemicals on the tumor microenvironment

(2015) Stephanie C. Casey et al.   CARCINOGENESIS

Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins

(2015) Yuk-Kit Chan et al.   INTERNATIONAL JOURNAL OF CANCER

Morphological and molecular features of oral fluid-derived exosomes: oral cancer patients versus healthy individuals

(2015) Ayelet Zlotogorski-Hurvitz et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Elevated Level of Circulating Platelet-derived Microparticles in Oral Cancer

(2015) J.G. Ren et al.   JOURNAL OF DENTAL RESEARCH

Metabolic reprogramming: the emerging concept and associated therapeutic strategies

(2015) Go J. Yoshida   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Human salivary proteome — a resource of potential biomarkers for oral cancer

(2015) Priya Sivadasan et al.   Journal of Proteomics

Cancer-associated fibroblasts provide a suitable microenvironment for tumor development and progression in oral tongue squamous cancer

(2015) Huan Li et al.   Journal of Translational Medicine

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

(2015) Lin Zhang et al.   NATURE

Oxidative and other posttranslational modifications in extracellular vesicle biology

(2015) Katalin Szabó-Taylor et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Extracellular vesicles as modulators of the cancer microenvironment

(2015) Jason Webber et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Exosomes and their roles in immune regulation and cancer

(2015) David W. Greening et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation

(2015) Isabel R. Schlaepfer et al.   Oncotarget

Insights into immune responses in oral cancer through proteomic analysis of saliva and salivary extracellular vesicles

(2015) Flavia V. Winck et al.   Scientific Reports

Dependence of Intracellular and Exosomal microRNAs on Viral E6/E7 Oncogene Expression in HPV-positive Tumor Cells

(2015) Anja Honegger et al.   PLoS Pathogens

Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases

(2015) João Henrique Campos et al.   Journal of Immunology Research

Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma

(2015) Shu-biao Ye et al.   Oncotarget

Inflammation-induced endothelial cell-derived extracellular vesicles modulate the cellular status of pericytes

(2015) Seiji Yamamoto et al.   Scientific Reports

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Cellular Disposal of miR23b by RAB27-Dependent Exosome Release Is Linked to Acquisition of Metastatic Properties

(2014) M. S. Ostenfeld et al.   CANCER RESEARCH

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Genomewide Study of Salivary MicroRNAs for Detection of Oral Cancer

(2014) F. Momen-Heravi et al.   JOURNAL OF DENTAL RESEARCH

Exosome Analysis: A Promising Biomarker System with Special Attention to Saliva

(2014) Xiaowen Zheng et al.   JOURNAL OF MEMBRANE BIOLOGY

Effect of Nasopharyngeal Carcinoma-Derived Exosomes on Human Regulatory T Cells

(2014) Dhafer Mrizak et al.   JNCI-Journal of the National Cancer Institute

Combined detection of serum exosomal miR-21 and HOTAIR as diagnostic and prognostic biomarkers for laryngeal squamous cell carcinoma

(2014) Jingting Wang et al.   MEDICAL ONCOLOGY

Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes

(2014) J P Webber et al.   ONCOGENE

Exosomal HIF1α supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes

(2014) M Aga et al.   ONCOGENE

Clinical evidence of field cancerization in patients with oral cavity cancer in a betel quid chewing area

(2014) Chun-Ta Liao et al.   ORAL ONCOLOGY

Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis

(2014) T. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carcinoma-associated fibroblasts provide operational flexibility in metastasis

(2014) Olivier De Wever et al.   SEMINARS IN CANCER BIOLOGY

The Complex Ultrastructure of the Endolysosomal System

(2014) J. Klumperman et al.   Cold Spring Harbor Perspectives in Biology

Immune modulation of T-cell and NK (natural killer) cell activities by TEXs (tumour-derived exosomes)

(2013) Theresa L. Whiteside   BIOCHEMICAL SOCIETY TRANSACTIONS

Pathogenic role of Epstein–Barr virus latent membrane protein-1 in the development of nasopharyngeal carcinoma

(2013) Tomokazu Yoshizaki et al.   CANCER LETTERS

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Worldwide Trends in Incidence Rates for Oral Cavity and Oropharyngeal Cancers

(2013) Anil K. Chaturvedi et al.   JOURNAL OF CLINICAL ONCOLOGY

Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules

(2013) Anand Ramteke et al.   MOLECULAR CARCINOGENESIS

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Hijacking Multivesicular Bodies Enables Long-Term and Exosome-Mediated Long-Distance Action of Anthrax Toxin

(2013) Laurence Abrami et al.   Cell Reports

Oral complications of cancer and cancer therapy

(2012) Joel B. Epstein et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Breast Cancer Exosome-like Microvesicles and Salivary Gland Cells Interplay Alters Salivary Gland Cell-Derived Exosome-like Microvesicles In Vitro

(2012) Chang S. Lau et al.   PLoS One

Molecular crosstalk between cancer cells and tumor microenvironment components suggests potential targets for new therapeutic approaches in mobile tongue cancer

(2012) Dan Dayan et al.   Cancer Medicine

Multivesicular Body Morphogenesis

(2011) Phyllis I. Hanson et al.   Annual Review of Cell and Developmental Biology

Proteomic Analysis of Two Types of Exosomes in Human Whole Saliva

(2011) Yuko Ogawa et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The Tetraspanin CD63 Regulates ESCRT-Independent and -Dependent Endosomal Sorting during Melanogenesis

(2011) Guillaume van Niel et al.   DEVELOPMENTAL CELL

Quantitative Nanostructural and Single-Molecule Force Spectroscopy Biomolecular Analysis of Human-Saliva-Derived Exosomes

(2011) Shivani Sharma et al.   LANGMUIR

A role for caveolin-1 in desmoglein binding and desmosome dynamics

(2011) D Brennan et al.   ONCOGENE

Angiogenesis Inhibitors: Current Strategies and Future Prospects

(2010) K. M. Cook et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cancer Exosomes Trigger Fibroblast to Myofibroblast Differentiation

(2010) J. Webber et al.   CANCER RESEARCH

Nanostructural and Transcriptomic Analyses of Human Saliva Derived Exosomes

(2010) Viswanathan Palanisamy et al.   PLoS One

Human tumor virus utilizes exosomes for intercellular communication

(2010) D. G. Meckes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extra-cellular release and blood diffusion of BART viral micro-RNAs produced by EBV-infected nasopharyngeal carcinoma cells

(2010) Claire Gourzones et al.   Virology Journal

ARF6-Regulated Shedding of Tumor Cell-Derived Plasma Membrane Microvesicles

(2009) Vandhana Muralidharan-Chari et al.   CURRENT BIOLOGY

Tumor-Derived Microvesicles Promote Regulatory T Cell Expansion and Induce Apoptosis in Tumor-Reactive Activated CD8+ T Lymphocytes

(2009) E. U. Wieckowski et al.   JOURNAL OF IMMUNOLOGY

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells

(2008) J. Klibi et al.   BLOOD

Membrane traffic in the secretory pathway

(2008) M. Fukuda   CELLULAR AND MOLECULAR LIFE SCIENCES

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE