Extracellular vesicles — new tool for joint repair and regeneration

Targeting exosomes from preadipocytes inhibits preadipocyte to cancer stem cell signaling in early-stage breast cancer

(2015) Ramkishore Gernapudi et al.   BREAST CANCER RESEARCH AND TREATMENT

In Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior

(2015) Anoek Zomer et al.   CELL

Therapeutic Potential of Multipotent Mesenchymal Stromal Cells and Their Extracellular Vesicles

(2015) Nina Heldring et al.   HUMAN GENE THERAPY

The current state of scaffolds for musculoskeletal regenerative applications

(2015) Benjamin D. Smith et al.   Nature Reviews Rheumatology

Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA

(2015) Anne-Claire Duchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes in bodily fluids are a highly stable resource of disease biomarkers

(2015) Stephanie Boukouris et al.   Proteomics Clinical Applications

Emerging Roles for Extracellular Vesicles in Tissue Engineering and Regenerative Medicine

(2015) Tek N. Lamichhane et al.   TISSUE ENGINEERING PART B-REVIEWS

Host Matrix Modulation by Tumor Exosomes Promotes Motility and Invasiveness

(2015) Wei Mu et al.   NEOPLASIA

Targeting fibroblast-like synovial cells at sites of inflammation with peptide targeted liposomes results in inhibition of experimental arthritis

(2014) A.S. Vanniasinghe et al.   CLINICAL IMMUNOLOGY

TLR4 signalling in osteoarthritis—finding targets for candidate DMOADs

(2014) Rodolfo Gómez et al.   Nature Reviews Rheumatology

Emerging role of extracellular vesicles in inflammatory diseases

(2014) Edit I. Buzas et al.   Nature Reviews Rheumatology

Toll-Like Receptors Expressed by Synovial Fibroblasts Perpetuate Th1 and Th17 Cell Responses in Rheumatoid Arthritis

(2014) Fanlei Hu et al.   PLoS One

Exosomes from IL-1β stimulated synovial fibroblasts induce osteoarthritic changes in articular chondrocytes

(2014) Tomohiro Kato et al.   ARTHRITIS RESEARCH & THERAPY

Mesenchymal Stem Cells in Cartilage Regeneration

(2014) Vuk Savkovic et al.   Current Stem Cell Research & Therapy

Extracellular Vesicle-Mediated Transfer of Genetic Information between the Hematopoietic System and the Brain in Response to Inflammation

(2014) Kirsten Ridder et al.   PLOS BIOLOGY

Concise Review: Unraveling Stem Cell Cocultures in Regenerative Medicine: Which Cell Interactions Steer Cartilage Regeneration and How?

(2014) Tommy S. de Windt et al.   Stem Cells Translational Medicine

Extracellular Vesicle Profiling and Their Use as Potential Disease Specific Biomarker

(2014) Henrike Julich et al.   Frontiers in Immunology

Toll-like receptors in human chondrocytes and osteoarthritic cartilage

(2013) Tarvo Sillat et al.   Acta Orthopaedica

25th Anniversary Article: Engineering Hydrogels for Biofabrication

(2013) Jos Malda et al.   ADVANCED MATERIALS

Exosomes as new vesicular lipid transporters involved in cell–cell communication and various pathophysiologies

(2013) Michel Record et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Body Fluid Exosomes Promote Secretion of Inflammatory Cytokines in Monocytic Cells via Toll-like Receptor Signaling

(2013) Niko P. Bretz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization and deep sequencing analysis of exosomal and non-exosomal miRNA in human urine

(2013) Lesley Cheng et al.   KIDNEY INTERNATIONAL

Overexpression of hsa-miR-148a promotes cartilage production and inhibits cartilage degradation by osteoarthritic chondrocytes

(2013) L.A. Vonk et al.   OSTEOARTHRITIS AND CARTILAGE

Biofabrication of multi-material anatomically shaped tissue constructs

(2013) Jetze Visser et al.   Biofabrication

Articular Cartilage Repair

(2013) Daniel A. Grande et al.   Cartilage

Platelets can enhance vascular permeability

(2012) N. Cloutier et al.   BLOOD

The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes

(2012) Nathalie Cloutier et al.   EMBO Molecular Medicine

The recently identified hexosaminidase D enzyme substantially contributes to the elevated hexosaminidase activity in rheumatoid arthritis

(2012) Mária Pásztói et al.   IMMUNOLOGY LETTERS

Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity

(2012) Alessandra Lo Cicero et al.   MATRIX BIOLOGY

Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

(2012) Shin-ichiro Ohno et al.   MOLECULAR THERAPY

Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells

(2012) Shayne A. Bellingham et al.   NUCLEIC ACIDS RESEARCH

Comparative study of depth-dependent characteristics of equine and human osteochondral tissue from the medial and lateral femoral condyles

(2012) J. Malda et al.   OSTEOARTHRITIS AND CARTILAGE

Improved Flow Cytometric Assessment Reveals Distinct Microvesicle (Cell-Derived Microparticle) Signatures in Joint Diseases

(2012) Bence György et al.   PLoS One

MicroRNAs in Chondrogenesis, Articular Cartilage, and Osteoarthritis: Implications for Tissue Engineering

(2012) Eunmee Hong et al.   TISSUE ENGINEERING PART B-REVIEWS

Mesenchymal stem cell secreted vesicles provide novel opportunities in (stem) cell-free therapy

(2012) Serena Rubina Baglio et al.   Frontiers in Physiology

Role of mesenchymal stem cells in reestablishing immunologic tolerance in autoimmune rheumatic diseases

(2011) Gordon I. A. MacDonald et al.   ARTHRITIS AND RHEUMATISM

The inhibitory effect of microRNA-146a expression on bone destruction in collagen-induced arthritis

(2011) Tomoyuki Nakasa et al.   ARTHRITIS AND RHEUMATISM

The MSC: An Injury Drugstore

(2011) Arnold I. Caplan et al.   Cell Stem Cell

Matrix vesicles are carriers of bone morphogenetic proteins (BMPs), vascular endothelial growth factor (VEGF), and noncollagenous matrix proteins

(2011) Niru N. Nahar et al.   JOURNAL OF BONE AND MINERAL METABOLISM

The Dog as an Animal Model for Intervertebral Disc Degeneration?

(2011) Niklas Bergknut et al.   SPINE

Preclinical Studies for Cartilage Repair

(2011) Mark B. Hurtig et al.   Cartilage

Detection and isolation of cell-derived microparticles are compromised by protein complexes resulting from shared biophysical parameters

(2010) B. Gyorgy et al.   BLOOD

Microparticles stimulate angiogenesis by inducing ELR+ CXC-chemokines in synovial fibroblasts

(2010) Nicole Reich et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Exosomes/microvesicles as a mechanism of cell-to-cell communication

(2010) Giovanni Camussi et al.   KIDNEY INTERNATIONAL

Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production

(2010) E. Boilard et al.   SCIENCE

MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses

(2009) Shigeru Miyaki et al.   ARTHRITIS AND RHEUMATISM

Expression of MicroRNA-146a in osteoarthritis cartilage

(2009) Keiichiro Yamasaki et al.   ARTHRITIS AND RHEUMATISM

Mesenchymal Stem Cell-Derived Microvesicles Protect Against Acute Tubular Injury

(2009) S. Bruno et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Microparticle-induced release of B-lymphocyte regulators by rheumatoid synoviocytes

(2009) Laurent Messer et al.   ARTHRITIS RESEARCH & THERAPY

Cartilage homeostasis in health and rheumatic diseases

(2009) Mary B Goldring et al.   ARTHRITIS RESEARCH & THERAPY

Gene expression and activity of cartilage degrading glycosidases in human rheumatoid arthritis and osteoarthritis synovial fibroblasts

(2009) Mária Pásztói et al.   ARTHRITIS RESEARCH & THERAPY

Phase I Clinical Trial of Autologous Ascites-derived Exosomes Combined With GM-CSF for Colorectal Cancer

(2008) Shengming Dai et al.   MOLECULAR THERAPY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY