Drug delivery systems designed to overcome antimicrobial resistance

Bacteria-Targeting Nanoparticles with Microenvironment-Responsive Antibiotic Release To Eliminate Intracellular Staphylococcus aureus and Associated Infection

(2018) Shengbing Yang et al.   ACS Applied Materials & Interfaces

The challenge of converting Gram-positive-only compounds into broad-spectrum antibiotics

(2018) Michelle F. Richter et al.   Annals of the New York Academy of Sciences

Pharmacokinetics, Safety, and Tolerability of Cefiderocol, a Novel Siderophore Cephalosporin for Gram-Negative Bacteria, in Healthy Subjects

(2018) Yutaka Saisho et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Siderophore–antibiotic conjugates: exploiting iron uptake to deliver drugs into bacteria

(2018) I.J. Schalk   CLINICAL MICROBIOLOGY AND INFECTION

Cefiderocol (S-649266), A new siderophore cephalosporin exhibiting potent activities against Pseudomonas aeruginosa and other gram-negative pathogens including multi-drug resistant bacteria: Structure activity relationship

(2018) Toshiaki Aoki et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pharmacodynamics of cefiderocol, a novel siderophore cephalosporin, in a Pseudomonas aeruginosa neutropenic murine thigh model

(2018) Islam M. Ghazi et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

A Synthetic Dual Drug Sideromycin Induces Gram-Negative Bacteria To Commit Suicide with a Gram-Positive Antibiotic

(2018) Rui Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Trojan-Horse Strategy Including a Bacterial Suicide Action for the Efficient Use of a Specific Gram-Positive Antibiotic on Gram-Negative Bacteria

(2018) Isabelle J. Schalk   JOURNAL OF MEDICINAL CHEMISTRY

Mechanistic insights into staphylopine-mediated metal acquisition

(2018) Liqiang Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antimicrobial polymeric nanoparticles

(2018) Shu J. Lam et al.   PROGRESS IN POLYMER SCIENCE

Recent Advances in the Development of Antimicrobial Nanoparticles for Combating Resistant Pathogens

(2018) Rajamani Lakshminarayanan et al.   Advanced Healthcare Materials

Polymer-augmented liposomes enhancing antibiotic delivery against intracellular infections

(2018) Fang-Yi Su et al.   Biomaterials Science

Antimicrobial Peptides and Their Therapeutic Potential for Bacterial Skin Infections and Wounds

(2018) Anja Pfalzgraff et al.   Frontiers in Pharmacology

Engineering therapeutic antibodies to combat infectious diseases

(2018) Ellen K Wagner et al.   Current Opinion in Chemical Engineering

Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens

(2018) Bradley M. Hover et al.   Nature Microbiology

Application of Nanoparticle Technologies in the Combat against Anti-Microbial Resistance

(2018) et al.   Pharmaceutics

Synergistic Antibacterial Effect of Tetracycline Hydrochloride Loaded Functionalized Graphene Oxide Nanostructures

(2018) Lei Jiang et al.   NANOTECHNOLOGY

Siderophore Conjugates of Daptomycin are Potent Inhibitors of Carbapenem Resistant Strains of Acinetobacter baumannii

(2018) Manuka Ghosh et al.   ACS Infectious Diseases

An enhancement of antimicrobial efficacy of biogenic and ceftriaxone-conjugated silver nanoparticles: green approach

(2017) Rajasree Shanmuganathan et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

An overview of antimicrobial peptides and the latest advances in their development

(2017) Josep M Sierra et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Antimicrobial activities of LCB10-0200, a novel siderophore cephalosporin, against the clinical isolates of Pseudomonas aeruginosa and other pathogens

(2017) Sang-Hun Oh et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Targeted Antibiotic Delivery: Selective Siderophore Conjugation with Daptomycin Confers Potent Activity against Multidrug Resistant Acinetobacter baumannii Both in Vitro and in Vivo

(2017) Manuka Ghosh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antimicrobial peptides as potential anti-biofilm agents against multidrug-resistant bacteria

(2017) Pooi Yin Chung et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Human Antimicrobial Peptides in Bodily Fluids: Current Knowledge and Therapeutic Perspectives in the Postantibiotic Era

(2017) Paulo Bastos et al.   MEDICINAL RESEARCH REVIEWS

Synthesis and Evaluation of Antimicrobial Activity of [R4W4K]-Levofloxacin and [R4W4K]-Levofloxacin-Q Conjugates

(2017) Neda Riahifard et al.   MOLECULES

Nano-therapeutics: A revolution in infection control in post antibiotic era

(2017) Sahar Zaidi et al.   Nanomedicine-Nanotechnology Biology and Medicine

Opportunities for natural products in 21st century antibiotic discovery

(2017) Gerard D. Wright   NATURAL PRODUCT REPORTS

Bifunctional antimicrobial conjugates and hybrid antimicrobials

(2017) P. Klahn et al.   NATURAL PRODUCT REPORTS

Predictive compound accumulation rules yield a broad-spectrum antibiotic

(2017) Michelle F. Richter et al.   NATURE

Antibody–Antibiotic Conjugates: A Novel Therapeutic Platform against Bacterial Infections

(2017) Sanjeev Mariathasan et al.   TRENDS IN MOLECULAR MEDICINE

Cell-Penetrating Peptides: From Basic Research to Clinics

(2017) Giulia Guidotti et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Structural remodeling and oligomerization of human cathelicidin on membranes suggest fibril-like structures as active species

(2017) Enea Sancho-Vaello et al.   Scientific Reports

Mechanisms of envelope permeability and antibiotic influx and efflux in Gram-negative bacteria

(2017) Muriel Masi et al.   Nature Microbiology

Nanomaterials and molecular transporters to overcome the bacterial envelope barrier: Towards advanced delivery of antibiotics

(2017) Rita S. Santos et al.   ADVANCED DRUG DELIVERY REVIEWS

Surface Ligand Density of Antibiotic-Nanoparticle Conjugates Enhances Target Avidity and Membrane Permeabilization of Vancomycin-Resistant Bacteria

(2016) Marwa M. Hassan et al.   BIOCONJUGATE CHEMISTRY

A Gestalt approach to Gram-negative entry

(2016) Lynn L. Silver   BIOORGANIC & MEDICINAL CHEMISTRY

ROSET Model of TonB Action in Gram-Negative Bacterial Iron Acquisition

(2016) Phillip E. Klebba   JOURNAL OF BACTERIOLOGY

The therapeutic applications of antimicrobial peptides (AMPs): a patent review

(2016) Hee-Kyoung Kang et al.   JOURNAL OF MICROBIOLOGY

Alternate “Drug” Delivery Utilizing β-Lactam Cores: Syntheses and Biological Evaluation of β-Lactams Bearing Isocyanate Precursors

(2016) Mark W. Majewski et al.   JOURNAL OF ORGANIC CHEMISTRY

Dual Targeting of Intracellular Pathogenic Bacteria with a Cleavable Conjugate of Kanamycin and an Antibacterial Cell-Penetrating Peptide

(2016) Anna Brezden et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Access to effective antimicrobials: a worldwide challenge

(2016) Ramanan Laxminarayan et al.   LANCET

Understanding the mechanisms and drivers of antimicrobial resistance

(2016) Alison H Holmes et al.   LANCET

Pharmacokinetics and pharmacodynamics of DSTA4637A: A novel THIOMAB™ antibody antibiotic conjugate against Staphylococcus aureus in mice

(2016) Chenguang Zhou et al.   mAbs

In Situ Cultivation Allows for Recovery of Bacterial Types Competitive in Their Natural Environment

(2016) Dawoon Jung et al.   MICROBES AND ENVIRONMENTS

Antibacterial drug discovery in the resistance era

(2016) Eric D. Brown et al.   NATURE

Siderophores in Iron Metabolism: From Mechanism to Therapy Potential

(2016) Briana R. Wilson et al.   TRENDS IN MOLECULAR MEDICINE

Antimicrobial Peptides: An Emerging Category of Therapeutic Agents

(2016) Margit Mahlapuu et al.   Frontiers in Cellular and Infection Microbiology

Potent Antibacterial Nanoparticles against Biofilm and Intracellular Bacteria

(2016) Haibo Mu et al.   Scientific Reports

Mechanisms of biofilm inhibition and degradation by antimicrobial peptides

(2015) L. Segev-Zarko et al.   BIOCHEMICAL JOURNAL

Peptide therapeutics: current status and future directions

(2015) Keld Fosgerau et al.   DRUG DISCOVERY TODAY

The Iron age of host-microbe interactions

(2015) M. P. Soares et al.   EMBO REPORTS

Biofilm-specific antibiotic tolerance and resistance

(2015) I. Olsen   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Macrophage defense mechanisms against intracellular bacteria

(2015) Günter Weiss et al.   IMMUNOLOGICAL REVIEWS

Antimicrobial peptide protegrin-3 adopt an antiparallel dimer in the presence of DPC micelles: a high-resolution NMR study

(2015) K. S. Usachev et al.   JOURNAL OF BIOMOLECULAR NMR

Culture-independent discovery of natural products from soil metagenomes

(2015) Micah Katz et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Diverging roles of bacterial siderophores during infection

(2015) Victoria I. Holden et al.   Metallomics

Bacteria-Targeting Conjugates Based on Antimicrobial Peptide for Bacteria Diagnosis and Therapy

(2015) Haiyan Chen et al.   MOLECULAR PHARMACEUTICS

Pro-Moieties of Antimicrobial Peptide Prodrugs

(2015) Eanna Forde et al.   MOLECULES

Mining the microbial dark matter

(2015) Corie Lok   NATURE

Novel antibody–antibiotic conjugate eliminates intracellular S. aureus

(2015) Sophie M. Lehar et al.   NATURE

A new antibiotic kills pathogens without detectable resistance

(2015) Losee L. Ling et al.   NATURE

ESKAPEing the labyrinth of antibacterial discovery

(2015) Ruben Tommasi et al.   NATURE REVIEWS DRUG DISCOVERY

Salmonellae interactions with host processes

(2015) Doris L. LaRock et al.   NATURE REVIEWS MICROBIOLOGY

APD3: the antimicrobial peptide database as a tool for research and education

(2015) Guangshun Wang et al.   NUCLEIC ACIDS RESEARCH

Evaluation of the antibacterial and antibiofilm activities of novel CRAMP–vancomycin conjugates with diverse linkers

(2015) Nigam M. Mishra et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Targeting intracellular bacteria with an extended cationic amphiphilic polyproline helix

(2015) Manish Nepal et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cell-penetrating peptides: strategies for anticancer treatment

(2015) Drazen Raucher et al.   TRENDS IN MOLECULAR MEDICINE

An efficient system for intracellular delivery of beta-lactam antibiotics to overcome bacterial resistance

(2015) Nadia Abed et al.   Scientific Reports

Discovery of a non-cationic cell penetrating peptide derived from membrane-interacting human proteins and its potential as a protein delivery carrier

(2015) Hyo Young Kim et al.   Scientific Reports

Levofloxacin and Indolicidin for Combination Antimicrobial Therapy

(2015) Khairunnisa Ghaffar et al.   Current Drug Delivery

Peptide Targeting of an Antibiotic Prodrug toward Phagosome-Entrapped Mycobacteria

(2015) Mark P. Pereira et al.   ACS Infectious Diseases

Cell-Penetrating Peptides: Design, Synthesis, and Applications

(2014) Dana Maria Copolovici et al.   ACS Nano

Synthesis and antibacterial activity of catecholate–ciprofloxacin conjugates

(2014) Sylvain Fardeau et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Mining the Metabiome: Identifying Novel Natural Products from Microbial Communities

(2014) Aleksandr Milshteyn et al.   CHEMISTRY & BIOLOGY

Lassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2

(2014) Ekaterina Gavrish et al.   CHEMISTRY & BIOLOGY

Chemistry and Biology of Pyoverdines, Pseudomonas Primary Siderophores

(2014) C. Cezard et al.   CURRENT MEDICINAL CHEMISTRY

Trends and Exceptions of Physical Properties on Antibacterial Activity for Gram-Positive and Gram-Negative Pathogens

(2014) Dean G. Brown et al.   JOURNAL OF MEDICINAL CHEMISTRY

Enterobactin-Mediated Delivery of β-Lactam Antibiotics Enhances Antibacterial Activity against Pathogenic Escherichia coli

(2014) Tengfei Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Antibacterial Activities of Amphiphilic Cyclic Cell-Penetrating Peptides against Multidrug-Resistant Pathogens

(2014) Donghoon Oh et al.   MOLECULAR PHARMACEUTICS

Bacteria, the endoplasmic reticulum and the unfolded protein response: friends or foes?

(2014) Jean Celli et al.   NATURE REVIEWS MICROBIOLOGY

Molecular mechanisms of antibiotic resistance

(2014) Jessica M. A. Blair et al.   NATURE REVIEWS MICROBIOLOGY

AcrB, AcrD, and MdtABC Multidrug Efflux Systems Are Involved in Enterobactin Export in Escherichia coli

(2014) Tsukasa Horiyama et al.   PLoS One

Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7

(2014) Michael Zahn et al.   PROTEIN AND PEPTIDE LETTERS

Molecular mechanisms of antimicrobial tolerance and resistance in bacterial and fungal biofilms

(2014) Heleen Van Acker et al.   TRENDS IN MICROBIOLOGY

Siderophore–drug complexes: potential medicinal applications of the ‘Trojan horse’ strategy

(2014) Agnieszka Górska et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Covalent modification of a ten-residue cationic antimicrobial peptide with levofloxacin

(2014) Carlos A. Rodriguez et al.   Frontiers in Chemistry

Targeting Intracellular Pathogenic Bacteria with Unnatural Proline-Rich Peptides: Coupling Antibacterial Activity with Macrophage Penetration

(2013) Jerrin Kuriakose et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tuning the Intracellular Bacterial Targeting of Peptidic Vectors

(2013) Eric K. Lei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iron in Infection and Immunity

(2013) James E. Cassat et al.   Cell Host & Microbe

Clinical relevance of the ESKAPE pathogens

(2013) Jack N Pendleton et al.   Expert Review of Anti-Infective Therapy

Cell-penetrating peptides: 20 years later, where do we stand?

(2013) Chérine Bechara et al.   FEBS LETTERS

Biscatecholate–Monohydroxamate Mixed Ligand Siderophore–Carbacephalosporin Conjugates are Selective Sideromycin Antibiotics that Target Acinetobacter baumannii

(2013) Timothy A. Wencewicz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evidence for Phenylalanine Zipper-Mediated Dimerization in the X-ray Crystal Structure of a Magainin 2 Analogue

(2013) Zvi Hayouka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Antibiotic resistance—the need for global solutions

(2013) Ramanan Laxminarayan et al.   LANCET INFECTIOUS DISEASES

In SilicoDetermination and Validation of Baumannii Acinetobactin Utilization A Structure and Ligand Binding Site

(2013) Fatemeh Sefid et al.   Biomed Research International

An ABC Transporter with Two Periplasmic Binding Proteins Involved in Iron Acquisition in Pseudomonas aeruginosa

(2012) Karl Brillet et al.   ACS Chemical Biology

Liposomal drug delivery systems: From concept to clinical applications

(2012) Theresa M. Allen et al.   ADVANCED DRUG DELIVERY REVIEWS

Nanoparticles Functionalized with Ampicillin Destroy Multiple-Antibiotic-Resistant Isolates of Pseudomonas aeruginosa and Enterobacter aerogenes and Methicillin-Resistant Staphylococcus aureus

(2012) Ashley N. Brown et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Enhancing membrane disruption by targeting and multivalent presentation of antimicrobial peptides

(2012) Cristina Chamorro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Synthesis and antibacterial activity of conjugates between norfloxacin and analogues of the siderophore vanchrobactin

(2012) Alba Souto et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Cefalexin-immobilized multi-walled carbon nanotubes show strong antimicrobial and anti-adhesion properties

(2012) Xiaobao Qi et al.   CHEMICAL ENGINEERING SCIENCE

Cell-penetrating peptides: classes, origin, and current landscape

(2012) Francesca Milletti   DRUG DISCOVERY TODAY

Exploiting bacterial iron acquisition: siderophore conjugates

(2012) Cheng Ji et al.   Future Medicinal Chemistry

Molecular Determinants of AcrB-Mediated Bacterial Efflux Implications for Drug Discovery

(2012) John I. Manchester et al.   JOURNAL OF MEDICINAL CHEMISTRY

Iron Transport-Mediated Drug Delivery: Practical Syntheses and In Vitro Antibacterial Studies of Tris-Catecholate Siderophore–Aminopenicillin Conjugates Reveals Selectively Potent Antipseudomonal Activity

(2012) Cheng Ji et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Do Cell-Penetrating Peptides Actually “Penetrate” Cellular Membranes?

(2012) Caroline Palm-Apergi et al.   MOLECULAR THERAPY

Enhanced Membrane Pore Formation through High-Affinity Targeted Antimicrobial Peptides

(2012) Christopher J. Arnusch et al.   PLoS One

Role of lipids in the interaction of antimicrobial peptides with membranes

(2012) Vitor Teixeira et al.   PROGRESS IN LIPID RESEARCH

Cell-penetrating peptides: breaking through to the other side

(2012) Erez Koren et al.   TRENDS IN MOLECULAR MEDICINE

β-Lactam-host defence peptide conjugates as antibiotic prodrug candidates targeting resistant bacteria

(2012) Stéphane Desgranges et al.   RSC Advances

Biophysical Mechanisms of Endotoxin Neutralization by Cationic Amphiphilic Peptides

(2011) Yani Kaconis et al.   BIOPHYSICAL JOURNAL

Synthesis and antibacterial activity of amphiphilic lysine-ligated neomycin B conjugates

(2011) Smritilekha Bera et al.   CARBOHYDRATE RESEARCH

Antimicrobial peptides with cell-penetrating peptide properties and vice versa

(2011) Katrin Splith et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Road to clinical efficacy: challenges and novel strategies for antimicrobial peptide development

(2011) Randal Eckert   Future Microbiology

Design, Synthesis, and Study of a Mycobactin−Artemisinin Conjugate That Has Selective and Potent Activity against Tuberculosis and Malaria

(2011) Marvin J. Miller et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Designing antimicrobial peptides: form follows function

(2011) Christopher D. Fjell et al.   NATURE REVIEWS DRUG DISCOVERY

The expanding scope of antimicrobial peptide structures and their modes of action

(2011) Leonard T. Nguyen et al.   TRENDS IN BIOTECHNOLOGY

Antifungal Activity of Amphotericin B Conjugated to Carbon Nanotubes

(2010) Monica Benincasa et al.   ACS Nano

Cationic Amphiphiles, a New Generation of Antimicrobials Inspired by the Natural Antimicrobial Peptide Scaffold

(2010) B. Findlay et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Abolition of Biofilm Formation in Urinary Tract Escherichia coli and Klebsiella Isolates by Metal Interference through Competition for Fur

(2010) V. Hancock et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Use of Ichip for High-Throughput In Situ Cultivation of "Uncultivable" Microbial Species

(2010) D. Nichols et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Antimicrobial and Membrane Disrupting Activities of a Peptide Derived from the Human Cathelicidin Antimicrobial Peptide LL37

(2010) Sathiah Thennarasu et al.   BIOPHYSICAL JOURNAL

Development of Nanoparticles for Antimicrobial Drug Delivery

(2010) L. Zhang et al.   CURRENT MEDICINAL CHEMISTRY

A Straightforward Preparation of Aminoglycoside-Dinucleotide and -diPNA Conjugates via Click Ligation Assisted by Microwaves

(2010) Javier Alguacil et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Specificity of Staphyloferrin B Recognition by the SirA Receptor fromStaphylococcus aureus

(2010) Jason C. Grigg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TheStaphylococcus aureusSiderophore Receptor HtsA Undergoes Localized Conformational Changes to Enclose Staphyloferrin A in an Arginine-rich Binding Pocket

(2010) Jason C. Grigg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemistry and biology of siderophores

(2010) Robert C. Hider et al.   NATURAL PRODUCT REPORTS

How antibiotics kill bacteria: from targets to networks

(2010) Michael A. Kohanski et al.   NATURE REVIEWS MICROBIOLOGY

Siderophores as drug delivery agents: application of the “Trojan Horse” strategy

(2009) Ute Möllmann et al.   BIOMETALS

Arginine-Rich Peptides Destabilize the Plasma Membrane, Consistent with a Pore Formation Translocation Mechanism of Cell-Penetrating Peptides

(2009) H.D. Herce et al.   BIOPHYSICAL JOURNAL

Microbial Iron Acquisition: Marine and Terrestrial Siderophores

(2009) Moriah Sandy et al.   CHEMICAL REVIEWS

Liposomes as delivery systems for antibiotics

(2009) Zuzanna Drulis-Kawa et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The Pseudomonas aeruginosa Pyochelin-Iron Uptake Pathway and Its Metal Specificity

(2009) A. Braud et al.   JOURNAL OF BACTERIOLOGY

Characterization of staphyloferrin A biosynthetic and transport mutants inStaphylococcus aureus

(2009) Federico C. Beasley et al.   MOLECULAR MICROBIOLOGY

Molecular basis of pyoverdine siderophore recycling in Pseudomonas aeruginosa

(2009) F. Imperi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An efflux pump is required for siderophore recycling by Pseudomonas aeruginosa

(2009) Emilie Yeterian et al.   Environmental Microbiology Reports

The Vancomycin−Nisin(1−12) Hybrid Restores Activity against Vancomycin Resistant Enterococci†

(2008) Christopher J. Arnusch et al.   BIOCHEMISTRY

Membrane interaction and perturbation mechanisms induced by two cationic cell penetrating peptides with distinct charge distribution

(2008) I ALVES et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Iron availability and infection

(2008) Eugene D. Weinberg   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Cell-penetrating peptides: from molecular mechanisms to therapeutics

(2008) May C. Morris et al.   BIOLOGY OF THE CELL

Synthesis of glucose-templated lysine analogs and incorporation into the antimicrobial dipeptide sequence kW-OBn

(2008) Kaidong Zhang et al.   CARBOHYDRATE RESEARCH

Cu-Catalyzed Azide−Alkyne Cycloaddition

(2008) Morten Meldal et al.   CHEMICAL REVIEWS

Levofloxacin

(2008) Vanessa R Anderson et al.   DRUGS

Surprising Alteration of Antibacterial Activity of 5′′-Modified Neomycin against Resistant Bacteria

(2008) Jianjun Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Physicochemical Properties of Antibacterial Compounds: Implications for Drug Discovery

(2008) Rosemarie O’Shea et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cell-penetrating peptides as delivery vehicles for biology and medicine

(2008) Kelly M. Stewart et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Eukaryotic expression and antimicrobial spectrum determination of the peptide tachyplesin II

(2008) Feng Xu et al.   PROTEIN EXPRESSION AND PURIFICATION

Rational design of peptides active against the gram positive bacteriaStaphylococcus aureus

(2008) Céline Landon et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Molecular insight into mechanism of antimicrobial action of the β-hairpin peptide arenicin: Specific oligomerization in detergent micelles

(2007) Tatiana V. Ovchinnikova et al.   BIOPOLYMERS

Delivery systems to increase the selectivity of antibiotics in phagocytic cells

(2007) Elsa Briones et al.   JOURNAL OF CONTROLLED RELEASE

Characterization of a Novel Cytotoxic Cell‐penetrating Peptide Derived From p14ARF Protein

(2007) Henrik J Johansson et al.   MOLECULAR THERAPY