An overview of antimicrobial peptides and the latest advances in their development

Enhanced efficacy of imipenem-colistin combination therapy against multiple-drug-resistant Enterobacter cloacae : in vitro activity and a Galleria mellonella model

(2018) Haifei Yang et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Tryptophan-containing lipopeptide antibiotics derived from polymyxin B with activity against Gram positive and Gram negative bacteria

(2016) Ariadna Grau-Campistany et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Interaction between antimicrobial peptides and mycobacteria

(2016) Thomas Gutsmann   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Antifungal peptides: To be or not to be membrane active

(2016) Marina Rautenbach et al.   BIOCHIMIE

Antibiofilm Peptides: Potential as Broad-Spectrum Agents

(2016) Daniel Pletzer et al.   JOURNAL OF BACTERIOLOGY

Dusquetide: A novel innate defense regulator demonstrating a significant and consistent reduction in the duration of oral mucositis in preclinical data and a randomized, placebo-controlled phase 2a clinical study

(2016) Mahesh Kudrimoti et al.   JOURNAL OF BIOTECHNOLOGY

Killing effect of nanoencapsulated colistin sulfate on Pseudomonas aeruginosa from cystic fibrosis patients

(2016) E. Sans-Serramitjana et al.   Journal of Cystic Fibrosis

Alternatives to overcoming bacterial resistances: State-of-the-art

(2016) Alessandra C. Rios et al.   MICROBIOLOGICAL RESEARCH

Synergistic Antipseudomonal Effects of Synthetic Peptide AMP38 and Carbapenems

(2016) Héctor Rudilla et al.   MOLECULES

Risk of drug resistance in Plasmodium falciparum malaria therapy—a systematic review and meta-analysis

(2016) Li-Juan Zhou et al.   PARASITOLOGY RESEARCH

Penicillin-Binding Protein Transpeptidase Signatures for Tracking and Predicting β-Lactam Resistance Levels in Streptococcus pneumoniae

(2016) Yuan Li et al.   mBio

Anti-parasitic Peptides from Arthropods and their Application in Drug Therapy

(2016) Ariane F. Lacerda et al.   Frontiers in Microbiology

Temporizin and Temporizin-1 Peptides as Novel Candidates for Eliminating Trypanosoma cruzi

(2016) André L. A. Souza et al.   PLoS One

Defensive remodeling: How bacterial surface properties and biofilm formation promote resistance to antimicrobial peptides

(2015) Reut Nuri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Membrane interaction of a new synthetic antimicrobial lipopeptide sp-85 with broad spectrum activity

(2015) Ariadna Grau-Campistany et al.   COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS

In vitro synergy of polymyxins with other antibiotics for Acinetobacter baumannii: A systematic review and meta-analysis

(2015) Wentao Ni et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Discovery and development of surotomycin for the treatment of Clostridium difficile

(2015) Victoria Knight-Connoni et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

The Potential Use of Natural and Structural Analogues of Antimicrobial Peptides in the Fight against Neglected Tropical Diseases

(2015) Angélique Lewies et al.   MOLECULES

Precision-guided antimicrobial peptide as a targeted modulator of human microbial ecology

(2015) Lihong Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A bioinspired peptide scaffold with high antibiotic activity and low in vivo toxicity

(2015) Francesc Rabanal et al.   Scientific Reports

Killing of Mycobacterium avium by Lactoferricin Peptides: Improved Activity of Arginine- and d-Amino-Acid-Containing Molecules

(2014) Tânia Silva et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Antibacterial Screening of Six Proline-Based Cyclic Dipeptides in Combination with β-Lactam Antibiotics Against Medically Important Bacteria

(2014) S. Nishanth Kumar et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Sodium colistimethate loaded lipid nanocarriers for the treatment of Pseudomonas aeruginosa infections associated with cystic fibrosis

(2014) Marta Pastor et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In Vitro Synergistic Activity of Colistin and Ceftazidime or Ciprofloxacin Against Multidrug-Resistant Clinical Strains of Pseudomonas aeruginosa

(2014) Beena Benita D'Souza et al.   Microbial Drug Resistance

In vitro activity and in vivo animal model efficacy of IB-367 alone and in combination with imipenem and colistin against Gram-negative bacteria

(2014) Oriana Simonetti et al.   PEPTIDES

Colistin and anti-Gram-positive bacterial agents against Acinetobacter baumannii

(2014) Bin Liu et al.   Revista da Sociedade Brasileira de Medicina Tropical

Cationic amphipathic D-enantiomeric antimicrobial peptides with in vitro and ex vivo activity against drug-resistant Mycobacterium tuberculosis

(2014) Yun Lan et al.   TUBERCULOSIS

Antimicrobial peptides and proteins in mycobacterial therapy: Current status and future prospects

(2014) Avinash Padhi et al.   TUBERCULOSIS

Synergistic interaction of PMAP-36 and PRW4 with aminoglycoside antibiotics and their antibacterial mechanism

(2014) Zeyun Wang et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Combined Systems Approaches Reveal Highly Plastic Responses to Antimicrobial Peptide Challenge in Escherichia coli

(2014) Justyna Kozlowska et al.   PLoS Pathogens

Targeting Mycobacterium tuberculosis and Other Microbial Pathogens Using Improved Synthetic Antibacterial Peptides

(2013) Santiago Ramón-García et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

10 x '20 Progress--Development of New Drugs Active Against Gram-Negative Bacilli: An Update From the Infectious Diseases Society of America

(2013) H. W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

A Current Perspective on Daptomycin for the Clinical Microbiologist

(2013) R. M. Humphries et al.   CLINICAL MICROBIOLOGY REVIEWS

Synergy of imipenem/colistin methanesulfonate combinations against imipenem-nonsusceptible multidrug-resistant Acinetobacter baumannii

(2013) Hsieh-Shong Leu et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Cathelicidin-like Helminth Defence Molecules (HDMs): Absence of Cytotoxic, Anti-microbial and Anti-protozoan Activities Imply a Specific Adaptation to Immune Modulation

(2013) Karine Thivierge et al.   PLoS Neglected Tropical Diseases

Antimicrobial Peptide Action on Parasites

(2012) Marc Torrent et al.   CURRENT DRUG TARGETS

Therapeutic Potential of Host Defense Peptides in Antibiotic-resistant Infections

(2012) Nicole J. Afacan et al.   CURRENT PHARMACEUTICAL DESIGN

Resistance to antimicrobial peptides in Gram-negative bacteria

(2012) Samantha Gruenheid et al.   FEMS MICROBIOLOGY LETTERS

Activity of LL-37, CRAMP and antimicrobial peptide-derived compounds E2, E6 and CP26 against Mycobacterium tuberculosis

(2012) Bruno Rivas-Santiago et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Natural antimicrobial peptides from bacteria: characteristics and potential applications to fight against antibiotic resistance

(2012) M. Hassan et al.   JOURNAL OF APPLIED MICROBIOLOGY

Role of lipids in the interaction of antimicrobial peptides with membranes

(2012) Vitor Teixeira et al.   PROGRESS IN LIPID RESEARCH

In VivoEfficacy of Glycopeptide-Colistin Combination Therapies in aGalleria mellonellaModel ofAcinetobacter baumanniiInfection

(2011) M. Hornsey et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial peptide killing of African trypanosomes

(2011) J. M. HARRINGTON   PARASITE IMMUNOLOGY

The expanding scope of antimicrobial peptide structures and their modes of action

(2011) Leonard T. Nguyen et al.   TRENDS IN BIOTECHNOLOGY

Novel short antibacterial and antifungal peptides with low cytotoxicity: Efficacy and action mechanisms

(2010) Xiaobao Qi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antibiotic resistance of bacterial biofilms

(2010) Niels Høiby et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Origins and Evolution of Antibiotic Resistance

(2010) J. Davies et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa

(2010) N. Srinivas et al.   SCIENCE

Advances in Peptide Pharmaceuticals

(2009) Cynthia Stevenson   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Amphibian antimicrobial peptides and Protozoa: Lessons from parasites

(2008) Luis Rivas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Antimicrobial peptides (Temporin A and Iseganan IB-367): Effect on the cysticerci of Taenia crassiceps

(2008) Abraham Landa et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY