Enhancer of zeste homolog 2 (EZH2) regulates adipocyte lipid metabolism independent of adipogenic differentiation: Role of apolipoprotein E

Deletion of the Duffy antigen receptor for chemokines (DARC) promotes insulin resistance and adipose tissue inflammation during high fat feeding

(2018) Tyler W. Benson et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A novel role for the Wnt inhibitor APCDD1 in adipocyte differentiation: Implications for diet-induced obesity

(2017) Nicole K. H. Yiew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of EZH2 in aerobic glycolysis of prostate cancer through miR-181b/HK2 axis

(2017) Tao Tao et al.   ONCOLOGY REPORTS

Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas

(2016) Rishi G. Vaswani et al.   JOURNAL OF MEDICINAL CHEMISTRY

Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is Not Required for Brown Adipogenesis but Regulates Brown Adipose Tissue Development and Function

(2016) Hongyi Zhou et al.   MOLECULAR AND CELLULAR BIOLOGY

S6K1 Phosphorylation of H2B Mediates EZH2 Trimethylation of H3: A Determinant of Early Adipogenesis

(2016) Sang Ah Yi et al.   MOLECULAR CELL

Suppression of EZH2 Prevents the Shift of Osteoporotic MSC Fate to Adipocyte and Enhances Bone Formation During Osteoporosis

(2016) Huan Jing et al.   MOLECULAR THERAPY

Enhancer of Zeste Homolog 2 and Histone Deacetylase 9c Regulate Age-Dependent Mesenchymal Stem Cell Differentiation into Osteoblasts and Adipocytes

(2016) Ya-Huey Chen et al.   STEM CELLS

Disruption of the EZH2/miRNA/β-catenin signaling suppresses aerobic glycolysis in glioma

(2016) Yingyi Wang et al.   Oncotarget

EZH2 promotes metabolic reprogramming in glioblastomas through epigenetic repression of EAF2-HIF1α signaling

(2016) Bo Pang et al.   Oncotarget

Transition of differential histone H3 methylation in photoreceptors and other retinal cells during retinal differentiation

(2016) Kazuko Ueno et al.   Scientific Reports

Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2

(2015) Amel Dudakovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective suppression of adipose tissue apoE expression impacts systemic metabolic phenotype and adipose tissue inflammation

(2014) Zhi H. Huang et al.   JOURNAL OF LIPID RESEARCH

Selective Inhibition of EZH2 by EPZ-6438 Leads to Potent Antitumor Activity in EZH2-Mutant Non-Hodgkin Lymphoma

(2014) S. K. Knutson et al.   MOLECULAR CANCER THERAPEUTICS

EZH2: biology, disease and structure-based drug discovery

(2013) Jin-zhi Tan et al.   ACTA PHARMACOLOGICA SINICA

EZH2 Down-Regulation Exacerbates Lipid Accumulation and Inflammation in in Vitro and in Vivo NAFLD

(2013) Serena Vella et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Adiponectin is expressed and secreted by renal tubular epithelial cells

(2013) Anna Perri et al.   JOURNAL OF NEPHROLOGY

Targeted disruption of the EZH2–EED complex inhibits EZH2-dependent cancer

(2013) Woojin Kim et al.   Nature Chemical Biology

EZH2andKDM6AAct as an Epigenetic Switch to Regulate Mesenchymal Stem Cell Lineage Specification

(2013) Sarah Hemming et al.   STEM CELLS

Genome-wide analysis identifies a functional association of Tet1 and Polycomb repressive complex 2 in mouse embryonic stem cells

(2013) Francesco Neri et al.   GENOME BIOLOGY

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

ApoE and the role of very low density lipoproteins in adipose tissue inflammation

(2012) Jiali Wang et al.   ATHEROSCLEROSIS

Apolipoprotein E2 Accentuates Postprandial Inflammation and Diet-Induced Obesity to Promote Hyperinsulinemia in Mice

(2012) D. G. Kuhel et al.   DIABETES

Adiposoft: automated software for the analysis of white adipose tissue cellularity in histological sections

(2012) Miguel Galarraga et al.   JOURNAL OF LIPID RESEARCH

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

(2012) Michael T. McCabe et al.   NATURE

Histone Deacetylase 9 Is a Negative Regulator of Adipogenic Differentiation

(2011) Tapan K. Chatterjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S-adenosylhomocysteine hydrolase inhibition by 3-deazaneplanocin A analogues induces anti-cancer effects in breast cancer cell lines and synergy with both histone deacetylase and HER2 inhibition

(2010) Annette Hayden et al.   BREAST CANCER RESEARCH AND TREATMENT

Rates of lipid fluxes in adipose tissue in vivo after a mixed meal in morbid obesity

(2010) P Mitrou et al.   INTERNATIONAL JOURNAL OF OBESITY

Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis

(2010) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism for Endogenously Expressed ApoE Modulation of Adipocyte Very Low Density Lipoprotein Metabolism

(2009) Zhi Hua Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EZH1 Mediates Methylation on Histone H3 Lysine 27 and Complements EZH2 in Maintaining Stem Cell Identity and Executing Pluripotency

(2008) Xiaohua Shen et al.   MOLECULAR CELL