EZH2 Down-Regulation Exacerbates Lipid Accumulation and Inflammation in in Vitro and in Vivo NAFLD

Influence of Metabolism on Epigenetics and Disease

(2013) William G. Kaelin et al.   CELL

Epidemiology and Natural History of Patients with NAFLD

(2013) Neeraj Bhala et al.   CURRENT PHARMACEUTICAL DESIGN

Genomic aspects of NAFLD pathogenesis

(2013) Adviti Naik et al.   GENOMICS

Dual Role of MicroRNAs in NAFLD

(2013) Sara Ceccarelli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NAFLD in Asia—as common and important as in the West

(2013) Geoffrey C. Farrell et al.   Nature Reviews Gastroenterology & Hepatology

Regulation of nucleosome dynamics by histone modifications

(2013) Gabriel E Zentner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA methylation dynamics in health and disease

(2013) Yehudit Bergman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Why Are Genetics Important for Nutrition? Lessons from Epigenetic Research

(2012) Frank M. Ruemmele et al.   ANNALS OF NUTRITION AND METABOLISM

A Myriad of Pathways to NASH

(2012) Soledad Larrain et al.   Clinics in Liver Disease

DNA methylation and hepatic insulin resistance and steatosis

(2012) Silvia Sookoian et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Enhancer of zeste homologue 2 (EZH2) is a reliable immunohistochemical marker to differentiate malignant and benign hepatic tumors

(2012) Szofia Hajósi-Kalcakosz et al.   Diagnostic Pathology

Mallory–Denk bodies form when EZH2/H3K27me3 fails to methylate DNA in the nuclei of human and mice liver cells

(2012) B.A. French et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Epigenetic modification of liver mitochondrial DNA is associated with histological severity of nonalcoholic fatty liver disease

(2012) Carlos Jose Pirola et al.   GUT

Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis

(2012) Sandy Leung-Kuen Au et al.   HEPATOLOGY

Non-coding RNAs and EZH2 interactions in cancer: Long and short tales from the transcriptome

(2012) Leonidas Benetatos et al.   INTERNATIONAL JOURNAL OF CANCER

Emodin Prevents Intrahepatic Fat Accumulation, Inflammation and Redox Status Imbalance During Diet-Induced Hepatosteatosis in Rats

(2012) Anna Alisi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A 360-degree overview of paediatric NAFLD: Recent insights

(2012) Valerio Nobili et al.   JOURNAL OF HEPATOLOGY

Molecular architecture of human polycomb repressive complex 2

(2012) Claudio Ciferri et al.   eLife

Genetics and epigenetics in the fibrogenic evolution of chronic liver diseases

(2011) Vincent Zimmer et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications

(2011) Roberta Ciarapica et al.   BMC Medicine

Deregulated expression of miR-26a and Ezh2 in Rhabdomyosarcoma

(2011) Roberta Ciarapica et al.   CELL CYCLE

MicroRNAs and epigenetics

(2011) Fumiaki Sato et al.   FEBS Journal

EZH2 protein: a promising immunomarker for the detection of hepatocellular carcinomas in liver needle biopsies

(2011) M.-Y. Cai et al.   GUT

S-adenosylhomocysteine hydrolase inhibition by 3-deazaneplanocin A analogues induces anti-cancer effects in breast cancer cell lines and synergy with both histone deacetylase and HER2 inhibition

(2010) Annette Hayden et al.   BREAST CANCER RESEARCH AND TREATMENT

Nonalcoholic Fatty Liver Disease

(2010) Kathryn Law et al.   Clinics in Liver Disease

The Role of Cytokines in Non-Alcoholic Fatty Liver Disease

(2010) Herbert Tilg   DIGESTIVE DISEASES

Epigenetic regulation of insulin resistance in nonalcoholic fatty liver disease: Impact of liver methylation of the peroxisome proliferator-activated receptor γ coactivator 1α promoter

(2010) Silvia Sookoian et al.   HEPATOLOGY

Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155 and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice

(2010) Igor P Pogribny et al.   LABORATORY INVESTIGATION

Mirnome analysis reveals novel molecular determinants in the pathogenesis of diet-induced nonalcoholic fatty liver disease

(2010) Anna Alisi et al.   LABORATORY INVESTIGATION

Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells

(2009) W. Fiskus et al.   BLOOD

Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet

(2009) Igor P. Pogribny et al.   JOURNAL OF HEPATOLOGY

Targeting Id protein interactions by an engineered HLH domain induces human neuroblastoma cell differentiation

(2009) R Ciarapica et al.   ONCOGENE

Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

(2008) S. Varambally et al.   SCIENCE