Targeting Protein Kinases to Enhance the Response to anti-PD-1/PD-L1 Immunotherapy
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting Protein Kinases to Enhance the Response to anti-PD-1/PD-L1 Immunotherapy
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 9, Pages 2296
Publisher
MDPI AG
Online
2019-05-09
DOI
10.3390/ijms20092296
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Targeting Receptor Kinases in Colorectal Cancer
- (2019) Marilina García-Aranda et al. Cancers
- Osimertinib Plus Durvalumab versus Osimertinib Monotherapy in EGFR T790M–Positive NSCLC following Previous EGFR TKI Therapy: CAURAL Brief Report
- (2019) James Chih-Hsin Yang et al. Journal of Thoracic Oncology
- Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non–small cell lung cancer
- (2019) Bo Gong et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Sequential therapy with ramucirumab and/or checkpoint inhibitors for non-small-cell lung cancer in routine practice
- (2019) Cliff Molife et al. Future Oncology
- Dying to communicate: apoptotic functions of Eph/Ephrin proteins
- (2018) Mustapha Kandouz APOPTOSIS
- Mechanisms of Resistance to PD-1 and PD-L1 Blockade
- (2018) Theodore S. Nowicki et al. CANCER JOURNAL
- Future applications of FGF/FGFR inhibitors in cancer
- (2018) Gaia Cristina Ghedini et al. Expert Review of Anticancer Therapy
- Regulation and Function of the PD-L1 Checkpoint
- (2018) Chong Sun et al. IMMUNITY
- Inhibitors of the PD-1 Pathway in Tumor Therapy
- (2018) Martin W. LaFleur et al. JOURNAL OF IMMUNOLOGY
- Nivolumab Plus Erlotinib in Patients With EGFR -Mutant Advanced NSCLC
- (2018) Scott Gettinger et al. Journal of Thoracic Oncology
- Effect of mutant variants of the KRAS gene on PD-L1 expression and on the immune microenvironment and association with clinical outcome in lung adenocarcinoma patients
- (2018) Alexander T. Falk et al. LUNG CANCER
- Kinase-targeted cancer therapies: progress, challenges and future directions
- (2018) Khushwant S. Bhullar et al. Molecular Cancer
- mTOR at the Transmitting and Receiving Ends in Tumor Immunity
- (2018) Yakir Guri et al. Frontiers in Immunology
- Targeting VEGF/VEGFR to Modulate Antitumor Immunity
- (2018) Ju Yang et al. Frontiers in Immunology
- Clinical and Molecular Characteristics Associated With Survival Among Patients Treated With Checkpoint Inhibitors for Advanced Non–Small Cell Lung Carcinoma
- (2018) Chee Khoon Lee et al. JAMA Oncology
- Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations
- (2018) Judith A. Seidel et al. Frontiers in Oncology
- Somatic STK11/LKB1 mutations to confer resistance to immune checkpoint inhibitors as monotherapy or in combination in advanced NSCLC.
- (2018) Maria Jure-Kunkel et al. JOURNAL OF CLINICAL ONCOLOGY
- Molecular characterization of cancers with NTRK gene fusions
- (2018) Zoran Gatalica et al. MODERN PATHOLOGY
- Biomarkers for predicting efficacy of PD-1/PD-L1 inhibitors
- (2018) Ming Yi et al. Molecular Cancer
- Signaling by Discoidin Domain Receptor 1 in Cancer Metastasis
- (2018) Mayur Gadiya et al. Cell Adhesion & Migration
- Single-cell transcriptomes reveal the mechanism for a breast cancer prognostic gene panel
- (2018) Shengwen Calvin Li et al. Oncotarget
- Targeting IKKβ in Cancer: Challenges and Opportunities for the Therapeutic Utilisation of IKKβ Inhibitors
- (2018) Jack Prescott et al. Cells
- LBA6_PRJAVELIN renal 101: A randomized, phase III study of avelumab + axitinib vs sunitinib as first-line treatment of advanced renal cell carcinoma (aRCC)
- (2018) R J Motzer et al. ANNALS OF ONCOLOGY
- Long-Term Survival in Patients Responding to Anti–PD-1/PD-L1 Therapy and Disease Outcome upon Treatment Discontinuation
- (2018) Marie-Léa Gauci et al. CLINICAL CANCER RESEARCH
- Cemiplimab: First Global Approval
- (2018) Anthony Markham et al. DRUGS
- Bcl-2 Inhibition to Overcome Resistance to Chemo- and Immunotherapy
- (2018) Marilina García-Aranda et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- NTRK fusion-positive cancers and TRK inhibitor therapy
- (2018) Emiliano Cocco et al. Nature Reviews Clinical Oncology
- RARE-08. GRADING CONSIDERATIONS FOR MENINGEAL SOLITARY FIBROUS TUMOR/HEMANGIOPERICYTOMA
- (2018) Karen Fritchie et al. NEURO-ONCOLOGY
- Predictive biomarkers for tumor immune checkpoint blockade
- (2018) Mengting Tong et al. Cancer Management and Research
- Safety and efficacy of nivolumab in combination with sunitinib or pazopanib in advanced or metastatic renal cell carcinoma: the CheckMate 016 study
- (2018) Asim Amin et al. Journal for ImmunoTherapy of Cancer
- Cancer immunotherapy: Opportunities and challenges in the rapidly evolving clinical landscape
- (2017) Leisha A. Emens et al. EUROPEAN JOURNAL OF CANCER
- Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma
- (2017) Suzanne George et al. IMMUNITY
- Protein Kinase Targets in Breast Cancer
- (2017) Marilina García-Aranda et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- P2.07-003 Nivolumab for Patients with EGFR Mutation-Positive Non-Small Cell Lung Cancer
- (2017) H. Yoshida et al. Journal of Thoracic Oncology
- The regulatory network behind MHC class I expression
- (2017) Marlieke L.M. Jongsma et al. MOLECULAR IMMUNOLOGY
- Emerging functions of the EGFR in cancer
- (2017) Sara Sigismund et al. Molecular Oncology
- Function of insulin‑like growth factor 1 receptor in cancer resistance to chemotherapy (Review)
- (2017) Jingsheng Yuan et al. Oncology Letters
- mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation
- (2017) Victor H. Villar et al. Nature Communications
- Regulation of PD-1/PD-L1 pathway and resistance to PD-1/PDL1 blockade
- (2017) Jie Bai et al. Oncotarget
- PD1 signal transduction pathways in T cells
- (2017) Hugo Arasanz et al. Oncotarget
- Soluble PD-1 and PD-L1: predictive and prognostic significance in cancer
- (2017) Xinxin Zhu et al. Oncotarget
- IL-17 induces reactive astrocytes and up-regulation of vascular endothelial growth factor (VEGF) through JAK/STAT signaling
- (2017) Tao You et al. Scientific Reports
- AKT in cancer: new molecular insights and advances in drug development
- (2016) Prabhjot S. Mundi et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Prognostic relevance of genetic variants involved in immune checkpoints in patients with colorectal cancer
- (2016) Shinkyo Yoon et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Genetic and Epigenetic Regulation of PD-1 Expression
- (2016) Alexander P. R. Bally et al. JOURNAL OF IMMUNOLOGY
- mTORC1 and mTORC2 in cancer and the tumor microenvironment
- (2016) L C Kim et al. ONCOGENE
- The Tumor Microenvironment Mediates GBM Resistance to CSF1R Blockade
- (2016) Cancer Discovery
- Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells
- (2016) Maryam Abbaspour Babaei et al. Drug Design Development and Therapy
- Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells
- (2016) Won-Sik Shin et al. Oncotarget
- Discoidin domain receptor 1 promotes Th17 cell migration by activating the RhoA/ROCK/MAPK/ERK signaling pathway
- (2016) Mohammed-Amine El Azreq et al. Oncotarget
- Kinase Regulation of Human MHC Class I Molecule Expression on Cancer Cells
- (2016) E. J. Brea et al. Cancer Immunology Research
- The PD1:PD-L1/2 Pathway from Discovery to Clinical Implementation
- (2016) Kankana Bardhan et al. Frontiers in Immunology
- Serine threonine tyrosine kinase 1 is a potential prognostic marker in colorectal cancer
- (2015) Liang Hu et al. BMC CANCER
- Platelet-derived growth factor (PDGF) signalling in cancer: rapidly emerging signalling landscape
- (2015) Ammad Ahmad Farooqi et al. CELL BIOCHEMISTRY AND FUNCTION
- RAS-MAPK in ALK targeted therapy resistance
- (2015) Gorjan Hrustanovic et al. CELL CYCLE
- The FGFR Landscape in Cancer: Analysis of 4,853 Tumors by Next-Generation Sequencing
- (2015) T. Helsten et al. CLINICAL CANCER RESEARCH
- Protein kinase Cδ regulates nuclear export of FOXO1 through phosphorylation of the chaperone 14-3-3ζ
- (2015) Felicia Gerst et al. DIABETOLOGIA
- Novel Roles of c-Met in the Survival of Renal Cancer Cells through the Regulation of HO-1 and PD-L1 Expression
- (2015) Murugabaskar Balan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Novel Dual Kinase Function of the RET Proto-oncogene Negatively Regulates Activating Transcription Factor 4-mediated Apoptosis
- (2015) Rozita Bagheri-Yarmand et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting cancer with kinase inhibitors
- (2015) Stefan Gross et al. JOURNAL OF CLINICAL INVESTIGATION
- Antagonists of PD-1 and PD-L1 in Cancer Treatment
- (2015) Evan J. Lipson et al. SEMINARS IN ONCOLOGY
- The Role of the Insulin/IGF System in Cancer: Lessons Learned from Clinical Trials and the Energy Balance-Cancer Link
- (2015) Laura W. Bowers et al. Frontiers in Endocrinology
- Silencing of Receptor Tyrosine Kinase ROR1 Inhibits Tumor-Cell Proliferation via PI3K/AKT/mTOR Signaling Pathway in Lung Adenocarcinoma
- (2015) Yanchun Liu et al. PLoS One
- Targeting lemurs against cancer metastasis
- (2015) Oncotarget
- Protein-tyrosine Pseudokinase 7 (PTK7) Directs Cancer Cell Motility and Metastasis
- (2014) Vladislav S. Golubkov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NFATc1 Regulates PD-1 Expression upon T Cell Activation
- (2014) K. J. Oestreich et al. JOURNAL OF IMMUNOLOGY
- PTEN function: the long and the short of it
- (2014) Benjamin D. Hopkins et al. TRENDS IN BIOCHEMICAL SCIENCES
- JNK signalling in cancer: in need of new, smarter therapeutic targets
- (2013) Concetta Bubici et al. BRITISH JOURNAL OF PHARMACOLOGY
- Serum lemur tyrosine kinase 3 expression in colorectal cancer patients predicts cancer progression and prognosis
- (2013) Hongbing Shi et al. MEDICAL ONCOLOGY
- FGF Receptors: Cancer Biology and Therapeutics
- (2013) Masaru Katoh et al. MEDICINAL RESEARCH REVIEWS
- The VEGF Pathway in Cancer and Disease: Responses, Resistance, and the Path Forward
- (2013) M. W. Kieran et al. Cold Spring Harbor Perspectives in Medicine
- Two signal models in innate immunity
- (2011) Mary F. Fontana et al. IMMUNOLOGICAL REVIEWS
- Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex
- (2011) S. Sharma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression Regulation of Major Histocompatibility Complex Class I and Class II Encoding Genes
- (2011) Peter J. van den Elsen Frontiers in Immunology
- TAM receptors and the clearance of apoptotic cells
- (2010) Greg Lemke et al. Annals of the New York Academy of Sciences
- Eph/ephrin molecules--a hub for signaling and endocytosis
- (2010) M. E. Pitulescu et al. GENES & DEVELOPMENT
- ROS receptor tyrosine kinase: a new potential target for anticancer drugs
- (2010) Ibrahim Mustafa El-Deeb et al. MEDICINAL RESEARCH REVIEWS
- Treatment combinations targeting apoptosis to improve immunotherapy of melanoma
- (2009) Peter Hersey et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Signal Transducers and Activators of Transcription Mediate Fibroblast Growth Factor–Induced Vascular Endothelial Morphogenesis
- (2009) Xinhai Yang et al. CANCER RESEARCH
- The NF- B Family of Transcription Factors and Its Regulation
- (2009) A. Oeckinghaus et al. Cold Spring Harbor Perspectives in Biology
- Tumor resistance to apoptosis
- (2008) Simone Fulda INTERNATIONAL JOURNAL OF CANCER
- ExplorEnz: the primary source of the IUBMB enzyme list
- (2008) A. G. McDonald et al. NUCLEIC ACIDS RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started