Protein kinase Cδ regulates nuclear export of FOXO1 through phosphorylation of the chaperone 14-3-3ζ

Legacy Effect of Foxo1 in Pancreatic Endocrine Progenitors on Adult β-Cell Mass and Function

(2015) Shivatra Chutima Talchai et al.   DIABETES

Metabolic Inflexibility Impairs Insulin Secretion and Results In MODY-like Diabetes in Triple FoxO-Deficient Mice

(2014) Ja Young Kim-Muller et al.   Cell Metabolism

BH3-Only Molecule Bim Mediates  -Cell Death in IRS2 Deficiency

(2014) D. Ren et al.   DIABETES

AMP-activated protein kinase mediates the antioxidant effects of resveratrol through regulation of the transcription factor FoxO1

(2014) Hee Yun et al.   FEBS Journal

Minireview: Thioredoxin-Interacting Protein: Regulation and Function in the Pancreatic β-Cell

(2014) Anath Shalev   MOLECULAR ENDOCRINOLOGY

14-3-3 proteins are essential signalling hubs for beta cell survival

(2013) G. E. Lim et al.   DIABETOLOGIA

Regulation of forkhead box O1 (FOXO1) by protein kinase B and glucocorticoids: different mechanisms of induction of beta cell death in vitro

(2013) G. Kaiser et al.   DIABETOLOGIA

PKCδ is activated in the liver of obese Zucker rats and mediates diet-induced whole body insulin resistance and hepatocyte cellular insulin resistance

(2013) Michael W. Greene et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

FOXOs: signalling integrators for homeostasis maintenance

(2013) Astrid Eijkelenboom et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FoxO1 as a double-edged sword in the pancreas: analysis of pancreas- and β-cell-specific FoxO1 knockout mice

(2012) Masaki Kobayashi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription

(2011) Emilyn U. Alejandro et al.   FASEB JOURNAL

PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans

(2011) Olivier Bezy et al.   JOURNAL OF CLINICAL INVESTIGATION

Two Faces of Protein Kinase Cδ: The Contrasting Roles of PKCδ in Cell Survival and Cell Death

(2011) Alakananda Basu et al.   TheScientificWorldJOURNAL

Deletion of protein kinase Cδ in mice modulates stability of inflammatory genes and protects against cytokine-stimulated beta cell death in vitro and in vivo

(2010) J. Cantley et al.   DIABETOLOGIA

Protein kinase Cdelta is associated with 14-3-3 phosphorylation in seizure-induced neuronal death

(2010) Yoon Sook Kim et al.   EPILEPSY RESEARCH

Uncoupling of Acetylation from Phosphorylation Regulates FoxO1 Function Independent of Its Subcellular Localization

(2010) Li Qiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FoxO1 induces apoptosis in skeletal myotubes in a DNA-binding-dependent manner

(2009) Thomas J. McLoughlin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Overexpression of Kinase-Negative Protein Kinase C  in Pancreatic  -Cells Protects Mice From Diet-Induced Glucose Intolerance and  -Cell Dysfunction

(2009) A. M. Hennige et al.   DIABETES

Association of Common Genetic Variation in theFOXO1Gene with β-Cell Dysfunction, Impaired Glucose Tolerance, and Type 2 Diabetes

(2009) Karsten Müssig et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Serum- and Glucocorticoid-Inducible Kinase 1 (SGK1) Regulates Adipocyte Differentiation via Forkhead Box O1

(2009) Natalia Di Pietro et al.   MOLECULAR ENDOCRINOLOGY

Islet Inflammation Impairs the Pancreatic β-Cell in Type 2 Diabetes

(2009) Marc Y. Donath et al.   PHYSIOLOGY

Inhibition of Foxo1 Protects Pancreatic Islet  -Cells Against Fatty Acid and Endoplasmic Reticulum Stress-Induced Apoptosis

(2008) S. C. Martinez et al.   DIABETES

Thioredoxin-Interacting Protein: A Critical Link Between Glucose Toxicity and  -Cell Apoptosis

(2008) J. Chen et al.   DIABETES

PP2A Regulates the Pro-apoptotic Activity of FOXO1

(2008) Ling Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Initiation and execution of lipotoxic ER stress in pancreatic  -cells

(2008) D. A. Cunha et al.   JOURNAL OF CELL SCIENCE

PKC δ in Preeclamptic Placentas Promotes Bax Dissociation from 14-3-3 ζ through 14-3-3 ζ Phosphorylation

(2008) J.K. Park et al.   PLACENTA