Pharmacomicrobiomics: The Holy Grail to Variability in Drug Response?

Mechanistic and structural insight into promiscuity based metabolism of cardiac drug digoxin by gut microbial enzyme

(2018) Kundan Kumar et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

From correlation to causation: analysis of metabolomics data using systems biology approaches

(2018) Antonio Rosato et al.   Metabolomics

Current understanding of the human microbiome

(2018) Jack A Gilbert et al.   NATURE MEDICINE

The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients

(2018) Vyara Matson et al.   SCIENCE

Pharmacomicrobiomics: a novel route towards personalized medicine?

(2018) Marwah Doestzada et al.   Protein & Cell

American Gut: an Open Platform for Citizen Science Microbiome Research

(2018) Daniel McDonald et al.   mSystems

Microbial exposure and human health

(2018) Anukriti Sharma et al.   CURRENT OPINION IN MICROBIOLOGY

Drug pharmacomicrobiomics and toxicomicrobiomics: from scattered reports to systematic studies of drug–microbiome interactions

(2018) Ramy K. Aziz et al.   Expert Opinion on Drug Metabolism & Toxicology

Gut Microbiota Modulation Attenuated the Hypolipidemic Effect of Simvastatin in High-Fat/Cholesterol-Diet Fed Mice

(2017) Xuyun He et al.   JOURNAL OF PROTEOME RESEARCH

A communal catalogue reveals Earth’s multiscale microbial diversity

(2017) Luke R. Thompson et al.   NATURE

Moving beyond microbiome-wide associations to causal microbe identification

(2017) Neeraj K. Surana et al.   NATURE

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

(2017) Hao Wu et al.   NATURE MEDICINE

Gut microbiota modulation of chemotherapy efficacy and toxicity

(2017) James L. Alexander et al.   Nature Reviews Gastroenterology & Hepatology

Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women

(2017) Nichole R. Klatt et al.   SCIENCE

Chemical transformation of xenobiotics by the human gut microbiota

(2017) Nitzan Koppel et al.   SCIENCE

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

(2017) V. Gopalakrishnan et al.   SCIENCE

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

Cancer prevention from the perspective of global cancer burden patterns

(2017) Hiroki Nagai et al.   Journal of Thoracic Disease

Genetic Determinants of the Gut Microbiome in UK Twins

(2016) Julia K. Goodrich et al.   Cell Host & Microbe

Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models

(2016) Sheila Annie Peters et al.   CLINICAL PHARMACOKINETICS

Microbiome-wide association studies link dynamic microbial consortia to disease

(2016) Jack A. Gilbert et al.   NATURE

A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

(2016) Hubert Plovier et al.   NATURE MEDICINE

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

(2016) Alexandra Zhernakova et al.   SCIENCE

Population-level analysis of gut microbiome variation

(2016) Gwen Falony et al.   SCIENCE

Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis

(2016) Krista Dubin et al.   Nature Communications

Revised Estimates for the Number of Human and Bacteria Cells in the Body

(2016) Ron Sender et al.   PLOS BIOLOGY

Biochemical characterisation of the neuraminidase pool of the human gut symbiont Akkermansia muciniphila

(2015) Kun Huang et al.   CARBOHYDRATE RESEARCH

Personalized Nutrition by Prediction of Glycemic Responses

(2015) David Zeevi et al.   CELL

Epidemiology of Adverse Drug Reactions in Europe: A Review of Recent Observational Studies

(2015) Jacoline C. Bouvy et al.   DRUG SAFETY

The influence of gut microbiota on drug metabolism and toxicity

(2015) Houkai Li et al.   Expert Opinion on Drug Metabolism & Toxicology

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

(2015) Kristoffer Forslund et al.   NATURE

Genome-Wide Association Studies of the Human Gut Microbiota

(2015) Emily R. Davenport et al.   PLoS One

Pharmacogenomics of Human Uridine Diphospho-Glucuronosyltransferases and Clinical Implications

(2014) C Guillemette et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

In Vitro Fermentation of Lactulose by Human Gut Bacteria

(2014) Bingyong Mao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Pharmacomicrobiomics: The Impact of Human Microbiome Variations on Systems Pharmacology and Personalized Therapeutics

(2014) Marwa ElRakaiby et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Substantial decreases in the number and diversity of microbiota during chemotherapy-induced gastrointestinal mucositis in a rat model

(2014) Margot Fijlstra et al.   SUPPORTIVE CARE IN CANCER

Pharmacometabolomics: Implications for Clinical Pharmacology and Systems Pharmacology

(2013) R Kaddurah-Daouk et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Genetic and chemical characterization of ibuprofen degradation by Sphingomonas Ibu-2

(2013) R. W. Murdoch et al.   MICROBIOLOGY-SGM

Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

(2013) N. Iida et al.   SCIENCE

The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

(2013) S. Viaud et al.   SCIENCE

Gut Pharmacomicrobiomics: the tip of an iceberg of complex interactions between drugs and gut-associated microbes

(2013) Rama Saad et al.   Gut Pathogens

A meta-metabolome network of carbohydrate metabolism: Interactions between gut microbiota and host

(2012) Maziya Ibrahim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Developing a metagenomic view of xenobiotic metabolism

(2012) Henry J. Haiser et al.   PHARMACOLOGICAL RESEARCH

The Effect of Low-Pressure Carbonation on the Heat Inactivation ofEscherichia coli

(2011) Wannaporn KLANGPETCH et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

PharmacoMicrobiomics or how bugs modulate drugs: an educational initiative to explore the effects of human microbiome on drugs

(2011) Ramy K Aziz et al.   BMC BIOINFORMATICS

Six-Week Consumption of a Wild Blueberry Powder Drink Increases Bifidobacteria in the Human Gut

(2011) Stefano Vendrame et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Bacteroides uniformis Is a Putative Bacterial Species Associated with the Degradation of the Isoflavone Genistein in Human Feces

(2011) Mathieu Renouf et al.   JOURNAL OF NUTRITION

Daidzein and Genistein Are Converted to Equol and 5-Hydroxy-Equol by Human Intestinal Slackia isoflavoniconvertens in Gnotobiotic Rats

(2011) Anastasia Matthies et al.   JOURNAL OF NUTRITION

Role of Intestinal Bacteria in Gliadin-Induced Changes in Intestinal Mucosa: Study in Germ-Free Rats

(2011) Jana Cinova et al.   PLoS One

Enteric Microbiome Metabolites Correlate with Response to Simvastatin Treatment

(2011) Rima Kaddurah-Daouk et al.   PLoS One

Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors

(2010) A. K. Benson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

(2010) B. D. Wallace et al.   SCIENCE

Metabolism of azo dyes by human skin microbiota

(2009) R. L. Stingley et al.   JOURNAL OF MEDICAL MICROBIOLOGY

The human superorganism – Of microbes and men

(2009) Roy D. Sleator   MEDICAL HYPOTHESES

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

(2009) T. A. Clayton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Review: Chemotherapy-induced diarrhea: pathophysiology, frequency and guideline-based management

(2009) Alexander Stein et al.   Therapeutic Advances in Medical Oncology

Metabolomics: A Global Biochemical Approach to Drug Response and Disease

(2008) Rima Kaddurah-Daouk et al.   Annual Review of Pharmacology and Toxicology

Microbial hydrolysis of steviol glycosides

(2008) A.G. Renwick et al.   FOOD AND CHEMICAL TOXICOLOGY

The gastrointestinal microbiota as a site for the biotransformation of drugs

(2008) Tiago Sousa et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS