Mechanistic and structural insight into promiscuity based metabolism of cardiac drug digoxin by gut microbial enzyme

A novel approach for the prediction of species-specific biotransformation of xenobiotic/drug molecules by the human gut microbiota

(2017) Ashok K. Sharma et al.   Scientific Reports

The microbial pharmacists within us: a metagenomic view of xenobiotic metabolism

(2016) Peter Spanogiannopoulos et al.   NATURE REVIEWS MICROBIOLOGY

Exploring the biological consequences of conformational changes in aspartame models containing constrained analogues of phenylalanine

(2015) Adriano Mollica et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Structure-based functional annotation of hypothetical proteins from Candida dubliniensis: a quest for potential drug targets

(2014) Kundan Kumar et al.   3 Biotech

Predicting and Manipulating Cardiac Drug Inactivation by the Human Gut Bacterium Eggerthella lenta

(2013) H. J. Haiser et al.   SCIENCE

Is It Time for a Metagenomic Basis of Therapeutics?

(2012) H. J. Haiser et al.   SCIENCE

Metagenomics: Facts and Artifacts, and Computational Challenges

(2010) John C. Wooley et al.   JOURNAL OF COMPUTER SCIENCE AND TECHNOLOGY

Computer-aided drug design platform using PyMOL

(2010) Markus A. Lill et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

CDD: a Conserved Domain Database for the functional annotation of proteins

(2010) A. Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

(2010) B. D. Wallace et al.   SCIENCE

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Gut microbiota: a potential new territory for drug targeting

(2008) Wei Jia et al.   NATURE REVIEWS DRUG DISCOVERY