Bookmarking by histone methylation ensures chromosomal integrity during mitosis

Phosphorylation of CENP-A on serine 7 does not control centromere function

(2019) Viviana Barra et al.   Nature Communications

CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation

(2019) Markus Seibert et al.   JOURNAL OF CELL BIOLOGY

Posttranslational modifications of CENP-A: marks of distinction

(2018) Shashank Srivastava et al.   CHROMOSOMA

KDM2B is a histone H3K79 demethylase and induces transcriptional repression via sirtuin-1–mediated chromatin silencing

(2018) Joo-Young Kang et al.   FASEB JOURNAL

Middle-Down Characterization of the Cell Cycle Dependence of Histone H4 Posttranslational Modifications and Proteoforms

(2018) Tingting Jiang et al.   PROTEOMICS

Aurora A-dependent CENP-A phosphorylation at inner centromeres protects bioriented chromosomes against cohesion fatigue

(2018) Grégory Eot-Houllier et al.   Nature Communications

SETDB2 Links E2A-PBX1 to Cell-Cycle Dysregulation in Acute Leukemia through CDKN2C Repression

(2018) Chiou-Hong Lin et al.   Cell Reports

Abstract 3135: Single-cell RNA sequencing identifies macrophage-specific expression signatures associated with phagocytosis of multiple myeloma after treatment with cIAP antagonist

(2018) Nicholas Banovich et al.   CANCER RESEARCH

Study of mitotic chromatin supports a model of bookmarking by histone modifications and reveals nucleosome deposition patterns

(2018) Elisheva Javasky et al.   GENOME RESEARCH

Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing

(2018) Muhammad Shoaib et al.   Nature Communications

Cell cycle-resolved chromatin proteomics reveals the extent of mitotic preservation of the genomic regulatory landscape

(2018) Paul Adrian Ginno et al.   Nature Communications

Tackling malignant melanoma epigenetically: histone lysine methylation

(2018) Elias Orouji et al.   Clinical Epigenetics

Centromere and Pericentromere Transcription: Roles and Regulation … in Sickness and in Health

(2018) Ksenia Smurova et al.   Frontiers in Genetics

Aurora Kinase B Phosphorylates Histone H3.3 at Serine 31 during Mitosis in Mammalian Cells

(2017) Miao Li et al.   JOURNAL OF MOLECULAR BIOLOGY

Set2 methyltransferase facilitates cell cycle progression by maintaining transcriptional fidelity

(2017) Raghuvar Dronamraju et al.   NUCLEIC ACIDS RESEARCH

LSD1 promotes S-phase entry and tumorigenesis via chromatin co-occupation with E2F1 and selective H3K9 demethylation

(2017) Y He et al.   ONCOGENE

Transcriptional landscape of the human cell cycle

(2017) Yin Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitotic transcription and waves of gene reactivation during mitotic exit

(2017) Katherine C. Palozola et al.   SCIENCE

Mechanisms Regulating PRC2 Recruitment and Enzymatic Activity

(2017) Daniel Holoch et al.   TRENDS IN BIOCHEMICAL SCIENCES

Repo-Man/PP1 regulates heterochromatin formation in interphase

(2017) Inês J. de Castro et al.   Nature Communications

CRL4 DCAF8 Ubiquitin Ligase Targets Histone H3K79 and Promotes H3K9 Methylation in the Liver

(2017) Gaofeng Li et al.   Cell Reports

Epigenetic countermarks in mitotic chromosome condensation

(2017) Karel H. M. van Wely et al.   Nucleus

Epigenetic countermarks in mitotic chromosome condensation

(2017) Karel H. M. van Wely et al.   Nucleus

Epigenetic Regulation of Cellular Senescence and Aging

(2017) Corinne Sidler et al.   Frontiers in Genetics

Dual Chromatin and Cytoskeletal Remodeling by SETD2

(2016) In Young Park et al.   CELL

The upstreams and downstreams of H3K79 methylation by DOT1L

(2016) Hanneke Vlaming et al.   CHROMOSOMA

KAT7/HBO1/MYST2 Regulates CENP-A Chromatin Assembly by Antagonizing Suv39h1-Mediated Centromere Inactivation

(2016) Jun-ichirou Ohzeki et al.   DEVELOPMENTAL CELL

H3K36 methyltransferases as cancer drug targets: rationale and perspectives for inhibitor development

(2016) David S Rogawski et al.   Future Medicinal Chemistry

Chromosome missegregation during anaphase triggers p53 cell cycle arrest through histone H3.3 Ser31 phosphorylation

(2016) Edward H. Hinchcliffe et al.   NATURE CELL BIOLOGY

H3K9me3 demethylase Kdm4d facilitates the formation of pre-initiative complex and regulates DNA replication

(2016) Rentian Wu et al.   NUCLEIC ACIDS RESEARCH

Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy

(2016) Ludovica Morera et al.   Clinical Epigenetics

Writers, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break Repair

(2016) Godelieve Smeenk et al.   Frontiers in Genetics

Histone demethylases in chromatin biology and beyond

(2015) E. Dimitrova et al.   EMBO REPORTS

Two distinct modes for propagation of histone PTMs across the cell cycle

(2015) Constance Alabert et al.   GENES & DEVELOPMENT

The lysine demethylase LSD1 is required for nuclear envelope formation at the end of mitosis

(2015) A. Schooley et al.   JOURNAL OF CELL SCIENCE

Identification of the Post-translational Modifications Present in Centromeric Chromatin

(2015) Aaron O. Bailey et al.   MOLECULAR & CELLULAR PROTEOMICS

Histone H4 Lysine 20 (H4K20) Methylation, Expanding the Signaling Potential of the Proteome One Methyl Moiety at a Time

(2015) Rick van Nuland et al.   MOLECULAR & CELLULAR PROTEOMICS

Targeting Polycomb systems to regulate gene expression: modifications to a complex story

(2015) Neil P. Blackledge et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone exchange, chromatin structure and the regulation of transcription

(2015) Swaminathan Venkatesh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Constitutive heterochromatin formation and transcription in mammals

(2015) Nehmé Saksouk et al.   Epigenetics & Chromatin

Epigenetic regulatory functions of DNA modifications: 5-methylcytosine and beyond

(2015) Achim Breiling et al.   Epigenetics & Chromatin

How the cell cycle impacts chromatin architecture and influences cell fate

(2015) Yiqin Ma et al.   Frontiers in Genetics

Sensing core histone phosphorylation — A matter of perfect timing

(2014) Anna Sawicka et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Histone lysine methylation and chromatin replication

(2014) Carlos Rivera et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

AF10 Regulates Progressive H3K79 Methylation and HOX Gene Expression in Diverse AML Subtypes

(2014) Aniruddha J. Deshpande et al.   CANCER CELL

Chromatin dynamics from S-phase to mitosis: contributions of histone modifications

(2014) Detlef Doenecke   CELL AND TISSUE RESEARCH

The histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle

(2014) Wootae Kim et al.   CELL CYCLE

Chromatin dynamics: H3K4 methylation and H3 variant replacement during development and in cancer

(2014) Moonmoon Deb et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nucleosome Structure and Function

(2014) Robert K. McGinty et al.   CHEMICAL REVIEWS

Histone H4 Lys 20 Monomethylation of the CENP-A Nucleosome Is Essential for Kinetochore Assembly

(2014) Tetsuya Hori et al.   DEVELOPMENTAL CELL

Mitotic Accumulation of Dimethylated Lysine 79 of Histone H3 Is Important for Maintaining Genome Integrity During Mitosis in Human Cells

(2014) Brent J. Guppy et al.   GENETICS

Cyclin E-CDK2 Protein Phosphorylates Plant Homeodomain Finger Protein 8 (PHF8) and Regulates Its Function in the Cell Cycle

(2014) Liping Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polycomb Repressive Complex 2 and H3K27me3 Cooperate with H3K9 Methylation To Maintain Heterochromatin Protein 1  at Chromatin

(2014) J. Boros et al.   MOLECULAR AND CELLULAR BIOLOGY

A SET-domain-independent role of WRAD complex in cell-cycle regulatory function of mixed lineage leukemia

(2014) Aamir Ali et al.   NUCLEIC ACIDS RESEARCH

KDM4C (GASC1) lysine demethylase is associated with mitotic chromatin and regulates chromosome segregation during mitosis

(2014) Ilana Kupershmit et al.   NUCLEIC ACIDS RESEARCH

A Cascade of Histone Modifications Induces Chromatin Condensation in Mitosis

(2014) Bryan J. Wilkins et al.   SCIENCE

Human-Chromatin-Related Protein Interactions Identify a Demethylase Complex Required for Chromosome Segregation

(2014) Edyta Marcon et al.   Cell Reports

Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G1/S transition

(2013) Masaharu Kogure et al.   CANCER LETTERS

Aurora B Defines Its Own Chromosomal Targeting by Opposing the Recruitment of the Phosphatase Scaffold Repo-Man

(2013) Junbin Qian et al.   CURRENT BIOLOGY

Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin

(2013) M. Hahn et al.   GENES & DEVELOPMENT

The G2/M Regulator Histone Demethylase PHF8 Is Targeted for Degradation by the Anaphase-Promoting Complex Containing CDC20

(2013) H.-J. Lim et al.   MOLECULAR AND CELLULAR BIOLOGY

H4K20 methylation regulates quiescence and chromatin compaction

(2013) Adam G. Evertts et al.   MOLECULAR BIOLOGY OF THE CELL

Occupying Chromatin: Polycomb Mechanisms for Getting to Genomic Targets, Stopping Transcriptional Traffic, and Staying Put

(2013) Jeffrey A. Simon et al.   MOLECULAR CELL

Polycomb-Dependent H3K27me1 and H3K27me2 Regulate Active Transcription and Enhancer Fidelity

(2013) Karin J. Ferrari et al.   MOLECULAR CELL

Histone H4 Lysine 20 methylation: key player in epigenetic regulation of genomic integrity

(2013) S. Jorgensen et al.   NUCLEIC ACIDS RESEARCH

Cell cycle control across the eukaryotic kingdom

(2013) Hirofumi Harashima et al.   TRENDS IN CELL BIOLOGY

Methylation of Histone H3 on Lysine 79 Associates with a Group of Replication Origins and Helps Limit DNA Replication Once per Cell Cycle

(2013) Haiqing Fu et al.   PLoS Genetics

Putting CENP-A in its place

(2012) Madison E. Stellfox et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Jmjd5, an H3K36me2 histone demethylase, modulates embryonic cell proliferation through the regulation of Cdkn1a expression

(2012) A. Ishimura et al.   DEVELOPMENT

In vivo Polycomb kinetics and mitotic chromatin binding distinguish stem cells from differentiated cells

(2012) J. P. Fonseca et al.   GENES & DEVELOPMENT

PR-Set7 and H4K20me1: at the crossroads of genome integrity, cell cycle, chromosome condensation, and transcription

(2012) D. B. Beck et al.   GENES & DEVELOPMENT

Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4

(2012) H.-M. Herz et al.   GENES & DEVELOPMENT

Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation

(2012) Fangwei Wang et al.   JOURNAL OF CELL BIOLOGY

Control of Proinflammatory Gene Programs by Regulated Trimethylation and Demethylation of Histone H4K20

(2012) Joshua D. Stender et al.   MOLECULAR CELL

Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact

(2012) Joshua C. Black et al.   MOLECULAR CELL

The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

(2012) Mar Carmena et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Understanding the language of Lys36 methylation at histone H3

(2012) Eric J. Wagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone modifications and mitosis: countermarks, landmarks, and bookmarks

(2012) Fangwei Wang et al.   TRENDS IN CELL BIOLOGY

A Polycomb Group Protein Is Retained at Specific Sites on Chromatin in Mitosis

(2012) Nicole E. Follmer et al.   PLoS Genetics

Methylation-mediated control of aurora kinase B and Haspin with epigenetically modified histone H3 N-terminal peptides

(2011) Areum Han et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Chromatin Signaling to Kinetochores: Transregulation of Dam1 Methylation by Histone H2B Ubiquitination

(2011) John A. Latham et al.   CELL

A Positive Feedback Loop Involving Haspin and Aurora B Promotes CPC Accumulation at Centromeres in Mitosis

(2011) Fangwei Wang et al.   CURRENT BIOLOGY

Histone H3K4 methylation keeps centromeres open for business

(2011) Kaitlin M Stimpson et al.   EMBO JOURNAL

Chromatin landscape

(2011) Joshua C. Black et al.   Epigenetics

The diverse functions of Dot1 and H3K79 methylation

(2011) A. T. Nguyen et al.   GENES & DEVELOPMENT

Histone H3 trimethylation at lysine 36 is associated with constitutive and facultative heterochromatin

(2011) S. Chantalat et al.   GENOME RESEARCH

Deficiency of H3K79 Histone Methyltransferase Dot1-like Protein (DOT1L) Inhibits Cell Proliferation

(2011) Wootae Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

H3K36 Methylation Antagonizes PRC2-mediated H3K27 Methylation

(2011) Wen Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Peek into the Complex Realm of Histone Phosphorylation

(2011) T. Banerjee et al.   MOLECULAR AND CELLULAR BIOLOGY

Deacetylation and methylation at histone H3 lysine 9 (H3K9) coordinate chromosome condensation during cell cycle progression

(2011) Jin-Ah Park et al.   MOLECULES AND CELLS

Condensin association with histone H2A shapes mitotic chromosomes

(2011) Kenji Tada et al.   NATURE

Mapping and analysis of chromatin state dynamics in nine human cell types

(2011) Jason Ernst et al.   NATURE

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation

(2011) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone code pathway involving H3 S28 phosphorylation and K27 acetylation activates transcription and antagonizes polycomb silencing

(2011) P. N. I. Lau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Covalent modifications of histones during mitosis and meiosis

(2010) Dazhong Xu et al.   CELL CYCLE

Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore

(2010) Jan H Bergmann et al.   EMBO JOURNAL

A phospho/methyl switch at histone H3 regulates TFIID association with mitotic chromosomes

(2010) Radhika A Varier et al.   EMBO JOURNAL

Epigenetic dynamics across the cell cycle

(2010) Tony Bou Kheir et al.   Essays in Biochemistry

LSD1 is required for chromosome segregation during mitosis

(2010) Shuang Lv et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Acetylation of core histones in response to HDAC inhibitors is diminished in mitotic HeLa cells

(2010) Jason S. Patzlaff et al.   EXPERIMENTAL CELL RESEARCH

Mixed lineage leukemia: histone H3 lysine 4 methyltransferases from yeast to human

(2010) Shivani Malik et al.   FEBS Journal

Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression

(2010) S. Wu et al.   GENES & DEVELOPMENT

Phosphorylation of serine-10 of histone H3 shields modified lysine-9 selectively during mitosis

(2010) Young Sun Jeong et al.   GENES TO CELLS

Kinetics of Re-establishing H3K79 Methylation Marks in Global Human Chromatin

(2010) Steve M. M. Sweet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CLLD8/KMT1F Is a Lysine Methyltransferase That Is Important for Chromosome Segregation

(2010) Claire Falandry et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PR-Set7-mediated monomethylation of histone H4 lysine 20 at specific genomic regions induces transcriptional repression

(2010) Lauren M. Congdon et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Polycomb Group Protein Displacement and Gene Activation through MSK-Dependent H3K27me3S28 Phosphorylation

(2010) Simmi Suman Gehani et al.   MOLECULAR CELL

Conserved Antagonism between JMJD2A/KDM4A and HP1γ during Cell Cycle Progression

(2010) Joshua C. Black et al.   MOLECULAR CELL

CRL4Cdt2-Mediated Destruction of the Histone Methyltransferase Set8 Prevents Premature Chromatin Compaction in S Phase

(2010) Richard C. Centore et al.   MOLECULAR CELL

CRL4Cdt2 Regulates Cell Proliferation and Histone Gene Expression by Targeting PR-Set7/Set8 for Degradation

(2010) Tarek Abbas et al.   MOLECULAR CELL

PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression

(2010) Wen Liu et al.   NATURE

Phosphorylation of the CPC by Cdk1 promotes chromosome bi-orientation

(2010) Tatsuya Tsukahara et al.   NATURE

Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development

(2010) Hank H. Qi et al.   NATURE

Discovery and characterization of chromatin states for systematic annotation of the human genome

(2010) Jason Ernst et al.   NATURE BIOTECHNOLOGY

Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres

(2010) Roderick J O'Sullivan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation

(2010) D. A. Hsia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two Histone Marks Establish the Inner Centromere and Chromosome Bi-Orientation

(2010) Yuya Yamagishi et al.   SCIENCE

Survivin Reads Phosphorylated Histone H3 Threonine 3 to Activate the Mitotic Kinase Aurora B

(2010) Alexander E. Kelly et al.   SCIENCE

Histone H3 Thr-3 Phosphorylation by Haspin Positions Aurora B at Centromeres in Mitosis

(2010) Fangwei Wang et al.   SCIENCE

Chromatin Higher-order Structure and Dynamics

(2010) C. L. Woodcock et al.   Cold Spring Harbor Perspectives in Biology

The multiple facets of histone H4-lysine 20 methylationThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.

(2009) Hongbo Yang et al.   Biochemistry and Cell Biology

Dynamic association of MLL1, H3K4 trimethylation with chromatin and Hox gene expression during the cell cycle

(2009) Bibhu P. Mishra et al.   FEBS Journal

DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions

(2009) Suhasni Gopalakrishnan et al.   HUMAN MOLECULAR GENETICS

Mechanisms of transcriptional repression by histone lysine methylation

(2009) Philip Hublitz et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

G2 histone methylation is required for the proper segregation of chromosomes

(2009) R. Heit et al.   JOURNAL OF CELL SCIENCE

Monomethylation of Histone H4-Lysine 20 Is Involved in Chromosome Structure and Stability and Is Essential for Mouse Development

(2009) H. Oda et al.   MOLECULAR AND CELLULAR BIOLOGY

Chromatin Binding of SRp20 and ASF/SF2 and Dissociation from Mitotic Chromosomes Is Modulated by Histone H3 Serine 10 Phosphorylation

(2009) Rebecca J. Loomis et al.   MOLECULAR CELL

Role of the polycomb protein EED in the propagation of repressive histone marks

(2009) Raphael Margueron et al.   NATURE

Nonredundant Requirement for Multiple Histone Modifications for the Early Anaphase Release of the Mitotic Exit Regulator Cdc14 from Nucleolar Chromatin

(2009) William W. Hwang et al.   PLoS Genetics

Histone deacetylase 3 is required for centromeric H3K4 deacetylation and sister chromatid cohesion

(2008) G. Eot-Houllier et al.   GENES & DEVELOPMENT

Phosphorylation of H3S10 Blocks the Access of H3K9 by Specific Antibodies and Histone Methyltransferase

(2008) Qing Duan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polycomb Group Protein-associated Chromatin Is Reproduced in Post-mitotic G1Phase and Is Required for S Phase Progression

(2008) Takahiro Aoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DOT1L/KMT4 Recruitment and H3K79 Methylation Are Ubiquitously Coupled with Gene Transcription in Mammalian Cells

(2008) D. J. Steger et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone Ubiquitination: Triggering Gene Activity

(2008) Vikki M. Weake et al.   MOLECULAR CELL