4.4 Review

Chromatin dynamics from S-phase to mitosis: contributions of histone modifications

Journal

CELL AND TISSUE RESEARCH
Volume 356, Issue 3, Pages 467-475

Publisher

SPRINGER
DOI: 10.1007/s00441-014-1873-1

Keywords

Histone modification; Centromeric chromatin; Mitotic chromatin; S-phase chromatin; Heterochromatin

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This review focuses on the major protein moiety of chromosomes, i.e., the histone proteins, on the contribution of their posttranslational modification to structural and functional chromatin dynamics, on the acetylation and methylation of lysine residues, and on the phosphorylation of serine or threonine with respect to various steps during the cell cycle.

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