Shikimic Acid Promotes Oligodendrocyte Precursor Cell Differentiation and Accelerates Remyelination in Mice

Remyelination therapies: a new direction and challenge in multiple sclerosis

(2017) Jason R. Plemel et al.   NATURE REVIEWS DRUG DISCOVERY

MiR-30a Positively Regulates the Inflammatory Response of Microglia in Experimental Autoimmune Encephalomyelitis

(2017) Xue Fang et al.   Neuroscience Bulletin

Acute axonal damage in three different murine models of multiple sclerosis: A comparative approach

(2016) Katharina Marie Höflich et al.   BRAIN RESEARCH

Shikimic acid inhibits LPS-induced cellular pro-inflammatory cytokines and attenuates mechanical hyperalgesia in mice

(2016) Thallita Kelly Rabelo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The roles of extracellular related-kinases 1 and 2 signaling in CNS myelination

(2016) David Gonsalvez et al.   NEUROPHARMACOLOGY

Programmed Death Ligand-1 on Microglia Regulates Th1 Differentiation via Nitric Oxide in Experimental Autoimmune Encephalomyelitis

(2016) Jingxia Hu et al.   Neuroscience Bulletin

NG2-glia and their functions in the central nervous system

(2015) L. Dimou et al.   GLIA

In Vitro Neuroprotective Effect of Shikimic Acid Against Hydrogen Peroxide-Induced Oxidative Stress

(2015) Thallita Kelly Rabelo et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Sox2 Sustains Recruitment of Oligodendrocyte Progenitor Cells following CNS Demyelination and Primes Them for Differentiation during Remyelination

(2015) Chao Zhao et al.   JOURNAL OF NEUROSCIENCE

MSX3 Switches Microglia Polarization and Protects from Inflammation-Induced Demyelination

(2015) Z. Yu et al.   JOURNAL OF NEUROSCIENCE

Glia Disease and Repair—Remyelination

(2015) Robin J.M. Franklin et al.   Cold Spring Harbor Perspectives in Biology

Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue

(2014) Nicolas Snaidero et al.   CELL

Remyelination and Multiple Sclerosis: Therapeutic Approaches and Challenges

(2014) Meredith D. Hartley et al.   Current Neurology and Neuroscience Reports

Oligodendrocyte progenitors: Adult stem cells of the central nervous system?

(2014) A.H. Crawford et al.   EXPERIMENTAL NEUROLOGY

Protective effect of coconut water concentrate and its active component shikimic acid against hydroperoxide mediated oxidative stress through suppression of NF-κB and activation of Nrf2 pathway

(2014) Krishnendu Manna et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cyclin-Dependent Kinase 5 Mediates Adult OPC Maturation and Myelin Repair through Modulation of Akt and GsK-3  Signaling

(2014) F. Luo et al.   JOURNAL OF NEUROSCIENCE

Glial response during cuprizone-induced de- and remyelination in the CNS: lessons learned

(2014) Viktoria Gudi et al.   Frontiers in Cellular Neuroscience

SOX17 is expressed in regenerating oligodendrocytes in experimental models of demyelination and in multiple sclerosis

(2013) N. M. Moll et al.   GLIA

A functional role of NMDA receptor in regulating the differentiation of oligodendrocyte precursor cells and remyelination

(2013) Cui Li et al.   GLIA

Diosgenin promotes oligodendrocyte progenitor cell differentiation through estrogen receptor-mediated ERK1/2 activation to accelerate remyelination

(2012) Lin Xiao et al.   GLIA

Remyelination Therapy for Multiple Sclerosis

(2012) Michael B. Keough et al.   Neurotherapeutics

Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)

(2011) Cris S Constantinescu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Erk1/2 MAPK and mTOR signaling sequentially regulates progression through distinct stages of oligodendrocyte differentiation

(2011) Hebe M. Guardiola-Diaz et al.   GLIA

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

(2011) Michelle C. Mendoza et al.   TRENDS IN BIOCHEMICAL SCIENCES

CNS-Resident Glial Progenitor/Stem Cells Produce Schwann Cells as well as Oligodendrocytes during Repair of CNS Demyelination

(2010) Malgorzata Zawadzka et al.   Cell Stem Cell

ERK1 and ERK2 are required for radial glial maintenance and cortical lamination

(2010) Osamu Imamura et al.   GENES TO CELLS

Signals to promote myelin formation and repair

(2010) Carla Taveggia et al.   Nature Reviews Neurology

Activation of the Mammalian Target of Rapamycin (mTOR) Is Essential for Oligodendrocyte Differentiation

(2009) W. A. Tyler et al.   JOURNAL OF NEUROSCIENCE

Akt Signals through the Mammalian Target of Rapamycin Pathway to Regulate CNS Myelination

(2009) S. P. Narayanan et al.   JOURNAL OF NEUROSCIENCE

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

(2008) T. Kuhlmann et al.   BRAIN

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE