Diosgenin promotes oligodendrocyte progenitor cell differentiation through estrogen receptor-mediated ERK1/2 activation to accelerate remyelination

Switching ofN-Methyl-d-aspartate (NMDA) Receptor-favorite Intracellular Signal Pathways from ERK1/2 Protein to p38 Mitogen-activated Protein Kinase Leads to Developmental Changes in NMDA Neurotoxicity

(2011) Lin Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ERK2 Mitogen-Activated Protein Kinase Regulates the Timing of Oligodendrocyte Differentiation

(2011) S. L. Fyffe-Maricich et al.   JOURNAL OF NEUROSCIENCE

Reactive Astrocytes Inhibit the Survival and Differentiation of Oligodendrocyte Precursor Cells by Secreted TNF-α

(2011) Zhida Su et al.   JOURNAL OF NEUROTRAUMA

Diosgenin, a Steroidal Saponin, Inhibits Migration and Invasion of Human Prostate Cancer PC-3 Cells by Reducing Matrix Metalloproteinases Expression

(2011) Pin-Shern Chen et al.   PLoS One

KV7/KCNQ Channels Are Functionally Expressed in Oligodendrocyte Progenitor Cells

(2011) Wei Wang et al.   PLoS One

Roles of NG2 glial cells in diseases of the central nervous system

(2011) Jian-Ping Xu et al.   Neuroscience Bulletin

The constitutive production of the endocannabinoid 2-arachidonoylglycerol participates in oligodendrocyte differentiation

(2010) Oscar Gomez et al.   GLIA

Sp1 phosphorylation is involved in myelin basic protein gene transcription

(2010) Lili Guo et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Glucocorticoid Rapidly Enhances NMDA-Evoked Neurotoxicity by Attenuating the NR2A-Containing NMDA Receptor-Mediated ERK1/2 Activation

(2010) Lin Xiao et al.   MOLECULAR ENDOCRINOLOGY

17β-estradiol protects male mice from cuprizone-induced demyelination and oligodendrocyte loss

(2010) Lorelei C. Taylor et al.   NEUROBIOLOGY OF DISEASE

Netrin 1 and Dcc regulate oligodendrocyte process branching and membrane extension via Fyn and RhoA

(2009) S. Rajasekharan et al.   DEVELOPMENT

Impact of sex steroids on neuroinflammatory processes and experimental multiple sclerosis

(2009) Markus Kipp et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Remyelination — An effective means of neuroprotection

(2009) Charlotte C. Bruce et al.   HORMONES AND BEHAVIOR

Diosgenin targets Akt-mediated prosurvival signaling in human breast cancer cells

(2009) Sowmyalakshmi Srinivasan et al.   INTERNATIONAL JOURNAL OF CANCER

Activation of the Mammalian Target of Rapamycin (mTOR) Is Essential for Oligodendrocyte Differentiation

(2009) W. A. Tyler et al.   JOURNAL OF NEUROSCIENCE

Cancer Chemopreventive and Therapeutic Effects of Diosgenin, a Food Saponin

(2009) Jayadev Raju et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Novel effects of diosgenin on skin aging

(2009) Yayoi Tada et al.   STEROIDS

Remyelination protects axons from demyelination-associated axon degeneration

(2008) K. A. Irvine et al.   BRAIN

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

(2008) T. Kuhlmann et al.   BRAIN

17β-estradiol and progesterone prevent cuprizone provoked demyelination of corpus callosum in male mice

(2008) Peter Acs et al.   GLIA

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE

Platelet-derived growth factor-AA mediates oligodendrocyte lineage differentiation through activation of extracellular signal-regulated kinase signaling pathway

(2007) J.-G. Hu et al.   NEUROSCIENCE