Glial response during cuprizone-induced de- and remyelination in the CNS: lessons learned

The translational biology of remyelination: Past, present, and future

(2014) Robin J. M. Franklin et al.   GLIA

Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro

(2013) Vibol Chhor et al.   BRAIN BEHAVIOR AND IMMUNITY

Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain

(2013) Maj-Linda B Selenica et al.   Journal of Neuroinflammation

A regenerative approach to the treatment of multiple sclerosis

(2013) Vishal A. Deshmukh et al.   NATURE

Cuprizone [Bis(Cyclohexylidenehydrazide)] is Selectively Toxic for Mature Oligodendrocytes

(2013) Karelle Bénardais et al.   NEUROTOXICITY RESEARCH

Investigation of Sequential Growth Factor Delivery during Cuprizone Challenge in Mice Aimed to Enhance Oligodendrogliogenesis and Myelin Repair

(2013) Jennifer K. Sabo et al.   PLoS One

Origin and differentiation of microglia

(2013) Florent Ginhoux et al.   Frontiers in Cellular Neuroscience

Factors regulating microglia activation

(2013) Katrin Kierdorf et al.   Frontiers in Cellular Neuroscience

Astrocyte TNFR2 is required for CXCL12-mediated regulation of oligodendrocyte progenitor proliferation and differentiation within the adult CNS

(2012) Jigisha R. Patel et al.   ACTA NEUROPATHOLOGICA

Astrogliosis During Acute and Chronic Cuprizone Demyelination and Implications for Remyelination

(2012) Norah Hibbits et al.   ASN Neuro

Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination

(2012) Thomas Skripuletz et al.   BRAIN

Cuprizone-induced demyelination in the rat cerebral cortex and thyroid hormone effects on cortical remyelination

(2012) Lucas Silvestroff et al.   EXPERIMENTAL NEUROLOGY

Regional Heterogeneity of Cuprizone-Induced Demyelination: Topographical Aspects of the Midline of the Corpus Callosum

(2012) T. Schmidt et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Inflammatory Response and Chemokine Expression in the White Matter Corpus Callosum and Gray Matter Cortex Region During Cuprizone-Induced Demyelination

(2012) J. P. Buschmann et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Glial cells in (patho)physiology

(2012) Vladimir Parpura et al.   JOURNAL OF NEUROCHEMISTRY

IL-17-Induced Act1-Mediated Signaling Is Critical for Cuprizone-Induced Demyelination

(2012) Z. Kang et al.   JOURNAL OF NEUROSCIENCE

Abbreviated exposure to cuprizone is sufficient to induce demyelination and oligodendrocyte loss

(2012) Vivian Doan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Review: Activation patterns of microglia and their identification in the human brain

(2012) D. Boche et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Microglia in the developing brain: A potential target with lifetime effects

(2012) G. Jean Harry et al.   NEUROTOXICOLOGY

Lipopolysaccharide delays demyelination and promotes oligodendrocyte precursor proliferation in the central nervous system

(2011) Thomas Skripuletz et al.   BRAIN BEHAVIOR AND IMMUNITY

BLBP-expression in astrocytes during experimental demyelination and in human multiple sclerosis lesions

(2011) M. Kipp et al.   BRAIN BEHAVIOR AND IMMUNITY

Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)

(2011) Cris S Constantinescu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Chemokines in health and disease

(2011) Dayanidhi Raman et al.   EXPERIMENTAL CELL RESEARCH

Identification of a microglia phenotype supportive of remyelination

(2011) Marta Olah et al.   GLIA

Matrix Metalloproteinases and Their Tissue Inhibitors in Cuprizone-Induced Demyelination and Remyelination of Brain White and Gray Matter

(2011) Jelena Škuljec et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Remyelination Is Altered by Bone Morphogenic Protein Signaling in Demyelinated Lesions

(2011) J. K. Sabo et al.   JOURNAL OF NEUROSCIENCE

Myelin Regeneration in Multiple Sclerosis: Targeting Endogenous Stem Cells

(2011) Jeffrey K. Huang et al.   Neurotherapeutics

Spatial and Temporal Profiles of Growth Factor Expression during CNS Demyelination Reveal the Dynamics of Repair Priming

(2011) Viktoria Gudi et al.   PLoS One

Macrophage Polarization in Health and Disease

(2011) Luca Cassetta et al.   TheScientificWorldJOURNAL

Zfp488 promotes oligodendrocyte differentiation of neural progenitor cells in adult mice after demyelination

(2011) Mangala M. Soundarapandian et al.   Scientific Reports

Age-Related and Cuprizone-Induced Changes in Myelin and Transcription Factor Gene Expression and in Oligodendrocyte Cell Densities in the Rostral Corpus Callosum of Mice

(2010) J. Ronald Doucette et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

How factors secreted from astrocytes impact myelin repair

(2010) Craig S. Moore et al.   JOURNAL OF NEUROSCIENCE RESEARCH

CXCR2-positive neutrophils are essential for cuprizone-induced demyelination: relevance to multiple sclerosis

(2010) LiPing Liu et al.   NATURE NEUROSCIENCE

Beneficial Effects of Minocycline on Cuprizone Induced Cortical Demyelination

(2010) Thomas Skripuletz et al.   NEUROCHEMICAL RESEARCH

Role of Cytokines as Mediators and Regulators of Microglial Activity in Inflammatory Demyelination of the CNS

(2010) Tobias D. Merson et al.   NEUROMOLECULAR MEDICINE

Remyelination after cuprizone induced demyelination is accelerated in mice deficient in the polysialic acid synthesizing enzyme St8siaIV

(2010) P.N. Koutsoudaki et al.   NEUROSCIENCE

Effects of Fumaric Acids on Cuprizone Induced Central Nervous System De- and Remyelination in the Mouse

(2010) Darius Moharregh-Khiabani et al.   PLoS One

CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination

(2010) J. R. Patel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oligodendrocytes: biology and pathology

(2009) Monika Bradl et al.   ACTA NEUROPATHOLOGICA

The cuprizone animal model: new insights into an old story

(2009) Markus Kipp et al.   ACTA NEUROPATHOLOGICA

Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

(2009) Sha Mi et al.   ANNALS OF NEUROLOGY

Microglial Physiology: Unique Stimuli, Specialized Responses

(2009) Richard M. Ransohoff et al.   Annual Review of Immunology

SJL Mice Exposed to Cuprizone Intoxication Reveal Strain and Gender Pattern Differences in Demyelination

(2009) Lorelei C. Taylor et al.   BRAIN PATHOLOGY

Cerebellar Cortical Demyelination in the Murine Cuprizone Model

(2009) Thomas Skripuletz et al.   BRAIN PATHOLOGY

Regional differences between grey and white matter in cuprizone induced demyelination

(2009) Viktoria Gudi et al.   BRAIN RESEARCH

Cuprizone effect on myelination, astrogliosis and microglia attraction in the mouse basal ganglia

(2009) Friederike Pott et al.   BRAIN RESEARCH

Leukemia inhibitory factor regulates the timing of oligodendrocyte development and myelination in the postnatal optic nerve

(2009) Tomoko Ishibashi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cuprizone induces similar demyelination in male and female C57BL/6 mice and results in disruption of the estrous cycle

(2009) Lorelei C. Taylor et al.   JOURNAL OF NEUROSCIENCE RESEARCH

In toxic demyelination oligodendroglial cell death occurs early and is FAS independent

(2009) Amke Hesse et al.   NEUROBIOLOGY OF DISEASE

Remyelination capacity of the MS brain decreases with disease chronicity

(2009) T. Goldschmidt et al.   NEUROLOGY

Chronic toxic demyelination in the central nervous system leads to axonal damage despite remyelination

(2009) Maren Lindner et al.   NEUROSCIENCE LETTERS

Progressive multiple sclerosis

(2009) Monika Bradl et al.   Seminars in Immunopathology

Cortical Demyelination Is Prominent in the Murine Cuprizone Model and Is Strain-Dependent

(2008) Thomas Skripuletz et al.   AMERICAN JOURNAL OF PATHOLOGY

Astrocytes in multiple sclerosis: A product of their environment

(2008) A. Nair et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: Implications for the lesion pathogenesis of multiple sclerosis

(2008) Sonja Ortler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Being a mouse in a man's world: what TMEV has taught us about human disease

(2008) Kristen et al.   Frontiers in Bioscience-Landmark

Leukemia inhibitory factor signaling modulates both central nervous system demyelination and myelin repair

(2008) Mark P. Marriott et al.   GLIA

Matrix metalloproteinase-2 is involved in myelination of dorsal root ganglia neurons

(2008) Helmar C. Lehmann et al.   GLIA

The life, death, and replacement of oligodendrocytes in the adult CNS

(2008) Dana M. McTigue et al.   JOURNAL OF NEUROCHEMISTRY

Expression and regulation of matrix metalloproteinase-12 in experimental autoimmune encephalomyelitis and by bone marrow derived macrophages in vitro

(2008) Angelika Goncalves DaSilva et al.   JOURNAL OF NEUROIMMUNOLOGY

MHC class II exacerbates demyelination in vivo independently of T cells

(2008) Meenaxi M. Hiremath et al.   JOURNAL OF NEUROIMMUNOLOGY

Leukemia inhibitory factor modulates production of inflammatory mediators and myelin phagocytosis by macrophages

(2008) J HENDRIKS et al.   JOURNAL OF NEUROIMMUNOLOGY

Inhibition of p53 Transcriptional Activity: A Potential Target for Future Development of Therapeutic Strategies for Primary Demyelination

(2008) J. Li et al.   JOURNAL OF NEUROSCIENCE

Gas6 Deficiency Increases Oligodendrocyte Loss and Microglial Activation in Response to Cuprizone-Induced Demyelination

(2008) M. D. Binder et al.   JOURNAL OF NEUROSCIENCE

Cuprizone treatment induces demyelination and astrocytosis in the mouse hippocampus

(2008) Akvile Norkute et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency

(2008) Siming Shen et al.   NATURE NEUROSCIENCE

Activation of Inflammatory Response by a Combination of Growth Factors in Cuprizone-Induced Demyelinated Brain Leads to Myelin Repair

(2008) Juan Carlos Biancotti et al.   NEUROCHEMICAL RESEARCH

Demyelination of the hippocampus is prominent in the cuprizone model

(2008) Paraskevi N. Koutsoudaki et al.   NEUROSCIENCE LETTERS

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark

Multiple roles of chemokine CXCL12 in the central nervous system: A migration from immunology to neurobiology

(2007) M LI et al.   PROGRESS IN NEUROBIOLOGY