Dysregulation of CRMP2 Post-Translational Modifications Drive Its Pathological Functions

Redox Signaling Mechanisms in Nervous System Development

(2018) Mauricio Olguín-Albuerne et al.   ANTIOXIDANTS & REDOX SIGNALING

Structural Insights into the Altering Function of CRMP2 by Phosphorylation

(2018) Takuya Sumi et al.   CELL STRUCTURE AND FUNCTION

Across the blood-brain barrier: Neurotherapeutic screening and characterization of naringenin as a novel CRMP-2 inhibitor in the treatment of Alzheimer's disease using bioinformatics and computational tools

(2018) Maryam Lawal et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Mapping protein interactions of sodium channel Na V 1.7 using epitope‐tagged gene‐targeted mice

(2018) Alexandros H Kanellopoulos et al.   EMBO JOURNAL

The microglial reaction signature revealed by RNAseq from individual mice

(2018) Hélène Hirbec et al.   GLIA

Increased Levels of Circulating Glial Fibrillary Acidic Protein and Collapsin Response Mediator Protein-2 Autoantibodies in the Acute Stage of Spinal Cord Injury Predict the Subsequent Development of Neuropathic Pain

(2018) Georgene W. Hergenroeder et al.   JOURNAL OF NEUROTRAUMA

Unconventional Signaling by Extracellular CRMP2: Possible Role as an Atypical Neurotransmitter?

(2018) Aubin Moutal et al.   NEUROSCIENCE

CRMP2–Neurofibromin Interface Drives NF1-related Pain

(2018) Aubin Moutal et al.   NEUROSCIENCE

Extracellular Application of CRMP2 Increases Cytoplasmic Calcium through NMDA Receptors

(2018) Cecilia Castillo et al.   NEUROSCIENCE

Inhibition of the Ubc9 E2 SUMO-conjugating enzyme–CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain

(2018) Liberty François-Moutal et al.   PAIN

CRMP2-binding compound, edonerpic maleate, accelerates motor function recovery from brain damage

(2018) Hiroki Abe et al.   SCIENCE

Probenecid Disrupts a Novel Pannexin 1-Collapsin Response Mediator Protein 2 Interaction and Increases Microtubule Stability

(2018) Xiaoxue Xu et al.   Frontiers in Cellular Neuroscience

Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation

(2018) Yiyan Zheng et al.   Nature Communications

Morphoregulatory functions of the RNA-binding motif protein 3 in cell spreading, polarity and migration

(2018) J. Pilotte et al.   Scientific Reports

Molecular Architecture of the Mouse Nervous System

(2018) Amit Zeisel et al.   CELL

Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channels

(2018) Liberty François-Moutal et al.   Channels

CRMP2 Hyperphosphorylation is Characteristic of Alzheimer's Disease and not a Feature Common to Other Neurodegenerative Diseases

(2018) Ritchie Williamson et al.   JOURNAL OF ALZHEIMERS DISEASE

Carboxymethylation of CRMP2 is associated with decreased Schwann cell myelination efficiency

(2018) Fuminori Saitoh et al.   NEUROSCIENCE RESEARCH

Inhibition of collapsin response mediator protein-2 phosphorylation ameliorates motor phenotype of ALS model mice expressing SOD1G93A

(2018) Yurika Numata-Uematsu et al.   NEUROSCIENCE RESEARCH

Disruption of the psychiatric risk gene Ankyrin 3 enhances microtubule dynamics through GSK3/CRMP2 signaling

(2018) Jacob C. Garza et al.   Translational Psychiatry

Peroxiredoxin interaction with the cytoskeletal-regulatory protein CRMP2: Investigation of a putative redox relay

(2018) Paul E. Pace et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetic suppression of collapsin response mediator protein 2 phosphorylation improves outcome in methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson’s model mice

(2018) Kentaro Togashi et al.   GENES TO CELLS

Semaphorins and Their Receptors: From Axonal Guidance to Atherosclerosis

(2018) Shuhong Hu et al.   Frontiers in Physiology

Evaluation of quality of life in adults with neurofibromatosis 1 (NF1) using the Impact of NF1 on Quality Of Life (INF1-QOL) questionnaire

(2017) Rosalie E Ferner et al.   Health and Quality of Life Outcomes

CRMP2 Phosphorylation Drives Glioblastoma Cell Proliferation

(2017) Aubin Moutal et al.   MOLECULAR NEUROBIOLOGY

Blocking CRMP2 SUMOylation reverses neuropathic pain

(2017) A Moutal et al.   MOLECULAR PSYCHIATRY

Collapsin response mediator protein-2 plays a major protective role in acute axonal degeneration

(2017) JanC Koch et al.   Neural Regeneration Research

Dissecting the role of the CRMP2–neurofibromin complex on pain behaviors

(2017) Aubin Moutal et al.   PAIN

CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide

(2017) Aubin Moutal et al.   PAIN

Elucidating crosstalk mechanisms between phosphorylation and O-GlcNAcylation

(2017) Aneika C. Leney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis

(2017) Brian T. D. Tobe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for CRMP2-induced axonal microtubule formation

(2017) Shinsuke Niwa et al.   Scientific Reports

Sphingosine-1-Phosphate and the S1P3 Receptor Initiate Neuronal Retraction via RhoA/ROCK Associated with CRMP2 Phosphorylation

(2017) Serena Quarta et al.   Frontiers in Molecular Neuroscience

A Systematic Strategy for Discovering a Therapeutic Drug for Alzheimer’s Disease and Its Target Molecule

(2017) Zhiyou Yang et al.   Frontiers in Pharmacology

What is the evidence that tau pathology spreads through prion-like propagation?

(2017) Amrit Mudher et al.   Acta Neuropathologica Communications

Quantitative Phosphoproteomics Reveals a Role for Collapsin Response Mediator Protein 2 in PDGF-Induced Cell Migration

(2017) Adil R. Sarhan et al.   Scientific Reports

Inhibition of CRMP2 phosphorylation repairs CNS by regulating neurotrophic and inhibitory responses

(2016) Jun Nagai et al.   EXPERIMENTAL NEUROLOGY

A novel mouse model for the identification of thioredoxin-1 protein interactions

(2016) Michelle L. Booze et al.   FREE RADICAL BIOLOGY AND MEDICINE

CRMP1 and CRMP2 have synergistic but distinct roles in dendritic development

(2016) Hiroko Makihara et al.   GENES TO CELLS

Collapsin Response Mediator Protein-2 (CRMP2) is a Plausible Etiological Factor and Potential Therapeutic Target in Alzheimer’s Disease: Comparison and Contrast with Microtubule-Associated Protein Tau

(2016) Kenneth Hensley et al.   JOURNAL OF ALZHEIMERS DISEASE

Deletion of Crmp4 attenuates CSPG-induced inhibition of axonal growth and induces nociceptive recovery after spinal cord injury

(2016) Jun Nagai et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A Tale of the Good and Bad: Remodeling of the Microtubule Network in the Brain by Cdk5

(2016) Kavita Shah et al.   MOLECULAR NEUROBIOLOGY

Sensitization of Ion Channels Contributes to Central and Peripheral Dysfunction in Neurofibromatosis Type 1

(2016) Aubin Moutal et al.   MOLECULAR NEUROBIOLOGY

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

(2016) Ye Zhang et al.   NEURON

Moving towards effective therapeutic strategies for Neuronal Ceroid Lipofuscinosis

(2016) Ryan D. Geraets et al.   Orphanet Journal of Rare Diseases

(S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology

(2016) Aubin Moutal et al.   PAIN

Hierarchical CRMP2 posttranslational modifications control NaV1.7 function

(2016) Erik T. Dustrude et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain-specific Crmp2 deletion leads to neuronal development deficits and behavioural impairments in mice

(2016) Hongsheng Zhang et al.   Nature Communications

Increased phosphorylation of collapsin response mediator protein-2 at Thr514 correlates with β-amyloid burden and synaptic deficits in Lewy body dementias

(2016) Huayang Xing et al.   Molecular Brain

The DPYSL2 gene connects mTOR and schizophrenia

(2016) X Pham et al.   Translational Psychiatry

Recombinant Nogo-66 via soluble expression with SUMO fusion in Escherichia coli inhibits neurite outgrowth in vitro

(2015) Xiaoyong Dai et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Genetics of the neuronal ceroid lipofuscinoses (Batten disease)

(2015) Sara E. Mole et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Towards a new understanding of NCL pathogenesis

(2015) Jonathan D. Cooper et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Phosphorylation of a splice variant of collapsin response mediator protein 2 in the nucleus of tumour cells links cyclin dependent kinase-5 to oncogenesis

(2015) Nicola J. Grant et al.   BMC CANCER

CRMP5 Controls Glioblastoma Cell Proliferation and Survival through Notch-Dependent Signaling

(2015) A. Moutal et al.   CANCER RESEARCH

Silencing collapsin response mediator protein-2 reprograms macrophage phenotype and improves infarct healing in experimental myocardial infarction model

(2015) Long-Shu Zhou et al.   Journal of Inflammation-London

Colocalization of phosphorylated forms of WAVE1, CRMP2, and tau in Alzheimer's disease model mice: Involvement of Cdk5 phosphorylation and the effect of ATRA treatment

(2015) Naoto Watamura et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Mechanisms of local invasion in enteroendocrine tumors: Identification of novel candidate cytoskeleton-associated proteins in an experimental mouse model by a proteomic approach and validation in human tumors

(2015) Christophe Couderc et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5

(2015) Aubin Moutal et al.   MOLECULAR NEUROBIOLOGY

CRMPs: critical molecules for neurite morphogenesis and neuropsychiatric diseases

(2015) T T Quach et al.   MOLECULAR PSYCHIATRY

Regulation of cytoskeletal dynamics by redox signaling and oxidative stress: implications for neuronal development and trafficking

(2015) Carlos Wilson et al.   Frontiers in Cellular Neuroscience

Cerebrospinal fluid-derived Semaphorin3B orients neuroepithelial cell divisions in the apicobasal axis

(2015) Elise Arbeille et al.   Nature Communications

Prolyl Isomerase Pin1 Regulates Axon Guidance by Stabilizing CRMP2A Selectively in Distal Axons

(2015) Martin Balastik et al.   Cell Reports

CRMP4 and CRMP2 Interact to Coordinate Cytoskeleton Dynamics, Regulating Growth Cone Development and Axon Elongation

(2015) Minghui Tan et al.   NEURAL PLASTICITY

Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain

(2014) N. K. H. Lim et al.   HUMAN MOLECULAR GENETICS

Collapsin Response Mediator Protein 2 (CRMP2) Interacts withN-Methyl-d-aspartate (NMDA) Receptor and Na+/Ca2+Exchanger and Regulates Their Functional Activity

(2014) Tatiana Brustovetsky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Specific Binding of Lacosamide to Collapsin Response Mediator Protein 2 (CRMP2) and Direct Impairment of its Canonical Function: Implications for the Therapeutic Potential of Lacosamide

(2014) Sarah M. Wilson et al.   MOLECULAR NEUROBIOLOGY

CRMP2

(2014) Jacque P.K. Ip et al.   NEUROSCIENTIST

The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth

(2014) Sarah M. Wilson et al.   Frontiers in Cellular Neuroscience

Collapsin response mediator proteins: Potential diagnostic and prognostic biomarkers in cancers (Review)

(2014) FEI TAN et al.   Oncology Letters

Functional Variants in DPYSL2 Sequence Increase Risk of Schizophrenia and Suggest a Link to mTOR Signaling

(2014) Yaping Liu et al.   G3-Genes Genomes Genetics

SUMOylation alters CRMP2 regulation of calcium influx in sensory neurons

(2013) Weina Ju et al.   Channels

Regulation of centrosome movements by Numb and the Collapsin Response Mediator Protein during Drosophila sensory progenitor asymmetric division

(2013) Bertrand Jauffred et al.   DEVELOPMENT

Phosphorylation of Dpsyl2 (CRMP2) and Dpsyl3 (CRMP4) is required for positioning of caudal primary motor neurons in the zebrafish spinal cord

(2013) Rii Morimura et al.   Developmental Neurobiology

Identification of a Dithiol-disulfide Switch in Collapsin Response Mediator Protein 2 (CRMP2) That Is Toggled in a Model of Neuronal Differentiation

(2013) Manuela Gellert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CRMP2 Protein SUMOylation Modulates NaV1.7 Channel Trafficking

(2013) Erik T. Dustrude et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping CRMP3 domains involved in dendrite morphogenesis and voltage-gated calcium channel regulation

(2013) T. T. Quach et al.   JOURNAL OF CELL SCIENCE

Insights into the oligomerization of CRMPs: crystal structure of human collapsin response mediator protein 5

(2013) Rajesh Ponnusamy et al.   JOURNAL OF NEUROCHEMISTRY

A Derivative of the Brain Metabolite Lanthionine Ketimine Improves Cognition and Diminishes Pathology in the 3×Tg-AD Mouse Model of Alzheimer Disease

(2013) Kenneth Hensley et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

CRMP2 Tethers Kainate Receptor Activity to Cytoskeleton Dynamics during Neuronal Maturation

(2013) J. M. Marques et al.   JOURNAL OF NEUROSCIENCE

Amelioration of β-amyloid-induced cognitive dysfunction and hippocampal axon degeneration by curcumin is associated with suppression of CRMP-2 hyperphosphorylation

(2013) Yunliang Wang et al.   NEUROSCIENCE LETTERS

Amyloid-β25–35 induces impairment of cognitive function and long-term potentiation through phosphorylation of collapsin response mediator protein 2

(2013) Toshinari Isono et al.   NEUROSCIENCE RESEARCH

Collapsin response mediator protein 2 is involved in regulating breast cancer progression

(2013) Kazuhiro Shimada et al.   Breast Cancer

Detection of autoantibodies against heat shock proteins and collapsin response mediator proteins in autoimmune retinopathy

(2013) Grazyna Adamus et al.   BMC Ophthalmology

Insight into the role of CRMP2 (collapsin response mediator protein 2) in T lymphocyte migration

(2013) Pascale Giraudon et al.   Cell Adhesion & Migration

Autism-specific maternal autoantibodies recognize critical proteins in developing brain

(2013) D Braunschweig et al.   Translational Psychiatry

Limiting multiple sclerosis related axonopathy by blocking Nogo receptor and CRMP-2 phosphorylation

(2012) Steven Petratos et al.   BRAIN

Disruption of NMDAR–CRMP-2 signaling protects against focal cerebral ischemic damage in the rat middle cerebral artery occlusion model

(2012) Joel M. Brittain et al.   Channels

Phosphorylation of CRMP2 is involved in proper bifurcation of the apical dendrite of hippocampal CA1 pyramidal neurons

(2012) Emi Niisato et al.   Developmental Neurobiology

Cdk5-mediated phosphorylation of CRMP-2 enhances its interaction with CaV2.2

(2012) Joel M. Brittain et al.   FEBS LETTERS

Collapsin response mediator protein-2 phosphorylation promotes the reversible retraction of oligodendrocyte processes in response to non-lethal oxidative stress

(2012) Agata Fernández-Gamba et al.   JOURNAL OF NEUROCHEMISTRY

Phosphorylation of CRMP2 (Collapsin Response Mediator Protein 2) Is Involved in Proper Dendritic Field Organization

(2012) N. Yamashita et al.   JOURNAL OF NEUROSCIENCE

Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system

(2011) Gabrièle Piaton et al.   BRAIN

Further insights into the antinociceptive potential of a peptide disrupting the N-type calcium channel–CRMP-2 signaling complex

(2011) Sarah M. Wilson et al.   Channels

Collapsin Response Mediator Proteins (CRMPs) Are a New Class of Microtubule-associated Protein (MAP) That Selectively Interacts with Assembled Microtubules via a Taxol-sensitive Binding Interaction

(2011) Pao-Chun Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroprotection against Traumatic Brain Injury by a Peptide Derived from the Collapsin Response Mediator Protein 2 (CRMP2)

(2011) Joel M. Brittain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of CNS Remyelination by the Presence of Semaphorin 3A

(2011) Y. A. Syed et al.   JOURNAL OF NEUROSCIENCE

Cdk5-Mediated Phosphorylation of Axin Directs Axon Formation during Cerebral Cortex Development

(2011) W.-Q. Fang et al.   JOURNAL OF NEUROSCIENCE

Collapsin Response Mediator Protein-2: An Emerging Pathologic Feature and Therapeutic Target for Neurodisease Indications

(2011) Kenneth Hensley et al.   MOLECULAR NEUROBIOLOGY

Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders

(2011) Leslie Crews et al.   Molecular Neurodegeneration

Thioredoxin Mediates Oxidation-Dependent Phosphorylation of CRMP2 and Growth Cone Collapse

(2011) A. Morinaka et al.   Science Signaling

Collapsin Response Mediator Protein-2 (Crmp2) Regulates Trafficking by Linking Endocytic Regulatory Proteins to Dynein Motors

(2010) Juliati Rahajeng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In SilicoDocking and Electrophysiological Characterization of Lacosamide Binding Sites on Collapsin Response Mediator Protein-2 Identifies a Pocket Important in Modulating Sodium Channel Slow Inactivation

(2010) Yuying Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CRMP5 Interacts with Tubulin to Inhibit Neurite Outgrowth, Thereby Modulating the Function of CRMP2

(2010) S. Brot et al.   JOURNAL OF NEUROSCIENCE

Proteomic Identification of Binding Partners for the Brain Metabolite Lanthionine Ketimine (LK) and Documentation of LK Effects on Microglia and Motoneuron Cell Cultures

(2010) K. Hensley et al.   JOURNAL OF NEUROSCIENCE

Collapsin Response Mediator Protein 4a (CRMP4a) Is Upregulated in Motoneurons of Mutant SOD1 Mice and Can Trigger Motoneuron Axonal Degeneration and Cell Death

(2010) L. Duplan et al.   JOURNAL OF NEUROSCIENCE

Expression profiling identifies new function of collapsin response mediator protein 4 as a metastasis-suppressor in prostate cancer

(2010) X Gao et al.   ONCOGENE

Collapsin response mediator protein-2 regulates neurite formation by modulating tubulin GTPase activity

(2009) Young Chan Chae et al.   CELLULAR SIGNALLING

Semaphorin3A Signaling Mediated by Fyn-dependent Tyrosine Phosphorylation of Collapsin Response Mediator Protein 2 at Tyrosine 32

(2009) Yutaka Uchida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Atypical Role for Collapsin Response Mediator Protein 2 (CRMP-2) in Neurotransmitter Release via Interaction with Presynaptic Voltage-gated Calcium Channels

(2009) Joel M. Brittain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of Collapsin Response Mediator Protein 2 on Tyr-479 Regulates CXCL12-induced T Lymphocyte Migration

(2009) Michel Varrin-Doyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of N-type voltage-gated calcium channels (Cav2.2) and transmitter release by collapsin response mediator protein-2 (CRMP-2) in sensory neurons

(2009) X. X. Chi et al.   JOURNAL OF CELL SCIENCE

Signaling pathway adaptations and novel protein kinase A substrates related to behavioral sensitization to cocaine

(2009) Amy C. Boudreau et al.   JOURNAL OF NEUROCHEMISTRY

CRMP-2 directly binds to cytoplasmic dynein and interferes with its activity

(2009) Nariko Arimura et al.   JOURNAL OF NEUROCHEMISTRY

Protein product ofCLN6gene responsible for variant late-onset infantile neuronal ceroid lipofuscinosis interacts with CRMP-2

(2009) Jared W. Benedict et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer

(2009) R Tabarés-Seisdedos et al.   MOLECULAR PSYCHIATRY

Calpain-truncated CRMP-3 and -4 contribute to potassium deprivation-induced apoptosis of cerebellar granule neurons

(2009) Wei Liu et al.   PROTEOMICS

Extensive Expression of Collapsin Response Mediator Protein 5 (CRMP5) is a Specific Marker of High-grade Lung Neuroendocrine Carcinoma

(2008) David Meyronet et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Neurofibromatosis Type 1 (NF1) Tumor Suppressor, Neurofibromin, Regulates the Neuronal Differentiation of PC12 Cells via Its Associating Protein, CRMP-2

(2008) Siriporn Patrakitkomjorn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Block of Sensory Neuronal Voltage-Gated Sodium Channels by Lacosamide [(2R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide], Lidocaine, and Carbamazepine

(2008) P. L. Sheets et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Calcium Channel Regulation and Presynaptic Plasticity

(2008) William A. Catterall et al.   NEURON

Cytosolic O-glycosylation is abundant in nerve terminals

(2003) Robert N. Cole et al.   JOURNAL OF NEUROCHEMISTRY