The DPYSL2 gene connects mTOR and schizophrenia

Docosahexaenoic Acid Promotes Axon Outgrowth by Translational Regulation of Tau and Collapsin Response Mediator Protein 2 Expression

(2016) Toshinari Mita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian Target of Rapamycin (mTOR) Tagging Promotes Dendritic Branch Variability through the Capture of Ca2+/Calmodulin-dependent Protein Kinase II α (CaMKIIα) mRNAs by the RNA-binding Protein HuD

(2015) Natasha M. Sosanya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CRMPs: critical molecules for neurite morphogenesis and neuropsychiatric diseases

(2015) T T Quach et al.   MOLECULAR PSYCHIATRY

A cell-penetrating ester of the neural metabolite lanthionine ketimine stimulates autophagy through the mTORC1 pathway: Evidence for a mechanism of action with pharmacological implications for neurodegenerative pathologies

(2015) Marni E. Harris-White et al.   NEUROBIOLOGY OF DISEASE

PANTHER version 10: expanded protein families and functions, and analysis tools

(2015) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

The protein interactome of collapsin response mediator protein-2 (CRMP2/DPYSL2) reveals novel partner proteins in brain tissue

(2015) Daniel Martins-de-Souza et al.   Proteomics Clinical Applications

Infection and Inflammation in Schizophrenia and Bipolar Disorder: A Genome Wide Study for Interactions with Genetic Variation

(2015) Dimitrios Avramopoulos et al.   PLoS One

ZNF804A Transcriptional Networks in Differentiating Neurons Derived from Induced Pluripotent Stem Cells of Human Origin

(2015) Jian Chen et al.   PLoS One

A Targeted Multiplexed Proteomic Investigation Identifies Ketamine-Induced Changes in Immune Markers in Rat Serum and Expression Changes in Protein Kinases/Phosphatases in Rat Brain

(2014) Hendrik Wesseling et al.   JOURNAL OF PROTEOME RESEARCH

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner

(2014) Rachel Miloslavski et al.   Journal of Molecular Cell Biology

Functional Variants in DPYSL2 Sequence Increase Risk of Schizophrenia and Suggest a Link to mTOR Signaling

(2014) Yaping Liu et al.   G3-Genes Genomes Genetics

Expression ofZNF804Ain Human Brain and Alterations in Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

(2014) Ran Tao et al.   JAMA Psychiatry

mTOR signaling and its roles in normal and abnormal brain development

(2014) Nobuyuki Takei et al.   Frontiers in Molecular Neuroscience

Is the mTOR-signalling cascade disrupted in Schizophrenia?

(2013) Anand Gururajan et al.   JOURNAL OF NEUROCHEMISTRY

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Phosphorylation of CRMP2 (Collapsin Response Mediator Protein 2) Is Involved in Proper Dendritic Field Organization

(2012) N. Yamashita et al.   JOURNAL OF NEUROSCIENCE

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

NeurphologyJ: An automatic neuronal morphology quantification method and its application in pharmacological discovery

(2011) Shinn-Ying Ho et al.   BMC BIOINFORMATICS

Collapsin Response Mediator Protein-2: An Emerging Pathologic Feature and Therapeutic Target for Neurodisease Indications

(2011) Kenneth Hensley et al.   MOLECULAR NEUROBIOLOGY

Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders

(2011) Leslie Crews et al.   Molecular Neurodegeneration

mTOR couples cellular nutrient sensing to organismal metabolic homeostasis

(2011) Jessica J. Howell et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Linkage and association on 8p21.2-p21.1 in schizophrenia

(2010) M. Daniele Fallin et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

The Neuroproteomics of Schizophrenia

(2010) Jane A. English et al.   BIOLOGICAL PSYCHIATRY

Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia

(2010) Daniel Martins-de-Souza et al.   JOURNAL OF PSYCHIATRIC RESEARCH

mTOR and cancer: many loops in one pathway

(2009) Alejo Efeyan et al.   CURRENT OPINION IN CELL BIOLOGY

Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia

(2009) Daniel Martins-de-Souza et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Specification of Neuronal Polarity Regulated by Local Translation of CRMP2 and Tau via the mTOR-p70S6K Pathway

(2009) Tsuyoshi Morita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ELAV Protein HuD Stimulates Cap-Dependent Translation in a Poly(A)- and eIF4A-Dependent Manner

(2009) Akira Fukao et al.   MOLECULAR CELL

Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia

(2008) Daniel Martins-de-Souza et al.   JOURNAL OF PSYCHIATRIC RESEARCH

The TSC-mTOR Pathway Mediates Translational Activation of TOP mRNAs by Insulin Largely in a Raptor- or Rictor-Independent Manner

(2008) I. Patursky-Polischuk et al.   MOLECULAR AND CELLULAR BIOLOGY

Comprehensive detection of human terminal oligo-pyrimidine (TOP) genes and analysis of their characteristics

(2008) Riu Yamashita et al.   NUCLEIC ACIDS RESEARCH

Proteomic analysis reveals protein changes within layer 2 of the insular cortex in schizophrenia

(2008) Kyla Pennington et al.   PROTEOMICS

Role of mTOR in physiology and pathology of the nervous system

(2007) Lukasz Swiech et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS