Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain

A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin

(2013) Maria Damiano et al.   HUMAN MOLECULAR GENETICS

Decreased Metabolism in the Cerebral Cortex in Early-Stage Huntington's Disease: A Possible Biomarker of Disease Progression?

(2013) Hyeeun Shin et al.   Journal of Clinical Neurology

Therapeutic effects of CuII(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis

(2013) Erin J. McAllum et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Energy dysfunction in Huntington’s disease: insights from PGC-1α, AMPK, and CKB

(2012) Tz-Chuen Ju et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Huntingtonʼs disease

(2012) Ainhi D. Ha et al.   CURRENT OPINION IN NEUROLOGY

Shaping the role of mitochondria in the pathogenesis of Huntington's disease

(2012) Veronica Costa et al.   EMBO JOURNAL

18F-FDG PET uptake in the pre-Huntington disease caudate affects the time-to-onset independently of CAG expansion size

(2012) Andrea Ciarmiello et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Cdk5-mediated phosphorylation of CRMP-2 enhances its interaction with CaV2.2

(2012) Joel M. Brittain et al.   FEBS LETTERS

Collapsin Response Mediator Proteins Regulate Neuronal Development and Plasticity by Switching Their Phosphorylation Status

(2012) Naoya Yamashita et al.   MOLECULAR NEUROBIOLOGY

Mutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's disease

(2011) P. Hemachandra Reddy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Perturbation of the Akt/Gsk3-β signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs

(2011) Clare L. van Eyk et al.   HUMAN MOLECULAR GENETICS

Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease

(2011) U. P. Shirendeb et al.   HUMAN MOLECULAR GENETICS

Early Alterations of Brain Cellular Energy Homeostasis in Huntington Disease Models

(2011) Fanny Mochel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role for Akt and glycogen synthase kinase-3 as integrators of dopamine and serotonin neurotransmission in mental health

(2011) Jean-Martin Beaulieu   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders

(2011) Leslie Crews et al.   Molecular Neurodegeneration

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

(2011) Wenjun Song et al.   NATURE MEDICINE

The dynamic role of beta-catenin in synaptic plasticity

(2011) Kimberly A. Maguschak et al.   NEUROPHARMACOLOGY

Combined Treatment with the Mood Stabilizers Lithium and Valproate Produces Multiple Beneficial Effects in Transgenic Mouse Models of Huntington's Disease

(2011) Chi-Tso Chiu et al.   NEUROPSYCHOPHARMACOLOGY

Mutant huntingtin-impaired degradation of β-catenin causes neurotoxicity in Huntington's disease

(2010) Juliette D Godin et al.   EMBO JOURNAL

Modulation of energy deficiency in Huntington's disease via activation of the peroxisome proliferator-activated receptor gamma

(2010) Ming-Chang Chiang et al.   HUMAN MOLECULAR GENETICS

Evidence that glycogen synthase kinase-3 isoforms have distinct substrate preference in the brain

(2010) Marc P. M. Soutar et al.   JOURNAL OF NEUROCHEMISTRY

Increased CRMP2 Phosphorylation is Observed in Alzheimers Disease; Does this Tell us Anything About Disease Development?

(2009) M. Soutar et al.   Current Alzheimer Research

Functional imaging in Huntington's disease

(2009) Jane S. Paulsen   EXPERIMENTAL NEUROLOGY

An Atypical Role for Collapsin Response Mediator Protein 2 (CRMP-2) in Neurotransmitter Release via Interaction with Presynaptic Voltage-gated Calcium Channels

(2009) Joel M. Brittain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutant huntingtin and glycogen synthase kinase 3-β accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease

(2009) Antonio Valencia et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Glycogen synthase kinase 3β (GSK3β) in tumorigenesis and cancer chemotherapy

(2008) Jia Luo   CANCER LETTERS

Effects of overexpression of Huntingtin proteins on mitochondrial integrity

(2008) Hongmin Wang et al.   HUMAN MOLECULAR GENETICS

N-Terminal Mutant Huntingtin Associates with Mitochondria and Impairs Mitochondrial Trafficking

(2008) A. L. Orr et al.   JOURNAL OF NEUROSCIENCE