Veins and Arteries Build Hierarchical Branching Patterns Differently: Bottom-Up versus Top-Down

Vascular deficiency of Smad4 causes arteriovenous malformations: a mouse model of Hereditary Hemorrhagic Telangiectasia

(2018) Angela M. Crist et al.   ANGIOGENESIS

Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations

(2018) Bàrbara Laviña et al.   DEVELOPMENT

Development and Function of theDrosophilaTracheal System

(2018) Shigeo Hayashi et al.   GENETICS

Development and Function of theDrosophilaTracheal System

(2018) Shigeo Hayashi et al.   GENETICS

Single-cell analysis of early progenitor cells that build coronary arteries

(2018) Tianying Su et al.   NATURE

A molecular atlas of cell types and zonation in the brain vasculature

(2018) Michael Vanlandewijck et al.   NATURE

Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells

(2018) Mark F Sabbagh et al.   eLife

Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos

(2018) Bart Weijts et al.   Nature Communications

DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12–CXCR4 signaling axis

(2017) Andrew H. Chang et al.   GENES & DEVELOPMENT

Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling

(2017) Yi Jin et al.   NATURE CELL BIOLOGY

Endothelial Notch signalling limits angiogenesis via control of artery formation

(2017) Sana S. Hasan et al.   NATURE CELL BIOLOGY

Dll4 and Notch signalling couples sprouting angiogenesis and artery formation

(2017) Mara E. Pitulescu et al.   NATURE CELL BIOLOGY

Endoglin controls blood vessel diameter through endothelial cell shape changes in response to haemodynamic cues

(2017) Wade W. Sugden et al.   NATURE CELL BIOLOGY

Vascular heterogeneity and specialization in development and disease

(2017) Michael Potente et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

NOTCH1 is a mechanosensor in adult arteries

(2017) Julia J. Mack et al.   Nature Communications

Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification

(2017) Jennifer S. Fang et al.   Nature Communications

Neuronal sFlt1 and Vegfaa determine venous sprouting and spinal cord vascularization

(2017) Raphael Wild et al.   Nature Communications

Do as I say, Not(ch) as I do: Lateral control of cell fate

(2017) Marika Sjöqvist et al.   DEVELOPMENTAL BIOLOGY

Hemodynamic Control of Endothelial Cell Fates in Development

(2016) Guillermo García-Cardeña et al.   Annual Review of Cell and Developmental Biology

Endothelial Mechanosignaling: Does One Sensor Fit All?

(2016) Chris Givens et al.   ANTIOXIDANTS & REDOX SIGNALING

Alk1 controls arterial endothelial cell migration in lumenized vessels

(2016) Elizabeth R. Rochon et al.   DEVELOPMENT

Initiation of stem cell differentiation involves cell cycle-dependent regulation of developmental genes by Cyclin D

(2016) Siim Pauklin et al.   GENES & DEVELOPMENT

Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia

(2016) Nicolas Baeyens et al.   JOURNAL OF CELL BIOLOGY

Endothelial fluid shear stress sensing in vascular health and disease

(2016) Nicolas Baeyens et al.   JOURNAL OF CLINICAL INVESTIGATION

Biomechanics of vascular mechanosensation and remodeling

(2016) Nicolas Baeyens et al.   MOLECULAR BIOLOGY OF THE CELL

The contribution of branching morphogenesis to kidney development and disease

(2016) Kieran M. Short et al.   Nature Reviews Nephrology

In vivo modulation of endothelial polarization by Apelin receptor signalling

(2016) Hyouk-Bum Kwon et al.   Nature Communications

Synchronization of endothelial Dll4-Notch dynamics switch blood vessels from branching to expansion

(2016) Benedetta Ubezio et al.   eLife

Development and origins of Zebrafish ocular vasculature

(2015) Rivka Kaufman et al.   BMC DEVELOPMENTAL BIOLOGY

The same but different: signaling pathways in control of endothelial cell migration

(2015) Sana S Hasan et al.   CURRENT OPINION IN CELL BIOLOGY

Flow dynamics control the location of sprouting and direct elongation during developmental angiogenesis

(2015) S. Ghaffari et al.   DEVELOPMENT

Venous-derived angioblasts generate organ-specific vessels during zebrafish embryonic development

(2015) G. Hen et al.   DEVELOPMENT

The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development

(2015) Sarah Ivins et al.   DEVELOPMENTAL CELL

The molecular regulation of arteriovenous specification and maintenance

(2015) Jason E. Fish et al.   DEVELOPMENTAL DYNAMICS

Notch signaling regulates venous arterialization during zebrafish fin regeneration

(2015) Yoshiko Kametani et al.   GENES TO CELLS

PTEN mediates Notch-dependent stalk cell arrest in angiogenesis

(2015) Helena Serra et al.   Nature Communications

Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch

(2015) Irene Maria Aspalter et al.   Nature Communications

Endothelial Cell Self-fusion during Vascular Pruning

(2015) Anna Lenard et al.   PLOS BIOLOGY

Dynamic Endothelial Cell Rearrangements Drive Developmental Vessel Regression

(2015) Claudio A. Franco et al.   PLOS BIOLOGY

Mouse models of hereditary hemorrhagic telangiectasia: recent advances and future challenges

(2015) Simon Tual-Chalot et al.   Frontiers in Genetics

Signaling Pathways in the Specification of Arteries and Veins

(2014) Monica Corada et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Distinct Notch signaling outputs pattern the developing arterial system

(2014) A. Quillien et al.   DEVELOPMENT

Cellular and physical mechanisms of branching morphogenesis

(2014) Victor D. Varner et al.   DEVELOPMENT

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Angiogenesis in zebrafish

(2014) Annika Schuermann et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Renal branching morphogenesis: Morphogenetic and signaling mechanisms

(2014) Joshua Blake et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Arteries are formed by vein-derived endothelial tip cells

(2014) Cong Xu et al.   Nature Communications

Endothelial Cell Sensing of Flow Direction

(2013) Chong Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Cell-Cycle State of Stem Cells Determines Cell Fate Propensity

(2013) Siim Pauklin et al.   CELL

Circulating Bmp10 acts through endothelial Alk1 to mediate flow-dependent arterial quiescence

(2013) D. W. Laux et al.   DEVELOPMENT

Notch controls retinal blood vessel maturation and quiescence

(2013) M. Ehling et al.   DEVELOPMENT

Dynamic responses of endothelial cells to changes in blood flow during vascular remodeling of the mouse yolk sac

(2013) Ryan S. Udan et al.   DEVELOPMENT

Arterial and Venous Progenitors of the Major Axial Vessels Originate at Distinct Locations

(2013) Vikram Kohli et al.   DEVELOPMENTAL CELL

ETS Factors Regulate Vegf-Dependent Arterial Specification

(2013) Joshua D. Wythe et al.   DEVELOPMENTAL CELL

The tip cell concept 10 years after: New players tune in for a common theme

(2013) Arndt F. Siekmann et al.   EXPERIMENTAL CELL RESEARCH

Notch as a hub for signaling in angiogenesis

(2013) Rui Benedito et al.   EXPERIMENTAL CELL RESEARCH

Blood Flow Changes Coincide with Cellular Rearrangements during Blood Vessel Pruning in Zebrafish Embryos

(2013) Eva Kochhan et al.   PLoS One

Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development

(2013) N. Sacilotto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VEGF and Notch in Tip and Stalk Cell Selection

(2013) R. Blanco et al.   Cold Spring Harbor Perspectives in Medicine

'In parallel' interconnectivity of the dorsal longitudinal anastomotic vessels requires both VEGF signaling and circulatory flow

(2012) T. Zygmunt et al.   JOURNAL OF CELL SCIENCE

APJ acts as a dual receptor in cardiac hypertrophy

(2012) Maria Cecilia Scimia et al.   NATURE

Branching Morphogenesis: From Cells to Organs and Back

(2012) A. Ochoa-Espinosa et al.   Cold Spring Harbor Perspectives in Biology

Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish

(2012) Qi Chen et al.   PLOS BIOLOGY

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Assembly and patterning of the vascular network of the vertebrate hindbrain

(2011) M. Fujita et al.   DEVELOPMENT

Arterial-venous network formation during brain vascularization involves hemodynamic regulation of chemokine signaling

(2011) J. Bussmann et al.   DEVELOPMENT

Distinct signalling pathways regulate sprouting angiogenesis from the dorsal aorta and the axial vein

(2011) David M. Wiley et al.   NATURE CELL BIOLOGY

Overlapping spectra ofSMAD4mutations in juvenile polyposis (JP) and JP-HHT syndrome

(2010) Carol Gallione et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Role of Delta-like-4/Notch in the Formation and Wiring of the Lymphatic Network in Zebrafish

(2010) Ilse Geudens et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Arteries provide essential guidance cues for lymphatic endothelial cells in the zebrafish trunk

(2010) J. Bussmann et al.   DEVELOPMENT

Pulsatile shear and Gja5 modulate arterial identity and remodeling events during flow-driven arteriogenesis

(2010) I. Buschmann et al.   DEVELOPMENT

Hedgehog signaling induces arterial endothelial cell formation by repressing venous cell fate

(2010) Charles Williams et al.   DEVELOPMENTAL BIOLOGY

MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis

(2010) Stefania Nicoli et al.   NATURE

Coronary arteries form by developmental reprogramming of venous cells

(2010) Kristy Red-Horse et al.   NATURE

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

(2010) Lars Jakobsson et al.   NATURE CELL BIOLOGY

Dynamic Analysis of Vascular Morphogenesis Using Transgenic Quail Embryos

(2010) Yuki Sato et al.   PLoS One

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

VEGFRs and Notch: a dynamic collaboration in vascular patterning: Figure 1

(2009) Lars Jakobsson et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Angiogenesis: A Team Effort Coordinated by Notch

(2009) L.-K. Phng et al.   DEVELOPMENTAL CELL

Hereditary haemorrhagic telangiectasia: a clinical and scientific review

(2009) Fatima S Govani et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Chemokine signaling guides regional patterning of the first embryonic artery

(2009) A. F. Siekmann et al.   GENES & DEVELOPMENT

Modulation of VEGF signalling output by the Notch pathway

(2008) Arndt F. Siekmann et al.   BIOESSAYS

Separating genetic and hemodynamic defects in neuropilin 1 knockout embryos

(2008) E. A. V. Jones et al.   DEVELOPMENT

ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2

(2007) S. O. Park et al.   BLOOD