Dll4 and Notch signalling couples sprouting angiogenesis and artery formation

A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes

(2016) Franz Oswald et al.   NUCLEIC ACIDS RESEARCH

Notch-independent RBPJ controls angiogenesis in the adult heart

(2016) Ramón Díaz-Trelles et al.   Nature Communications

Endothelial Jagged1 Antagonizes Dll4 Regulation of Endothelial Branching and Promotes Vascular Maturation Downstream of Dll4/Notch1

(2015) A.-R. Pedrosa et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Tip cell overtaking occurs as a side effect of sprouting in computational models of angiogenesis

(2015) Sonja E. M. Boas et al.   BMC Systems Biology

Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy

(2015) C. K. Domigan et al.   JOURNAL OF CELL SCIENCE

VEGFR3 does not sustain retinal angiogenesis without VEGFR2

(2015) Georgia Zarkada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic targeting of sprouting angiogenesis using Apln-CreER

(2015) Qiaozhen Liu et al.   Nature Communications

Esm1 Modulates Endothelial Tip Cell Behavior and Vascular Permeability by Enhancing VEGF Bioavailability

(2014) Susana F. Rocha et al.   CIRCULATION RESEARCH

Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice

(2014) C. M. Nielsen et al.   DEVELOPMENT

The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis

(2014) Katie Bentley et al.   NATURE CELL BIOLOGY

Arteries are formed by vein-derived endothelial tip cells

(2014) Cong Xu et al.   Nature Communications

NOTCH Decoys That Selectively Block DLL/NOTCH or JAG/NOTCH Disrupt Angiogenesis by Unique Mechanisms to Inhibit Tumor Growth

(2014) Thaned Kangsamaksin et al.   Cancer Discovery

A bright single-cell resolution live imaging reporter of Notch signaling in the mouse

(2013) Sonja Nowotschin et al.   BMC DEVELOPMENTAL BIOLOGY

Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling

(2013) J. Fan et al.   DEVELOPMENT

Notch controls retinal blood vessel maturation and quiescence

(2013) M. Ehling et al.   DEVELOPMENT

Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis

(2013) Bi-Sen Ding et al.   NATURE

Signal Transduction by Vascular Endothelial Growth Factor Receptors

(2013) S. Koch et al.   Cold Spring Harbor Perspectives in Medicine

Extrinsic Notch Ligand Delta-Like 1 Regulates Tip Cell Selection and Vascular Branching Morphogenesis

(2012) L.C. Napp et al.   CIRCULATION RESEARCH

Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF–VEGFR2 signalling

(2012) Rui Benedito et al.   NATURE

Lineage Tracing Reveals Lgr5+ Stem Cell Activity in Mouse Intestinal Adenomas

(2012) A. G. Schepers et al.   SCIENCE

Angiogenic morphogenesis driven by dynamic and heterogeneous collective endothelial cell movement

(2011) S. Arima et al.   DEVELOPMENT

Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells

(2011) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microarray analysis of retinal endothelial tip cells identifies CXCR4 as a mediator of tip cell morphology and branching

(2010) G. A. Strasser et al.   BLOOD

Identification and functional analysis of endothelial tip cell-enriched genes

(2010) R. del Toro et al.   BLOOD

Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex

(2010) R. Liefke et al.   GENES & DEVELOPMENT

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

(2010) Lars Jakobsson et al.   NATURE CELL BIOLOGY

Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis

(2010) Shiaoching Gong et al.   Nature Protocols

Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice

(2010) Mara E Pitulescu et al.   Nature Protocols

DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries

(2009) I. Sorensen et al.   BLOOD

The Notch Ligands Dll4 and Jagged1 Have Opposing Effects on Angiogenesis

(2009) Rui Benedito et al.   CELL

Tipping the Balance: Robustness of Tip Cell Selection, Migration and Fusion in Angiogenesis

(2009) Katie Bentley et al.   PLoS Computational Biology

Crosstalk Between Vascular Endothelial Growth Factor, Notch, and Transforming Growth Factor-β in Vascular Morphogenesis

(2008) Matthew T. Holderfield et al.   CIRCULATION RESEARCH

Efficient, inducible Cre-recombinase activation in vascular endothelium

(2008) Suzanne Claxton et al.   GENESIS

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment

(2008) Ute Koch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

(2008) Tuomas Tammela et al.   NATURE

Agent-based simulation of notch-mediated tip cell selection in angiogenic sprout initialisation

(2007) Katie Bentley et al.   JOURNAL OF THEORETICAL BIOLOGY

Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells

(2007) Laura S. Harrington et al.   MICROVASCULAR RESEARCH