Intermediate-Dependent Unusual [4+3], [3+2] and Cascade Reactions of 3-Indolylmethanols: Controllable Chemodivergent and Stereoselective Synthesis of Diverse Indole Derivatives

Fluorinated Alcohol-Mediated SN1-Type Reaction of Indolyl Alcohols with Diverse Nucleophiles

(2015) Hao Wen et al.   ADVANCED SYNTHESIS & CATALYSIS

Metal-Free Dehydrogenative Diels-Alder Reactions of 2-Methyl-3-Alkylindoles with Dienophiles: Rapid Access to Tetrahydrocarbazoles, Carbazoles, and Heteroacenes

(2015) Liejin Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Inverse-Electron-Demand Oxa-Diels-Alder Reaction of In Situ Generatedortho-Quinone Methides with 3-Methyl-2-Vinylindoles

(2015) Jia-Jia Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Strategies for the asymmetric functionalization of indoles: an update

(2015) Renato Dalpozzo   CHEMICAL SOCIETY REVIEWS

Formal Asymmetric Organocatalytic [3+2] Cyclization between Enecarbamates and 3-Indolylmethanols: Rapid Access to 3-Aminocyclopenta[b]indoles

(2015) Clément Lebée et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalyst-Dependent Stereodivergent and Regioselective Synthesis of Indole-Fused Heterocycles through Formal Cycloadditions of Indolyl-Allenes

(2015) Liang-Yong Mei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gold(I)-Catalyzed Dearomative Rautenstrauch Rearrangement: Enantioselective Access to Cyclopenta[b]indoles

(2015) Weiwei Zi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Intramolecular C–N Bond Cleavage, 1,4-Migration, sp3 C–H Activation, and Heck Reaction: Four Controllable Diverse Pathways Depending on the Judicious Choice of the Base and Ligand

(2015) Min Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Facile Synthesis of Carbazoles via a Tandem Iodocyclization with 1,2-Alkyl Migration and Aromatization

(2015) Jia Wang et al.   ORGANIC LETTERS

Tf2NH-Catalyzed Amide Synthesis from Vinyl Azides and Alcohols

(2015) Feng-Lian Zhang et al.   ORGANIC LETTERS

Chiral Phosphoric Acid Catalyzed Enantioselective Decarboxylative Alkylation of β-Keto Acids with 3-Hydroxy-3-indolyloxindoles

(2015) Xiao-Dong Tang et al.   ORGANIC LETTERS

Recent Advances in Chiral Phosphoric Acid Catalyzed Asymmetric Reactions for the Synthesis of Enantiopure Indole Derivatives

(2015) Hua Wu et al.   SYNTHESIS-STUTTGART

Enantioselective gold-catalyzed intermolecular [2+2] versus [4+2]-cycloadditions of 3-styrylindoles with N-allenamides: observation of interesting substituent effects

(2015) Yidong Wang et al.   Chemical Science

Friedel–Crafts alkylation of heteroarenes and arenes with indolyl alcohols for construction of 3,3-disubstituted oxindoles

(2015) Xiaoxiao Wang et al.   RSC Advances

CH Functionalization/Asymmetric Michael Addition Cascade Enabled by Relay Catalysis: Metal Carbenoid Used for CC Bond Formation

(2014) Dian-Feng Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric Arylative Dearomatization of 2,3-Disubstituted Indoles Enabled by Tandem Reactions

(2014) Yu-Chen Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic enantioselective and (Z)-selective allylation of 3-indolylmethanol via hydrogen-bond activation

(2014) Yan Liu et al.   CHEMICAL COMMUNICATIONS

Highly diastereo- and enantioselective construction of a spiro[cyclopenta[b]indole-1,3′-oxindole] scaffold via catalytic asymmetric formal [3+2] cycloadditions

(2014) Wei Tan et al.   CHEMICAL COMMUNICATIONS

α-Trifluoromethyl-(indol-3-yl)methanols as trifluoromethylated C31,3-dipoles: [3+2] cycloaddition for the synthesis of 1-(trifluoromethyl)-cyclopenta[b]indole alkaloids

(2014) Jinhuan Dong et al.   CHEMICAL COMMUNICATIONS

Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates

(2014) Dixit Parmar et al.   CHEMICAL REVIEWS

Catalytic Asymmetric Formal [3+3] Cycloaddition of an Azomethine Ylide with 3-Indolylmethanol: Enantioselective Construction of a Six-Membered Piperidine Framework

(2014) Feng Shi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Diastereo- and Enantioselective Construction of a Bispirooxindole Scaffold Containing a Tetrahydro-β-carboline Moiety through an Organocatalytic Asymmetric Cascade Reaction

(2014) Wei Dai et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Asymmetric Cascade Reactions of 7-Vinylindoles: Diastereo- and Enantioselective Synthesis of C7-Functionalized Indoles

(2014) Feng Shi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Anionic Polycyclization Entry to Tricycles Related to Quassinoids and Terpenoids: A Stereocontrolled Total Synthesis of (+)-Cassaine

(2014) Kontham Ravindar et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Asymmetric Aza-ene Reaction of 3-Indolylmethanols with Cyclic Enaminones: Enantioselective Approach to C3-Functionalized Indoles

(2014) Wei Tan et al.   JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Arylation of 3-Indolylmethanols via Chemo- and Regiospecific C6-Functionalization of Indoles

(2014) Lu-Jia Zhou et al.   JOURNAL OF ORGANIC CHEMISTRY

Intramolecular [3 + 2] Cyclocondensations of Alkenes with Indolidenes and Indolidenium Cations

(2014) Ken S. Feldman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic functionalization of tertiary alcohols to fully substituted carbon centres

(2014) Long Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The Direct Asymmetric Alkylation of α-Amino Aldehydes with 3-Indolylmethanols by Enamine Catalysis

(2014) Zhi-Lei Guo et al.   ORGANIC LETTERS

An Approach to Cyclohepta[b]indoles through an Allenamide (4 + 3) Cycloaddition–Grignard Cyclization–Chugaev Elimination Sequence

(2014) Shuzhong He et al.   ORGANIC LETTERS

Enantioselective Synthesis of Triarylmethanes by Chiral Imidodiphosphoric Acids Catalyzed Friedel–Crafts Reactions

(2014) Ming-Hua Zhuo et al.   ORGANIC LETTERS

Imine and iminium precursors as versatile intermediates in enantioselective organocatalysis

(2014) Antti O. Kataja et al.   TETRAHEDRON

Catalytic asymmetric direct α-alkylation of amino esters by aldehydes via imine activation

(2014) Biao Xu et al.   Chemical Science

Highly efficient [3 + 2] reaction of 3-vinylindoles with 3-indolylmethanols by Brønsted-acid catalysis

(2014) Cheng Zhang et al.   RSC Advances

Chiral Brønsted Acid Catalyzed Stereoselective [3+3] Cycloaddition Reaction of Azomethine Ylide to Vinylimine Intermediates: Constructing Fully Functionalized Chiral Tetrahydro-β-Carboline

(2013) Jianzhou Huang et al.   ACTA CHIMICA SINICA

Rhodium- and Platinum-Catalyzed [4+3] Cycloaddition with Concomitant Indole Annulation: Synthesis of Cyclohepta[b]indoles

(2013) Dongxu Shu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Organocatalytic Construction of Hexahydropyrroloindole by Means of α-Alkylation of Aldehydes Leading to the Total Synthesis of (+)-Gliocladin C

(2013) Jin Song et al.   CHEMISTRY-A EUROPEAN JOURNAL

Regio- and Stereoselective[4+3] Cycloaddition Towards Fused 5,7,6-Tricyclic Skeletons

(2013) Wanchun Gong et al.   Chemistry-An Asian Journal

A Combined Theoretical and Experimental Investigation into the Highly Stereoselective Migration of Spiroindolenines

(2013) Chao Zheng et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Benzocyclohepta[b]indoles by Lewis Acid Catalyzed Annulation of Two 3-(1H-Isochromen-1-yl)-1H-indoles

(2013) Ye-Xiang Xie et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Highly Enantioselective Cyclopentannulation of Indoles with Donor–Acceptor Cyclopropanes

(2013) Hu Xiong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Functionalization of Indoles and Pyrroles via an in Situ-Formed Spiro Intermediate

(2013) Chun-Xiang Zhuo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Cyclohepta[b]indoles: Gram-Scale Synthesis of (S)-SIRT1-Inhibitor IV

(2013) Philipp J. Gritsch et al.   ORGANIC LETTERS

One-Pot Asymmetric Synthesis of Seven-Membered Carbocycles Cyclohepta[b]indoles via a Sequential Organocatalytic Michael/Double Friedel–Crafts Alkylation Reaction

(2013) Nitin S. Dange et al.   ORGANIC LETTERS

Acid-promoted Cascade Cyclization to Produce Fused-polycyclic Indole Derivatives

(2013) Takuya Yokosaka et al.   ORGANIC LETTERS

Construction of Cyclohepta[b]indoles via Platinum-Catalyzed Intermolecular Formal [4+3]-Cycloaddition Reaction of α,β-Unsaturated Carbene Complex Intermediates with Siloxydienes

(2013) Nobuharu Iwasawa et al.   SYNLETT

Nazarov reagents and their use in organic synthesis

(2013) Gérard Audran et al.   TETRAHEDRON

Iodine-Catalyzed Cascade Formal [3 + 3] Cycloaddition Reaction of Indolyl Alcohol Derivatives with Enaminones: Constructions of Functionalized Spirodihydrocarbolines

(2013) Wen-Juan Hao et al.   ACS Catalysis

Enantioselective Synthesis of Spiro Cyclopentane-1,3′-indoles and 2,3,4,9-Tetrahydro-1H-carbazoles by Iridium-Catalyzed Allylic Dearomatization and Stereospecific Migration

(2012) Qing-Feng Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gallium(III)-Catalyzed Three-Component (4+3) Cycloaddition Reactions

(2012) Xinping Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Construction of Pyrroloindolines Catalyzed by Chiral Phosphoric Acids: Total Synthesis of (−)-Debromoflustramine B

(2012) Zuhui Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Direct Asymmetric α Alkylation of Ketones by Brønsted Acid Catalysis

(2012) Liu Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An acid-promoted novel skeletal rearrangement initiated by intramolecular ipso-Friedel–Crafts-type addition to 3-alkylidene indolenium cations

(2012) Takuya Yokosaka et al.   CHEMICAL COMMUNICATIONS

The acid free asymmetric intermolecular α-alkylation of aldehydes in fluorinated alcohols

(2012) Jian Xiao et al.   CHEMICAL COMMUNICATIONS

Phosphine-Catalyzed Domino Reaction for the Synthesis of Conjugated 2,3-Dihydrofurans from Allenoates and Nazarov Reagents

(2012) Peizhong Xie et al.   Chemistry-An Asian Journal

Iridium-Catalyzed Enantioselective Allylic Vinylation

(2012) James Y. Hamilton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Three-Component Domino Reactions for Selective Formation of Indeno[1,2-b]indole Derivatives

(2012) Bo Jiang et al.   ORGANIC LETTERS

Electronic Effect Directed Au(I)-Catalyzed Cyclic C2–H Bond Functionalization of 3-Allenylindoles

(2012) Bo Chen et al.   ORGANIC LETTERS

Merging Organocatalysis with Transition Metal Catalysis: Highly Stereoselective α-Alkylation of Aldehydes

(2012) Jian Xiao   ORGANIC LETTERS

A Catalytic Asymmetric Isatin-Involved Povarov Reaction: Diastereo- and Enantioselective Construction of Spiro[indolin-3,2′-quinoline] Scaffold

(2012) Feng Shi et al.   ORGANIC LETTERS

Brønsted-Acid-Catalyzed Asymmetric Multicomponent Reactions for the Facile Synthesis of Highly Enantioenriched Structurally Diverse Nitrogenous Heterocycles

(2011) Jie Yu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Multistep One-Pot Synthesis of Enantioenriched Polysubstituted Cyclopenta[b]indoles

(2011) Biao Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Core-Structure-Oriented Asymmetric Organocatalytic Substitution of 3-Hydroxyoxindoles: Application in the Enantioselective Total Synthesis of (+)-Folicanthine

(2011) Chang Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Intermolecular Alkylation of Aldehydes with Alcohols by Cooperative Catalysis of Diarylprolinol Silyl Ether with Brønsted Acid

(2011) Jian Xiao et al.   Chemistry-An Asian Journal

Indole Alkaloids and Quassinoids from the Stems ofBrucea mollis

(2011) Hui Chen et al.   JOURNAL OF NATURAL PRODUCTS

Dehydration triggered asymmetric hydrogenation of 3-(α-hydroxyalkyl)indoles

(2011) Duo-Sheng Wang et al.   Chemical Science

Lewis Acid Catalyzed Intramolecular Direct Ene Reaction of Indoles

(2010) Bo Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Brønsted Acid Catalyzed Pinacol Rearrangement

(2010) Tao Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic strategies for the asymmetric functionalization of indoles

(2010) Giuseppe Bartoli et al.   CHEMICAL SOCIETY REVIEWS

Gold-Catalyzed Intramolecular Indole/Alkyne Cyclization Cascades through a Heterolytic Fragmentation: 1,5-Indole Migration and Allenylation

(2010) Guijie Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Construction of Spiroindolenines by Ir-Catalyzed Allylic Alkylation Reactions

(2010) Qing-Feng Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Platinum(II)-Catalyzed Generation and [3+2] Cycloaddition Reaction of α,β-Unsaturated Carbene Complex Intermediates for the Preparation of Polycyclic Compounds

(2010) Kodai Saito et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Simple indole alkaloids and those with a nonrearranged monoterpenoid unit

(2010) Minoru Ishikura et al.   NATURAL PRODUCT REPORTS

Versatile Strategy to Access Tricycles Related to Quassinoids and Triterpenes

(2010) Pierre-Yves Caron et al.   ORGANIC LETTERS

Organocatalytic Asymmetric Formal [4 + 2] Cycloaddition for the Synthesis of Spiro[4-cyclohexanone-1,3′-oxindoline] Derivatives in High Optical Purity

(2010) Qiang Wei et al.   ORGANIC LETTERS

Chiral Phosphoric Acids as Versatile Catalysts for Enantioselective Transformations

(2010) Masahiro Terada   SYNTHESIS-STUTTGART

Organocatalytic Asymmetric Alkylation of Aldehydes by SN1-Type Reaction of Alcohols

(2009) Pier Giorgio Cozzi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting Structural and Stereochemical Complexity by Organocascade Catalysis: Construction of Spirocyclic Oxindoles Having Multiple Stereocenters

(2009) Giorgio Bencivenni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors

(2009) Tjeerd Barf et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Chiral Brønsted acid catalyzed Friedel–Crafts alkylation reactions

(2009) Shu-Li You et al.   CHEMICAL SOCIETY REVIEWS

Divergent Pathways in the Biosynthesis of Bisindole Natural Products

(2009) Katherine S. Ryan et al.   CHEMISTRY & BIOLOGY

Enantioselective Synthesis of Fluorene Derivatives by Chiral Phosphoric Acid Catalyzed Tandem Double Friedel-Crafts Reaction

(2009) Feng-Lai Sun et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Synthetic Approach to Ervatamine-Silicine Alkaloids. Enantioselective Total Synthesis of (−)-16-Episilicine†

(2009) Mercedes Amat et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of 3-substituted indoles via reactive alkylideneindolenine intermediates

(2009) Alessandro Palmieri et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Enantioselective Alkylation Reaction of Enamides by Brønsted-Acid Catalysis

(2009) Qi-Xiang Guo et al.   ORGANIC LETTERS

Stereoselective Double Friedel−Crafts Alkylation of Indoles with Divinyl Ketones

(2009) Andrew C. Silvanus et al.   ORGANIC LETTERS

Organocatalytic Asymmetric Formal [3+3] Cycloaddition Reactions of α,β-Unsaturated Aldehydes with Nazarov Reagents

(2008) Ming-Kui Zhu et al.   ADVANCED SYNTHESIS & CATALYSIS

Binaphthol-derived phosphoric acid as a versatile catalyst for enantioselective carbon–carbon bond forming reactions

(2008) Masahiro Terada   CHEMICAL COMMUNICATIONS