Stereocontrolled Construction of 3,4-Dihydrocoumarin Scaffolds with a Quaternary Amino Acid MoietyviaChiral Squaramide-Catalyzed Cascade Michael Addition/Lactonization Reaction

Bifunctional Amine-Squaramides: Powerful Hydrogen-Bonding Organocatalysts for Asymmetric Domino/Cascade Reactions

(2015) Pankaj Chauhan et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic enantioselective formal arylation of azlactones using quinones as the aromatic partner

(2015) Guofeng Li et al.   CHEMICAL COMMUNICATIONS

Enantioselective synthesis of dihydrocoumarin derivatives by chiral scandium(iii)-complex catalyzed inverse-electron-demand hetero-Diels–Alder reaction

(2015) Haipeng Hu et al.   CHEMICAL COMMUNICATIONS

N-Heterocyclic carbene-catalyzed enantioselective annulations: a dual activation strategy for a formal [4+2] addition for dihydrocoumarins

(2015) Anna Lee et al.   CHEMICAL COMMUNICATIONS

Organocatalytic one-pot 1,4-/1,6-/1,2-addition sequence for the stereocontrolled formation of six consecutive stereocenters

(2015) Pankaj Chauhan et al.   CHEMICAL COMMUNICATIONS

Catalytic Asymmetric Addition of Meldrum’s Acid, Malononitrile, and 1,3-Dicarbonyls toortho-Quinone Methides Generated In Situ Under Basic Conditions

(2015) Lorenzo Caruana et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chemoselective N-Heterocyclic Carbene-Catalyzed Cascade of Enals with Nitroalkenes

(2015) Zijun Wu et al.   ORGANIC LETTERS

Asymmetric Multicomponent Sulfa-Michael/Mannich Cascade Reaction: Synthetic Access to 1,2-Diamino-3-Organosulfur Compounds and 2-Nitro Allylic Amines

(2015) Wenduan Hou et al.   ORGANIC LETTERS

Highly Enantioselective Cascade Reaction Catalyzed by Squaramides: the Synthesis of CF3-Containing Chromanes

(2015) Yuanyuan Zhu et al.   ORGANIC LETTERS

Bifunctional Squaramide Catalysts with the Same Absolute Chirality for the Diastereodivergent Access to Densely Functionalised Cyclohexanes through Enantioselective Domino Reactions. Synthesis and Mechanistic Studies

(2014) Jose I. Martínez et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric Tamura Cycloadditions

(2014) Francesco Manoni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antioxidant and antitumor activities of 4-arylcoumarins and 4-aryl-3,4-dihydrocoumarins

(2014) Keyun Zhang et al.   BIOCHIMIE

Asymmetric synthesis of functionalized cyclohexanes bearing five stereocenters via a one-pot organocatalytic Michael–Michael–1,2-addition sequence

(2014) Pankaj Chauhan et al.   CHEMICAL COMMUNICATIONS

Asymmetric Synthesis of Tetrahydropyridines via an Organocatalytic One-Pot Multicomponent Michael/Aza-Henry/Cyclization Triple Domino Reaction

(2014) Marcus Blümel et al.   ORGANIC LETTERS

Straightforward Enantioselective Access to γ-Butyrolactones Bearing an All-Carbon β-Quaternary Stereocenter

(2014) Sara Meninno et al.   ORGANIC LETTERS

Asymmetric Synthesis of Trisubstituted Oxazolidinones by the Thiourea-Catalyzed Aldol Reaction of 2-Isocyanatomalonate Diester

(2014) Shota Sakamoto et al.   ORGANIC LETTERS

Asymmetric Synthesis of Highly Functionalized Tetrahydropyrans via a One-Pot Organocatalytic Michael/Henry/Ketalization Sequence

(2014) Robert Hahn et al.   ORGANIC LETTERS

Organocatalytic Route to Dihydrocoumarins and Dihydroquinolinones in All Stereochemical Configurations

(2014) Oliver D. Engl et al.   ORGANIC LETTERS

An Organocatalytic Michael–Michael Cascade for the Enantioselective Construction of Spirocyclopentane Bioxindoles: Control of Four Contiguous Stereocenters

(2014) Wangsheng Sun et al.   ORGANIC LETTERS

Kinetic resolution of 4-substituted-3,4-dihydrocoumarins via Pd-catalyzed asymmetric allylic alkylation reaction: enantioselective synthesis of trans-3,4-disubstituted-3,4-dihydrocoumarins

(2014) Xiao-Hui Li et al.   Organic Chemistry Frontiers

Asymmetric Organocatalytic Cascade Michael/Hemiketalization/Retro-Aldol Reaction of 2-[(E)-2-Nitrovinyl]phenols with 2,4-Dioxo-4-arylbutanoates: A Convenient Access to Chiral α-Keto Esters

(2013) Yunting Liu et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Optically Active 2H-Thiopyrano[2,3-b]quinolines with Three Contiguous Stereocentersviaan Organocatalytic Asymmetric Tandem Michael-Henry Reaction

(2013) Lulu Wu et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Synthesis of Functionalized Tetrahydronaphthalenesviaan Organocatalytic Nitroalkane-Michael/Henry Domino Reaction

(2013) Dieter Enders et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric domino synthesis of indanes bearing four contiguous stereocentres catalyzed by sub-mol% loadings of a squaramide in minutes

(2013) Charles C. J. Loh et al.   CHEMICAL COMMUNICATIONS

Cinchona-based squaramide-catalysed cascade aza-Michael–Michael addition: enantioselective construction of functionalized spirooxindole tetrahydroquinolines

(2013) Wen Yang et al.   CHEMICAL COMMUNICATIONS

Asymmetric synthesis of trans-dihydroarylfurans in a Friedel–Crafts/substitution domino reaction under squaramide catalysis

(2013) Carlos Jarava-Barrera et al.   CHEMICAL COMMUNICATIONS

Planar chiral [2.2]paracyclophane-based bis(thiourea) catalyst: application to asymmetric Henry reaction

(2013) Shinji Kitagaki et al.   CHEMICAL COMMUNICATIONS

Direct asymmetric aldol addition–isomerization of α,β-unsaturated γ-butyrolactam with aryl α-ketoesters: synthesis of MBH-type products

(2013) Jinlong Zhang et al.   CHEMICAL COMMUNICATIONS

Enantioselective Organocatalytic Domino Michael/Aldol Reactions: An Efficient Procedure for the Stereocontrolled Construction of 2H-Thiopyrano[2,3-b]quinoline Scaffolds

(2013) Lulu Wu et al.   Chemistry-An Asian Journal

Chiral Tertiary Amine Thiourea-Catalyzed Asymmetric Inverse-Electron-Demand Diels–Alder Reaction of Chromone Heterodienes Using 3-Vinylindoles as Dienophiles

(2013) Zhijie Mao et al.   JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Domino Reaction of Cyanosulfones: Access to Complex Cyclohexane Systems with Quaternary Carbon Centers

(2013) Sundaram Rajkumar et al.   ORGANIC LETTERS

Organocatalytic oxa/aza-Michael–Michael Cascade Strategy for the Construction of Spiro [Chroman/Tetrahydroquinoline-3,3′-oxindole] Scaffolds

(2013) Haibin Mao et al.   ORGANIC LETTERS

Squaramide–Tertiary Amine Catalyzed Asymmetric Cascade Sulfa-Michael/Michael Addition via Dynamic Kinetic Resolution: Access to Highly Functionalized Chromans with Three Contiguous Stereocenters

(2013) Wen Yang et al.   ORGANIC LETTERS

Phosphine-Catalyzed [3 + 2] Cycloaddition of 4,4-Dicyano-2-methylenebut-3-enoates with Benzyl Buta-2,3-dienoate and Penta-3,4-dien-2-one

(2013) Xiao-Nan Zhang et al.   ACS Catalysis

Synthesis and biological evaluation of α-methylidene-δ-lactones with 3,4-dihydrocoumarin skeleton

(2012) Jakub Modranka et al.   BIOORGANIC & MEDICINAL CHEMISTRY

3-Bromooxindoles as nucleophiles in asymmetric organocatalytic Mannich reactions with N-Ts-imines

(2012) Jianhao Li et al.   CHEMICAL COMMUNICATIONS

Applications of asymmetric organocatalysis in medicinal chemistry

(2012) José Alemán et al.   CHEMICAL SOCIETY REVIEWS

Synthesis and antimicrobial activities of 4-aryl-3,4-dihydrocoumarins and 4-arylcoumarins

(2012) Jie Sun et al.   CHEMISTRY OF NATURAL COMPOUNDS

Catalytic Asymmetric Direct Vinylogous Michael Addition of Deconjugated Butenolides to Maleimides for the Construction of Quaternary Stereogenic Centers

(2012) Madhu Sudan Manna et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Asymmetric Michael Addition/Cyclization of Isothiocyanato Oxindoles: Highly Efficient and Versatile Approach for the Synthesis of 3,2′-Pyrrolidinyl Mono- and Bi-spirooxindole Frameworks

(2012) Yi-Ming Cao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Synthesis of trans-Dihydrobenzofurans via Primary Amine-Thiourea Organocatalyzed Intramolecular Michael Addition

(2012) Aidang Lu et al.   JOURNAL OF ORGANIC CHEMISTRY

Deracemization of α-Aryl Hydrocoumarins via Catalytic Asymmetric Protonation of Ketene Dithioacetals

(2012) Ji-Woong Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bioinspired organocatalytic asymmetric reactions

(2012) Luca Bernardi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

N-heterocyclic carbene-catalyzed [4 + 2] cycloaddition of ketenes and 3-aroylcoumarins: highly enantioselective synthesis of dihydrocoumarin-fused dihydropyranones

(2012) Teng-Yue Jian et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Formation of Substituted 3,4-Dihydrocoumarins by a Multicatalytic One-Pot Process

(2012) Christian Borch Jacobsen et al.   ORGANIC LETTERS

Asymmetric organocatalytic cascade Michael/hemiketalization/retro-Henry reaction of β,γ-unsaturated ketoesters with α-nitroketones

(2011) Yaojun Gao et al.   CHEMICAL COMMUNICATIONS

Catalytic asymmetric conjugate addition of Grignard reagents to coumarins—synthesis of versatile chiral building blocks

(2011) Johannes F. Teichert et al.   CHEMICAL COMMUNICATIONS

Expeditious Assembly of a 2-Amino-4H-chromene Skeleton by Using an Enantioselective Mannich Intramolecular Ring Cyclization-Tautomerization Cascade Sequence

(2011) Qiao Ren et al.   CHEMISTRY-A EUROPEAN JOURNAL

Squaramides: Bridging from Molecular Recognition to Bifunctional Organocatalysis

(2011) José Alemán et al.   CHEMISTRY-A EUROPEAN JOURNAL

Oxazolones in Organocatalysis, New Tricks for an Old Reagent

(2011) Andrea-Nekane R. Alba et al.   Chemistry-An Asian Journal

Thiourea-Catalyzed Asymmetric Mannich-Type Reactions

(2011) Bo Han et al.   CURRENT ORGANIC CHEMISTRY

Rhodium-catalysed enantioselective synthesis of 4-arylchroman-2-ones

(2011) Joseph C. Allen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Catalytic Asymmetric Conjugate Allylation of Coumarins

(2011) Yulong Kuang et al.   ORGANIC LETTERS

Asymmetric Synthesis of 3,4-Dihydrocoumarin Motif with an All-Carbon Quaternary Stereocenterviaa Michael–Acetalization Sequence with Bifunctional Amine-thiourea Organocatalysts

(2011) Bor-Cherng Hong et al.   ORGANIC LETTERS

Asymmetric organocatalytic reactions by bifunctional amine-thioureas

(2011) Woon-Yew Siau et al.   Catalysis Science & Technology

Copper-Catalyzed Asymmetric 1,4-Hydroboration of Coumarins with Pinacolborane: Asymmetric Synthesis of Dihydrocoumarins

(2010) Hyohyun Kim et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Synthesis of cis-3,4-Disubstituted Chromans and Dihydrocoumarins via an Organocatalytic Michael Addition/ Hemiacetalization Reaction

(2010) Dieter Enders et al.   ADVANCED SYNTHESIS & CATALYSIS

Development of Chiral Thiourea Catalysts and Its Application to Asymmetric Catalytic Reactions

(2010) Yoshiji Takemoto   CHEMICAL & PHARMACEUTICAL BULLETIN

Enantioselective heterocyclic synthesis of spiro chromanone–thiochroman complexes catalyzed by a bifunctional indane catalyst

(2010) Yaojun Gao et al.   CHEMICAL COMMUNICATIONS

Enantioselective Synthesis of Densely Functionalized Pyranochromenes via an Unpredictable Cascade Michael-Oxa-Michael-Tautomerization Sequence

(2010) Qiao Ren et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Synthesis of Coumarins Catalyzed by a Bifunctional Amine-Thiourea Catalyst

(2010) Yaojun Gao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Asymmetric Tandem Michael Addition−Hemiacetalization: A Route to Chiral Dihydrocoumarins, Chromanes, and 4H-Chromenes

(2010) Dengfu Lu et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Synthesis of DihydrocoumarinsviaN-Heterocyclic Carbene-Catalyzed Cycloaddition of Ketenes ando-Quinone Methides

(2009) Hui Lv et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalysis—after the gold rush

(2009) Søren Bertelsen et al.   CHEMICAL SOCIETY REVIEWS

Organocatalytic Domino Reactions

(2009) Andrea-Nekane Alba et al.   CURRENT ORGANIC CHEMISTRY

High Pressure Diels−Alder Approach to Hydroxy-Substituted 6a-Cyano-tetrahydro-6H-benzo[c]chromen-6-ones: A Route to Δ6-Cis-Cannabidiol

(2009) Eleonora Ballerini et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Conjugate Reductions of Coumarins. A New Route to Tolterodine and Related Coumarin Derivatives

(2009) Brian D. Gallagher et al.   ORGANIC LETTERS

Control of Chemoselectivity by Counteranions of Cationic Palladium Complexes: A Convenient Enantioselective Synthesis of Dihydrocoumarins

(2009) Xiuling Han et al.   ORGANIC LETTERS

Asymmetric Aminocatalysis-Gold Rush in Organic Chemistry

(2008) Paolo Melchiorre et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Organocatalysis: From Infancy to Adolescence

(2008) Alessandro Dondoni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The advent and development of organocatalysis

(2008) David W. C. MacMillan   NATURE

Asymmetric Cycloadditions ofo-Quinone Methides Employing Chiral Ammonium Fluoride Precatalysts

(2008) Ethan Alden-Danforth et al.   ORGANIC LETTERS