Journal
ORGANIC LETTERS
Volume 17, Issue 14, Pages 3588-3591Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b01692
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Funding
- Thousand Plan Youth program
- Bayer Investigator Fellowship
- Tsinghua University
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An unprecedented N-heterocyclic carbene catalyzed chemoselective and enantioselective cascade reaction of enals with nitroalkenes has been developed. A wide range of enantioenriched dihydrocoumarins has been prepared, and the reaction goes through an enolate intermediate generated under a catalytic process.
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