Neutron scattering in the biological sciences: progress and prospects

Dynamic Neutron Scattering by Biological Systems

(2018) Jeremy C. Smith et al.   Annual Review of Biophysics

Neutron Crystallography Detects Differences in Protein Dynamics: Structure of the PKG II Cyclic Nucleotide Binding Domain in Complex with an Activator

(2018) Oksana Gerlits et al.   BIOCHEMISTRY

Structural investigation of cellobiose dehydrogenase IIA: Insights from small angle scattering into intra- and intermolecular electron transfer mechanisms

(2018) Annette M. Bodenheimer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Interleaflet Coupling in Asymmetric Membranes: Protocols and Revelations

(2018) Milka Doktorova et al.   BIOPHYSICAL JOURNAL

Solution Structure of an Intramembrane Aspartyl Protease via Small Angle Neutron Scattering

(2018) Swe-Htet Naing et al.   BIOPHYSICAL JOURNAL

Intrinsic Curvature-Mediated Transbilayer Coupling in Asymmetric Lipid Vesicles

(2018) Barbara Eicher et al.   BIOPHYSICAL JOURNAL

Perdeuteration of cholesterol for neutron scattering applications using recombinant Pichia pastoris

(2018) Martine Moulin et al.   CHEMISTRY AND PHYSICS OF LIPIDS

The impact of deuteration on natural and synthetic lipids: A neutron diffraction study

(2018) Alessandra Luchini et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Clogging in staked-in needle pre-filled syringes (SIN-PFS): Influence of water vapor transmission through the needle shield

(2018) M. De Bardi et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design

(2018) Francesco Manzoni et al.   JOURNAL OF MEDICINAL CHEMISTRY

A low-pressure GO nanofiltration membrane crosslinked via ethylenediamine

(2018) Na Meng et al.   JOURNAL OF MEMBRANE SCIENCE

Elucidating the Solvent Effect on the Switch of the Helicity of Poly(quinoxaline-2,3-diyl)s: A Conformational Analysis by Small-Angle Neutron Scattering

(2018) Yuuya Nagata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unlocking high spatial resolution in neutron imaging through an add-on fibre optics taper

(2018) M. Morgano et al.   OPTICS EXPRESS

High-pressure cell for simultaneous dielectric and neutron spectroscopy

(2018) Alejandro Sanz et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

"To Be or Not to Be" Protonated: Atomic Details of Human Carbonic Anhydrase-Clinical Drug Complexes by Neutron Crystallography and Simulation

(2018) Andrey Kovalevsky et al.   STRUCTURE

Substrate Binding Induces Conformational Changes in a Class A β-lactamase That Prime It for Catalysis

(2018) Patricia S. Langan et al.   ACS Catalysis

Microscopic diffusion processes measured in living planarians

(2018) Eugene Mamontov   Scientific Reports

IMAGINE: neutrons reveal enzyme chemistry

(2018) Gabriela C. Schröder et al.   Acta Crystallographica Section D-Structural Biology

Instrument and shielding design of a neutron diffractometer at J-PARC for protein crystallography covering crystals with large unit-cell volume

(2018) Kazuo Kurihara et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad

(2018) Prashasti Kumar et al.   Science Advances

Franck–Condon picture of incoherent neutron scattering

(2018) Gerald R. Kneller   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The rise of neutron cryo-crystallography

(2018) Hanna Kwon et al.   Acta Crystallographica Section D-Structural Biology

Small-Angle Neutron Scattering Reveals Energy Landscape for Rhodopsin Photoactivation

(2018) Suchithranga M. D. C. Perera et al.   Journal of Physical Chemistry Letters

Invisible detergents for structure determination of membrane proteins by small-angle neutron scattering

(2017) Søren Roi Midtgaard et al.   FEBS Journal

The cytosolic domain of T-cell receptor ζ associates with membranes in a dynamic equilibrium and deeply penetrates the bilayer

(2017) Kerstin Zimmermann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influence of the membrane environment on cholesterol transfer

(2017) Jeffrey Michael Breidigan et al.   JOURNAL OF LIPID RESEARCH

Room Temperature Neutron Crystallography of Drug Resistant HIV-1 Protease Uncovers Limitations of X-ray Structural Analysis at 100 K

(2017) Oksana Gerlits et al.   JOURNAL OF MEDICINAL CHEMISTRY

Probing Elastic and Viscous Properties of Phospholipid Bilayers Using Neutron Spin Echo Spectroscopy

(2017) Michihiro Nagao et al.   Journal of Physical Chemistry Letters

In Vivo Protein Dynamics on the Nanometer Length Scale and Nanosecond Time Scale

(2017) Divina B. Anunciado et al.   Journal of Physical Chemistry Letters

Designing Mixed Detergent Micelles for Uniform Neutron Contrast

(2017) Ryan C. Oliver et al.   Journal of Physical Chemistry Letters

Reconciling Differences between Lipid Transfer in Free-Standing and Solid Supported Membranes: A Time-Resolved Small-Angle Neutron Scattering Study

(2017) Benny Wah et al.   LANGMUIR

Influence of cosolvents, self-crowding, temperature and pressure on the sub-nanosecond dynamics and folding stability of lysozyme

(2017) S. R. Al-Ayoubi et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Influence of particle size and dielectric environment on the dispersion behaviour and surface plasmon in nickel nanoparticles

(2017) Vikash Sharma et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Rhizodeposition under drought is controlled by root growth rate and rhizosphere water content

(2017) Maire Holz et al.   PLANT AND SOIL

Quantifying root water extraction after drought recovery using sub-mm in situ empirical data

(2017) Indu Dhiman et al.   PLANT AND SOIL

Multi-scale characterisation of deuterated cellulose composite hydrogels reveals evidence for different interaction mechanisms with arabinoxylan, mixed-linkage glucan and xyloglucan

(2017) Marta Martínez-Sanz et al.   POLYMER

The role of momentum transfer during incoherent neutron scattering is explained by the energy landscape model

(2017) Hans Frauenfelder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural features and lipid binding domain of tubulin on biomimetic mitochondrial membranes

(2017) David P. Hoogerheide et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutron crystallographic studies of T4 lysozyme at cryogenic temperature

(2017) Le Li et al.   PROTEIN SCIENCE

Neutron structure of the T26H mutant of T4 phage lysozyme provides insight into the catalytic activity of the mutant enzyme and how it differs from that of wild type

(2017) Takeshi Hiromoto et al.   PROTEIN SCIENCE

Protein-peptide association kinetics beyond the seconds timescale from atomistic simulations

(2017) Fabian Paul et al.   Nature Communications

Direct visualization of critical hydrogen atoms in a pyridoxal 5′-phosphate enzyme

(2017) Steven Dajnowicz et al.   Nature Communications

Cryo-EM structure of haemoglobin at 3.2 Å determined with the Volta phase plate

(2017) Maryam Khoshouei et al.   Nature Communications

Molecular Mechanism of Enzymatic Chlorite Detoxification: Insights from Structural and Kinetic Studies

(2017) Irene Schaffner et al.   ACS Catalysis

Structural characterization of membrane-bound human immunodeficiency virus-1 Gag matrix with neutron reflectometry

(2017) Rebecca Eells et al.   Biointerphases

Neutron crystallography of photoactive yellow protein reveals unusual protonation state of Arg52 in the crystal

(2017) Kento Yonezawa et al.   Scientific Reports

An extended N-H bond, driven by a conserved second-order interaction, orients the flavin N5 orbital in cholesterol oxidase

(2017) Emily Golden et al.   Scientific Reports

Dynamics of water bound to crystalline cellulose

(2017) Hugh O’Neill et al.   Scientific Reports

The in vivo structure of biological membranes and evidence for lipid domains

(2017) Jonathan D. Nickels et al.   PLOS BIOLOGY

Preliminary neutron diffraction analysis of challenging human manganese superoxide dismutase crystals

(2017) Jahaun Azadmanesh et al.   Acta Crystallographica Section F-Structural Biology Communications

Ewald: an extended wide-angle Laue diffractometer for the second target station of the Spallation Neutron Source

(2017) Leighton Coates et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Back-exchange of deuterium in neutron crystallography: characterization by IR spectroscopy

(2017) Ai Woon Yee et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Time-resolved neutron scattering provides new insight into protein substrate processing by a AAA+ unfoldase

(2017) Ziad Ibrahim et al.   Scientific Reports

Capturing 3D Water Flow in Rooted Soil by Ultra-fast Neutron Tomography

(2017) Christian Tötzke et al.   Scientific Reports

Long-Range Electrostatics-Induced Two-Proton Transfer Captured by Neutron Crystallography in an Enzyme Catalytic Site

(2016) Oksana Gerlits et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Neutron protein crystallography: A complementary tool for locating hydrogens in proteins

(2016) William B. O'Dell et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

HIV-1 matrix-31 membrane binding peptide interacts differently with membranes containing PS vs . PI(4,5)P 2

(2016) Lauren O'Neil et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Ancestral protein reconstruction: techniques and applications

(2016) Rainer Merkl et al.   BIOLOGICAL CHEMISTRY

Characterising protein/detergent complexes by triple-detection size-exclusion chromatography

(2016) Katharina Gimpl et al.   BIOLOGICAL PROCEDURES ONLINE

Comparative genomics and transcriptomics of Pichia pastoris

(2016) Kerry R. Love et al.   BMC GENOMICS

Bio-deuterated cellulose thin films for enhanced contrast in neutron reflectometry

(2016) Vikram Singh Raghuwanshi et al.   CELLULOSE

Semiempirical Quantum Mechanical Methods for Noncovalent Interactions for Chemical and Biochemical Applications

(2016) Anders S. Christensen et al.   CHEMICAL REVIEWS

Matchout deuterium labelling of proteins for small-angle neutron scattering studies using prokaryotic and eukaryotic expression systems and high cell-density cultures

(2016) O. Dunne et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Cosolvent pretreatment in cellulosic biofuel production: effect of tetrahydrofuran-water on lignin structure and dynamics

(2016) Micholas Dean Smith et al.   GREEN CHEMISTRY

Glutaraldehyde-crosslinking for improved copper absorption selectivity and chemical stability of polyethyleneimine coatings

(2016) Johan B. Lindén et al.   JOURNAL OF APPLIED POLYMER SCIENCE

Small-angle neutron scattering and molecular dynamics structural study of gelling DNA nanostars

(2016) J. Fernandez-Castanon et al.   JOURNAL OF CHEMICAL PHYSICS

Communication: A multiscale Bayesian inference approach to analyzing subdiffusion in particle trajectories

(2016) Konrad Hinsen et al.   JOURNAL OF CHEMICAL PHYSICS

Evolution and characterization of a new reversibly photoswitching chromogenic protein, Dathail

(2016) Patricia S. Langan et al.   JOURNAL OF MOLECULAR BIOLOGY

Enhanced Dynamics of Hydrated tRNA on Nanodiamond Surfaces: A Combined Neutron Scattering and MD Simulation Study

(2016) Gurpreet K. Dhindsa et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Quasi-elastic Neutron Scattering Reveals Ligand-Induced Protein Dynamics of a G-Protein-Coupled Receptor

(2016) Utsab R. Shrestha et al.   Journal of Physical Chemistry Letters

Description of Hydration Water in Protein (Green Fluorescent Protein) Solution

(2016) Stefania Perticaroli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Membrane Binding of HIV-1 Matrix Protein: Dependence on Bilayer Composition and Protein Lipidation

(2016) Marilia Barros et al.   JOURNAL OF VIROLOGY

Subnanometer Structure of an Asymmetric Model Membrane: Interleaflet Coupling Influences Domain Properties

(2016) Frederick A. Heberle et al.   LANGMUIR

QM/MM free energy simulations: recent progress and challenges

(2016) Xiya Lu et al.   MOLECULAR SIMULATION

Investigation of the micro- and nano-scale architecture of cellulose hydrogels with plant cell wall polysaccharides: A combined USANS/SANS study

(2016) Marta Martínez-Sanz et al.   POLYMER

Neutron structures of theHelicobacter pylori5′-methylthioadenosine nucleosidase highlight proton sharing and protonation states

(2016) Michael T. Banco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hierarchical architecture of bacterial cellulose and composite plant cell wall polysaccharide hydrogels using small angle neutron scattering

(2016) Marta Martínez-Sanz et al.   Soft Matter

Cryo-Electron Tomography: Can it Reveal the Molecular Sociology of Cells in Atomic Detail?

(2016) Martin Beck et al.   TRENDS IN CELL BIOLOGY

Direct visualization of a Fe(IV)–OH intermediate in a heme enzyme

(2016) Hanna Kwon et al.   Nature Communications

High protein flexibility and reduced hydration water dynamics are key pressure adaptive strategies in prokaryotes

(2016) N. Martinez et al.   Scientific Reports

Macromolecular structure phasing by neutron anomalous diffraction

(2016) Maxime G. Cuypers et al.   Scientific Reports

Revealing the Dynamics of Thylakoid Membranes in Living Cyanobacterial Cells

(2016) Laura-Roxana Stingaciu et al.   Scientific Reports

Neutron structure of human carbonic anhydrase II in complex with methazolamide: mapping the solvent and hydrogen-bonding patterns of an effective clinical drug

(2016) Mayank Aggarwal et al.   IUCrJ

High-resolution neutron and X-ray diffraction room-temperature studies of an H-FABP–oleic acid complex: study of the internal water cluster and ligand binding by a transferred multipolar electron-density distribution

(2016) E. I. Howard et al.   IUCrJ

Atomistic modelling of scattering data in the Collaborative Computational Project for Small Angle Scattering (CCP-SAS)

(2016) Stephen J. Perkins et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Determination of functional collective motions in a protein at atomic resolution using coherent neutron scattering

(2016) L. Hong et al.   Science Advances

Water-soluble photopolymerizable chitosan hydrogels for biofabrication via two-photon polymerization

(2015) Olga Kufelt et al.   Acta Biomaterialia

Neutron Crystallographic Studies Reveal Hydrogen Bond and Water-Mediated Interactions between a Carbohydrate-Binding Module and Its Bound Carbohydrate Ligand

(2015) S. Zoë Fisher et al.   BIOCHEMISTRY

Evidence for differential interaction mechanism of plant cell wall matrix polysaccharides in hierarchically-structured bacterial cellulose

(2015) Marta Martínez-Sanz et al.   CELLULOSE

Quantum Mechanics/Molecular Mechanics Modeling of Enzymatic Processes: Caveats and Breakthroughs

(2015) Matthew G. Quesne et al.   CHEMISTRY-A EUROPEAN JOURNAL

Molecular dynamics simulations of large macromolecular complexes

(2015) Juan R Perilla et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Molecular adaptation and salt stress response of Halobacterium salinarum cells revealed by neutron spectroscopy

(2015) Pierre Vauclare et al.   EXTREMOPHILES

Neutron Crystal Structure of RAS GTPase Puts in Question the Protonation State of the GTP γ-Phosphate

(2015) Ryan Knihtila et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Affordable uniform isotope labeling with 2H, 13C and 15N in insect cells

(2015) Agnieszka Sitarska et al.   JOURNAL OF BIOMOLECULAR NMR

An economic approach to efficient isotope labeling in insect cells using homemade 15N-, 13C- and 2H-labeled yeast extracts

(2015) Christian Opitz et al.   JOURNAL OF BIOMOLECULAR NMR

Efficient segmental isotope labeling of multi-domain proteins using Sortase A

(2015) Lee Freiburger et al.   JOURNAL OF BIOMOLECULAR NMR

Is It Possible To Obtain Coupled Cluster Quality Energies at near Density Functional Theory Cost? Domain-Based Local Pair Natural Orbital Coupled Cluster vs Modern Density Functional Theory

(2015) Dimitrios G. Liakos et al.   Journal of Chemical Theory and Computation

Protonation State and Hydration of Bisphosphonate Bound to Farnesyl Pyrophosphate Synthase

(2015) Takeshi Yokoyama et al.   JOURNAL OF MEDICINAL CHEMISTRY

Influence of Pressure and Crowding on the Sub-Nanosecond Dynamics of Globular Proteins

(2015) M. Erlkamp et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Mechanical Properties of Nanoscopic Lipid Domains

(2015) Jonathan D. Nickels et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Insights into the Proton Transfer Mechanism of a Bilin Reductase PcyA Following Neutron Crystallography

(2015) Masaki Unno et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Influence of Charge Density and Ionic Strength on the Aggregation Process of Cellulose Nanocrystals in Aqueous Suspension, as Revealed by Small-Angle Neutron Scattering

(2015) Fanch Cherhal et al.   LANGMUIR

Controlling Internal Organization of Multilayer Poly(methacrylic acid) Hydrogels with Polymer Molecular Weight

(2015) Veronika Kozlovskaya et al.   MACROMOLECULES

Membrane association of the PTEN tumor suppressor: Neutron scattering and MD simulations reveal the structure of protein–membrane complexes

(2015) Hirsh Nanda et al.   METHODS

Intrinsically disordered proteins in cellular signalling and regulation

(2015) Peter E. Wright et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Motional displacements in proteins: The origin of wave-vector-dependent values

(2015) Derya Vural et al.   PHYSICAL REVIEW E

Quantum effects in the dynamics of deeply supercooled water

(2015) A. L. Agapov et al.   PHYSICAL REVIEW E

Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography

(2015) Qun Wan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of pressure on the dynamics of an oligomeric protein from deep-sea hyperthermophile

(2015) Utsab R. Shrestha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polymers with upper critical solution temperature behavior in alcohol/water solvent mixtures

(2015) Qilu Zhang et al.   PROGRESS IN POLYMER SCIENCE

Solving the mystery of the internal structure of casein micelles

(2015) B. Ingham et al.   Soft Matter

Anomalous and anisotropic nanoscale diffusion of hydration water molecules in fluid lipid membranes

(2015) Laura Toppozini et al.   Soft Matter

How cryo-EM is revolutionizing structural biology

(2015) Xiao-chen Bai et al.   TRENDS IN BIOCHEMICAL SCIENCES

Translational diffusion of hydration water correlates with functional motions in folded and intrinsically disordered proteins

(2015) Giorgio Schirò et al.   Nature Communications

Coarse-grained molecular dynamics studies of the translocation mechanism of polyarginines across asymmetric membrane under tension

(2015) XiaoCong He et al.   Scientific Reports

How mobile are protons in the structure of dental glass ionomer cements?

(2015) Ana R. Benetti et al.   Scientific Reports

Protein secondary-structure description with a coarse-grained model

(2015) Gerald R. Kneller et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Memprot: a program to model the detergent corona around a membrane protein based on SEC–SAXS data

(2015) Javier Pérez et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Cholesterol oxidase: ultrahigh-resolution crystal structure and multipolar atom model-based analysis

(2015) Bartosz Zarychta et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystal structure refinement withSHELXL

(2015) George M. Sheldrick   Acta Crystallographica Section C-Structural Chemistry

The Macromolecular Neutron Diffractometer MaNDi at the Spallation Neutron Source

(2015) Leighton Coates et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

"Newton's cradle" proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography

(2015) A. Nakamura et al.   Science Advances

Functional Dynamics of Deuterated β2-Adrenergic Receptor in Lipid Bilayers Revealed by NMR Spectroscopy

(2014) Yutaka Kofuku et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Zooming in on disordered systems: Neutron reflection studies of proteins associated with fluid membranes

(2014) Frank Heinrich et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Protein aggregation and its impact on product quality

(2014) Christopher J Roberts   CURRENT OPINION IN BIOTECHNOLOGY

Marvels of enzyme catalysis at true atomic resolution: distortions, bond elongations, hidden flips, protonation states and atom identities

(2014) Piotr Neumann et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structural Features of Membrane-bound Glucocerebrosidase and α-Synuclein Probed by Neutron Reflectometry and Fluorescence Spectroscopy

(2014) Thai Leong Yap et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myristoylation Restricts Orientation of the GRASP Domain on Membranes and Promotes Membrane Tethering

(2014) Frank Heinrich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrolysis of DFP and the Nerve Agent (S)-Sarin by DFPase Proceeds along Two Different Reaction Pathways: Implications for Engineering Bioscavengers

(2014) Troy Wymore et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Temperature-Dependent Dynamics of Dry and Hydrated β-Casein Studied by Quasielastic Neutron Scattering

(2014) Gurpreet K Dhindsa et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Structure and Stability of Phospholipid Bilayers Hydrated by a Room-Temperature Ionic Liquid/Water Solution: A Neutron Reflectometry Study

(2014) Antonio Benedetto et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Direct Evidence of Conformational Changes Associated with Voltage Gating in a Voltage Sensor Protein by Time-Resolved X-ray/Neutron Interferometry

(2014) Andrey Y. Tronin et al.   LANGMUIR

Facile fabrication of novel pH-sensitive poly(aspartic acid) hydrogel by crosslinking nanofibers

(2014) Caidan Zhang et al.   MATERIALS LETTERS

Smart hybrid materials by conjugation of responsive polymers to biomacromolecules

(2014) Isidro Cobo et al.   NATURE MATERIALS

de Gennes Narrowing Describes the Relative Motion of Protein Domains

(2014) Liang Hong et al.   PHYSICAL REVIEW LETTERS

Production and Analysis of Perdeuterated Lipids from Pichia pastoris Cells

(2014) Alexis de Ghellinck et al.   PLoS One

Anomalously large isotope effect in the glass transition of water

(2014) Catalin Gainaru et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutron cryo-crystallography captures the protonation state of ferryl heme in a peroxidase

(2014) C. M. Casadei et al.   SCIENCE

Nanosecond lipid dynamics in membranes containing cholesterol

(2014) Clare L. Armstrong et al.   Soft Matter

Nonequilibrium water dynamics in the rhizosphere: How mucilage affects water flow in soils

(2014) Eva Kroener et al.   WATER RESOURCES RESEARCH

Reconstitution of a nanomachine driving the assembly of proteins into bacterial outer membranes

(2014) Hsin-Hui Shen et al.   Nature Communications

Multi-lamellar organization of fully deuterated lipid extracts of yeast membranes

(2014) Yuri Gerelli et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Neutron structure of the cyclic glucose-bound xylose isomerase E186Q mutant

(2014) Parthapratim Munshi et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Stealth carriers for low-resolution structure determination of membrane proteins in solution

(2014) Selma Maric et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein

(2014) Melina Haupt et al.   IUCrJ

Integration of neutron time-of-flight single-crystal Bragg peaks in reciprocal space

(2014) Arthur J. Schultz et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

The IMAGINE instrument: first neutron protein structure and new capabilities for neutron macromolecular crystallography

(2013) Flora Meilleur et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Hydrogen Tunneling Links Protein Dynamics to Enzyme Catalysis

(2013) Judith P. Klinman et al.   Annual Review of Biochemistry

Deuterated Polymers for Probing Phase Separation Using Infrared Microspectroscopy

(2013) Robert A. Russell et al.   BIOMACROMOLECULES

Coherent Neutron Scattering and Collective Dynamics in the Protein, GFP

(2013) Jonathan D. Nickels et al.   BIOPHYSICAL JOURNAL

The effect of deuteration on the structure of bacterial cellulose

(2013) Garima Bali et al.   CARBOHYDRATE RESEARCH

Controlled incorporation of deuterium into bacterial cellulose

(2013) Junhong He et al.   CELLULOSE

Editorial on the Topical Issue “Neutron Biological Physics”

(2013) Giovanna Fragneto et al.   EUROPEAN PHYSICAL JOURNAL E

Small angle neutron scattering for the study of solubilised membrane proteins

(2013) Cécile Breyton et al.   EUROPEAN PHYSICAL JOURNAL E

Common processes drive the thermochemical pretreatment of lignocellulosic biomass

(2013) Paul Langan et al.   GREEN CHEMISTRY

Dynamic neutron scattering from conformational dynamics. I. Theory and Markov models

(2013) Benjamin Lindner et al.   JOURNAL OF CHEMICAL PHYSICS

Model-free simulation approach to molecular diffusion tensors

(2013) Guillaume Chevrot et al.   JOURNAL OF CHEMICAL PHYSICS

Motional heterogeneity in human acetylcholinesterase revealed by a non-Gaussian model for elastic incoherent neutron scattering

(2013) Judith Peters et al.   JOURNAL OF CHEMICAL PHYSICS

Hybrid and Nonhybrid Lipids Exert Common Effects on Membrane Raft Size and Morphology

(2013) Frederick A. Heberle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Water Dynamics in Neural Tissue

(2013) Francesca Natali et al.   JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN

Evolutionary biochemistry: revealing the historical and physical causes of protein properties

(2013) Michael J. Harms et al.   NATURE REVIEWS GENETICS

Role of Quantum Effects in the Glass Transition

(2013) V. N. Novikov et al.   PHYSICAL REVIEW LETTERS

Neutron imaging reveals internal plant water dynamics

(2013) Jeffrey M. Warren et al.   PLANT AND SOIL

Constant pH molecular dynamics of proteins in explicit solvent with proton tautomerism

(2013) Garrett B. Goh et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Secondary structure and rigidity in model proteins

(2013) Stefania Perticaroli et al.   Soft Matter

Eppur Si Muove! The 2013 Nobel Prize in Chemistry

(2013) Jeremy C. Smith et al.   STRUCTURE

Glutaraldehyde in bio-catalysts design: a useful crosslinker and a versatile tool in enzyme immobilization

(2013) Oveimar Barbosa et al.   RSC Advances

Refinement of macromolecular structures against neutron data withSHELXL2013

(2013) Tim Gruene et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Protein Surface and Core Dynamics Show Concerted Hydration-Dependent Activation

(2012) Kathleen Wood et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Near-Atomic Resolution Neutron Crystallography on PerdeuteratedPyrococcus furiosusRubredoxin: Implication of Hydronium Ions and Protonation State Equilibria in Redox Changes

(2012) M. G. Cuypers et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Interaction of Tau Protein with Model Lipid Membranes Induces Tau Structural Compaction and Membrane Disruption

(2012) Emmalee M. Jones et al.   BIOCHEMISTRY

Dynamics of Protein and its Hydration Water: Neutron Scattering Studies on Fully Deuterated GFP

(2012) Jonathan D. Nickels et al.   BIOPHYSICAL JOURNAL

Coupled Flexibility Change in Cytochrome P450cam Substrate Binding Determined by Neutron Scattering, NMR, and Molecular Dynamics Simulation

(2012) Yinglong Miao et al.   BIOPHYSICAL JOURNAL

Depth of α-Synuclein in a Bilayer Determined by Fluorescence, Neutron Reflectometry, and Computation

(2012) Candace M. Pfefferkorn et al.   BIOPHYSICAL JOURNAL

Sassena — X-ray and neutron scattering calculated from molecular dynamics trajectories using massively parallel computers

(2012) Benjamin Lindner et al.   COMPUTER PHYSICS COMMUNICATIONS

Neutron and X-ray Crystal Structures of a Perdeuterated Enzyme Inhibitor Complex Reveal the Catalytic Proton Network of the Toho-1 β-Lactamase for the Acylation Reaction

(2012) Stephen J. Tomanicek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impact of anisotropic atomic motions in proteins on powder-averaged incoherent neutron scattering intensities

(2012) Gerald R. Kneller et al.   JOURNAL OF CHEMICAL PHYSICS

nMoldyn 3: Using task farming for a parallel spectroscopy-oriented analysis of molecular dynamics simulations

(2012) Konrad Hinsen et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Small-Angle Neutron Scattering Study of Protein Crowding in Liquid and Solid Phases: Lysozyme in Aqueous Solution, Frozen Solution, and Carbohydrate Powders

(2012) Joseph E. Curtis et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Derivation of Mean-Square Displacements for Protein Dynamics from Elastic Incoherent Neutron Scattering

(2012) Zheng Yi et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Apparent Decoupling of the Dynamics of a Protein from the Dynamics of its Aqueous Solvent

(2012) Xiang-qiang Chu et al.   Journal of Physical Chemistry Letters

Membrane association of the PTEN tumor suppressor: Electrostatic interaction with phosphatidylserine-containing bilayers and regulatory role of the C-terminal tail

(2012) Siddharth S. Shenoy et al.   JOURNAL OF STRUCTURAL BIOLOGY

Membrane bending by protein–protein crowding

(2012) Jeanne C. Stachowiak et al.   NATURE CELL BIOLOGY

Water–protein dynamic coupling and new opportunities for probing it at low to physiological temperatures in aqueous solutions

(2012) Eugene Mamontov et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Lipid Bilayers and Membrane Dynamics: Insight into Thickness Fluctuations

(2012) Andrea C. Woodka et al.   PHYSICAL REVIEW LETTERS

Granger Causality Analysis of Steady-State Electroencephalographic Signals during Propofol-Induced Anaesthesia

(2012) Adam B. Barrett et al.   PLoS One

Membrane Association of the PTEN Tumor Suppressor: Molecular Details of the Protein-Membrane Complex from SPR Binding Studies and Neutron Reflection

(2012) Siddharth Shenoy et al.   PLoS One

Direct observation of hydrogen atom dynamics and interactions by ultrahigh resolution neutron protein crystallography

(2012) J. C.- H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Putting the Pieces Together: Integrative Modeling Platform Software for Structure Determination of Macromolecular Assemblies

(2012) Daniel Russel et al.   PLOS BIOLOGY

Rapid visualization of hydrogen positions in protein neutron crystallographic structures

(2011) Parthapratim Munshi et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Identification of the Elusive Hydronium Ion Exchanging Roles with a Proton in an Enzyme at Lower pH Values

(2011) Andrey Y. Kovalevsky et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluid phase lipid areas and bilayer thicknesses of commonly used phosphatidylcholines as a function of temperature

(2011) Norbert Kučerka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Noninvasive Neutron Scattering Measurements Reveal Slower Cholesterol Transport in Model Lipid Membranes

(2011) S. Garg et al.   BIOPHYSICAL JOURNAL

SASSIE: A program to study intrinsically disordered biological molecules and macromolecular ensembles using experimental scattering restraints

(2011) Joseph E. Curtis et al.   COMPUTER PHYSICS COMMUNICATIONS

Continuous distribution model for the investigation of complex molecular architectures near interfaces with scattering techniques

(2011) Prabhanshu Shekhar et al.   JOURNAL OF APPLIED PHYSICS

DFTB3: Extension of the Self-Consistent-Charge Density-Functional Tight-Binding Method (SCC-DFTB)

(2011) Michael Gaus et al.   Journal of Chemical Theory and Computation

Surveying implicit solvent models for estimating small molecule absolute hydration free energies

(2011) Jennifer L. Knight et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

The Phenix software for automated determination of macromolecular structures

(2011) Paul D. Adams et al.   METHODS

Physics of life: The dawn of quantum biology

(2011) Philip Ball   NATURE

Three-dimensional visualization and quantification of water content in the rhizosphere

(2011) Ahmad B. Moradi et al.   NEW PHYTOLOGIST

Solution structure of the ESCRT-I complex by small-angle X-ray scattering, EPR, and FRET spectroscopy

(2011) E. Boura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein self-diffusion in crowded solutions

(2011) F. Roosen-Runge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Grand Challenge in Biology

(2011) B. Alberts   SCIENCE

Cell Membranes: The Lipid Perspective

(2011) Ünal Coskun et al.   STRUCTURE

Joint X-ray and neutron refinement withphenix.refine

(2010) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Activation of Nanoscale Allosteric Protein Domain Motion Revealed by Neutron Spin Echo Spectroscopy

(2010) Bela Farago et al.   BIOPHYSICAL JOURNAL

Neutron Reflectometry Study of the Conformation of HIV Nef Bound to Lipid Membranes

(2010) Michael S. Kent et al.   BIOPHYSICAL JOURNAL

Electrostatic Interactions and Binding Orientation of HIV-1 Matrix Studied by Neutron Reflectivity

(2010) Hirsh Nanda et al.   BIOPHYSICAL JOURNAL

Microfluidic biolector-microfluidic bioprocess control in microtiter plates

(2010) Matthias Funke et al.   BIOTECHNOLOGY AND BIOENGINEERING

HIV-1 Gag Extension: Conformational Changes Require Simultaneous Interaction with Membrane and Nucleic Acid

(2010) Siddhartha A.K. Datta et al.   JOURNAL OF MOLECULAR BIOLOGY

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

(2010) Jeffery B. Klauda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Electrostatic Swelling and Conformational Variation Observed in High-Generation Polyelectrolyte Dendrimers

(2010) Yun Liu et al.   Journal of Physical Chemistry Letters

Bioprocess Control in Microscale: Scalable Fermentations in Disposable and User-Friendly Microfluidic Systems

(2010) Matthias Funke et al.   Microbial Cell Factories

Neutron computed tomography of rat lungs

(2010) R W Metzke et al.   PHYSICS IN MEDICINE AND BIOLOGY

Dynamics of soil water content in the rhizosphere

(2010) Andrea Carminati et al.   PLANT AND SOIL

Multidomain assembled states of Hck tyrosine kinase in solution

(2010) S. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generalized X-ray and neutron crystallographic analysis: more accurate and complete structures for biological macromolecules

(2009) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Neutron Structure of Human Carbonic Anhydrase II: Implications for Proton Transfer

(2009) S. Zoë Fisher et al.   BIOCHEMISTRY

Using polarization analysis to separate the coherent and incoherent scattering from protein samples

(2009) Ana M. Gaspar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Structure of Functional Staphylococcus aureus α-Hemolysin Channels in Tethered Bilayer Lipid Membranes

(2009) Duncan J. McGillivray et al.   BIOPHYSICAL JOURNAL

Production of recombinant proteins by microbes and higher organisms

(2009) Arnold L. Demain et al.   BIOTECHNOLOGY ADVANCES

Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin

(2009) Aurélien Bancaud et al.   EMBO JOURNAL

Production of isotopically labeled heterologous proteins in non-E. coli prokaryotic and eukaryotic cells

(2009) Hideo Takahashi et al.   JOURNAL OF BIOMOLECULAR NMR

Elucidation of the Phosphate Binding Mode of DING Proteins Revealed by Subangstrom X-ray Crystallography

(2009) Dorothee Liebschner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Neutrons for biologists: a beginner's guide, or why you should consider using neutrons

(2009) J. H. Lakey   Journal of the Royal Society Interface

A unified model of protein dynamics

(2009) H. Frauenfelder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An evaluation review of the prediction of protonation states in proteinsversuscrystallographic experiment†

(2009) Stuart J. Fisher et al.   Crystallography Reviews

Neutron macromolecular crystallography

(2009) M.P. Blakeley   Crystallography Reviews

An investigation into structural changes due to deuteration

(2008) S. J. Fisher et al.   ACTA CRYSTALLOGRAPHICA SECTION A

Hydrogen Location in Stages of an Enzyme-Catalyzed Reaction: Time-of-Flight Neutron Structure ofd-Xylose Isomerase with Boundd-Xylulose†‡

(2008) Andrey Y. Kovalevsky et al.   BIOCHEMISTRY

Soluble Amyloid β-Oligomers Affect Dielectric Membrane Properties by Bilayer Insertion and Domain Formation: Implications for Cell Toxicity

(2008) Gintaras Valincius et al.   BIOPHYSICAL JOURNAL

Protein Dynamics and Stability: The Distribution of Atomic Fluctuations in Thermophilic and Mesophilic Dihydrofolate Reductase Derived Using Elastic Incoherent Neutron Scattering

(2008) Lars Meinhold et al.   BIOPHYSICAL JOURNAL

Selective deuteration of tryptophan and methionine residues in maltose binding protein: a model system for neutron scattering

(2008) Valerie Laux et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Influence of Hydration on Protein Dynamics: Combining Dielectric and Neutron Scattering Spectroscopy Data

(2008) S. Khodadadi et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Protein production and purification

(2008) Susanne Gräslund et al.   NATURE METHODS

A practical guide to single-molecule FRET

(2008) Rahul Roy et al.   NATURE METHODS

Development of data processing software for a new TOF single crystal neutron diffractometer at J-PARC

(2008) Takashi Ohhara et al.   NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT

Quantitative Imaging of Infiltration, Root Growth, and Root Water Uptake via Neutron Radiography

(2008) Sascha E. Oswald et al.   VADOSE ZONE JOURNAL

Relaxation dynamics of lysozyme in solution under pressure: Combining molecular dynamics simulations and quasielastic neutron scattering

(2007) V. Calandrini et al.   CHEMICAL PHYSICS

Membrane Fusogenic Activity of the Alzheimer's Peptide Aβ(1–42) Demonstrated by Small-Angle Neutron Scattering

(2007) Silvia Dante et al.   JOURNAL OF MOLECULAR BIOLOGY