A Novel Systems Pharmacology Method to Investigate Molecular Mechanisms of Scutellaria barbata D. Don for Non-small Cell Lung Cancer
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A Novel Systems Pharmacology Method to Investigate Molecular Mechanisms of Scutellaria barbata D. Don for Non-small Cell Lung Cancer
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-12-17
DOI
10.3389/fphar.2018.01473
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Metformin Inhibits Prostate Cancer Progression by Targeting Tumor-Associated Inflammatory Infiltration
- (2018) Qiuli Liu et al. CLINICAL CANCER RESEARCH
- Inhibition effects of total flavonoids from Sculellaria barbata D. Don on human breast carcinoma bone metastasis via downregulating PTHrP pathway
- (2018) Xiao Zheng et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Luteolin Inhibits Tumorigenesis and Induces Apoptosis of Non-Small Cell Lung Cancer Cells via Regulation of MicroRNA-34a-5p
- (2018) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Epoxymicheliolide, a novelguaiane-type sesquiterpene lactone, inhibits NF‑κB/COX‑2 signaling pathways by targeting leucine�281 and leucine�25 in IKKβ in renal cell carcinoma
- (2018) Jiabin Zhu et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Systematic investigation of the Erigeron breviscapus mechanism for treating cerebrovascular disease
- (2018) Jiangmei Wang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Enhanced anticancer effects of Scutellaria barbata D. Don in combination with traditional Chinese medicine components on non-small cell lung cancer cells
- (2018) Qian Wang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Selective targeting of antiapoptotic BCL-2 proteins in cancer
- (2018) Ahmet Can Timucin et al. MEDICINAL RESEARCH REVIEWS
- Selective Anti-tumor Activity of wogonin targeting the Warburg Effect through stablizing p53
- (2018) Yikai Zhao et al. PHARMACOLOGICAL RESEARCH
- Deciphering the multicomponent synergy mechanism from a systems pharmacology perspective: Application to Gualou Xiebai Decoction for coronary heart disease
- (2018) Yang Yang et al. Journal of Functional Foods
- Pharmacologic inhibition of protein phosphatase-2A achieves durable immune-mediated antitumor activity when combined with PD-1 blockade
- (2018) Winson S. Ho et al. Nature Communications
- Baicalein and baicalin inhibit colon cancer using two distinct fashions of apoptosis and senescence
- (2018) Jie Dou et al. Oncotarget
- β-Sitosterol targets Trx/Trx1 reductase to induce apoptosis in A549 cells via ROS mediated mitochondrial dysregulation and p53 activation
- (2018) Tamilselvam Rajavel et al. Scientific Reports
- A De Novo Mouse Model of C11orf95-RELA Fusion-Driven Ependymoma Identifies Driver Functions in Addition to NF-κB
- (2018) Tatsuya Ozawa et al. Cell Reports
- Scutellarin Increases Cisplatin-Induced Apoptosis and Autophagy to Overcome Cisplatin Resistance in Non-small Cell Lung Cancer via ERK/p53 and c-met/AKT Signaling Pathways
- (2018) Chao-Yue Sun et al. Frontiers in Pharmacology
- Inhibition of NF-κB Signaling Reduces the Stemness Characteristics of Lung Cancer Stem Cells
- (2018) Norashikin Zakaria et al. Frontiers in Oncology
- Tim-4 promotes the growth of colorectal cancer by activating angiogenesis and recruiting tumor-associated macrophages via the PI3K/AKT/mTOR signaling pathway
- (2018) Xiao Tan et al. CANCER LETTERS
- High Platelet Levels Attenuate the Efficacy of Platinum-Based Treatment in Non-Small Cell Lung Cancer
- (2018) Zhangfei Wang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- MKRN2 inhibits migration and invasion of non-small-cell lung cancer by negatively regulating the PI3K/Akt pathway
- (2018) Jun Jiang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- A natural flavonoid lawsonaringenin induces cell cycle arrest and apoptosis in HT-29 colorectal cancer cells by targeting multiple signalling pathways
- (2018) Areeba Anwar et al. MOLECULAR BIOLOGY REPORTS
- Lung Cancers: Molecular Characterization, Clonal Heterogeneity and Evolution, and Cancer Stem Cells
- (2018) Ugo Testa et al. Cancers
- Anti-tumor effect of Scutellaria barbata D. Don extracts on ovarian cancer and its phytochemicals characterisation
- (2017) Lin Zhang et al. JOURNAL OF ETHNOPHARMACOLOGY
- MCL Plays an Anti-Inflammatory Role in Mycobacterium tuberculosis-Induced Immune Response by Inhibiting NF-κB and NLRP3 Inflammasome Activation
- (2017) Qingwen Zhang et al. MEDIATORS OF INFLAMMATION
- Ethyl acetate extract from Asparagus cochinchinensis exerts anti-inflammatory effects in LPS-stimulated RAW264.7 macrophage cells by regulating COX-2/iNOS, inflammatory cytokine expression, MAP kinase pathways, the cell cycle and anti-oxidant activity
- (2017) Hyun Ah Lee et al. Molecular Medicine Reports
- In silico-based screen synergistic drug combinations from herb medicines: a case using Cistanche tubulosa
- (2017) Jianling Liu et al. Scientific Reports
- Systems Pharmacology Uncovers the Multiple Mechanisms of Xijiao Dihuang Decoction for the Treatment of Viral Hemorrhagic Fever
- (2016) Jianling Liu et al. Evidence-based Complementary and Alternative Medicine
- PI3Kγ is a molecular switch that controls immune suppression
- (2016) Megan M. Kaneda et al. NATURE
- KEGG: new perspectives on genomes, pathways, diseases and drugs
- (2016) Minoru Kanehisa et al. NUCLEIC ACIDS RESEARCH
- Ursolic acid sensitizes radioresistant NSCLC cells expressing HIF-1α through reducing endogenous GSH and inhibiting HIF-1α
- (2016) Bing Song et al. Oncology Letters
- When the East meets the West: the future of traditional Chinese medicine in the 21st century
- (2015) Jane Qiu National Science Review
- Systems pharmacology-based approach for dissecting the addition and subtraction theory of traditional Chinese medicine: An example using Xiao-Chaihu-Decoction and Da-Chaihu-Decoction
- (2014) Bohui Li et al. COMPUTERS IN BIOLOGY AND MEDICINE
- System-level multi-target drug discovery from natural products with applications to cardiovascular diseases
- (2014) Chunli Zheng et al. MOLECULAR DIVERSITY
- Systems Pharmacology Dissection of Multi-Scale Mechanisms of Action for Herbal Medicines in Stroke Treatment and Prevention
- (2014) Jingxiao Zhang et al. PLoS One
- TCMSP: a database of systems pharmacology for drug discovery from herbal medicines
- (2014) Jinlong Ru et al. Journal of Cheminformatics
- Anti-angiogenic effect of the total flavonoids in Scutellaria barbata D. Don
- (2013) Zhi-Jun Dai et al. BMC Complementary and Alternative Medicine
- Systems pharmacology in drug discovery and therapeutic insight for herbal medicines
- (2013) Chao Huang et al. BRIEFINGS IN BIOINFORMATICS
- Systems approaches and polypharmacology for drug discovery from herbal medicines: An example using licorice
- (2013) Hui Liu et al. JOURNAL OF ETHNOPHARMACOLOGY
- Barbigerone, an isoflavone, inhibits tumor angiogenesis and human non-small-cell lung cancer xenografts growth through VEGFR2 signaling pathways
- (2012) Xiuxia Li et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Systems pharmacology uncovers Janus functions of botanical drugs: activation of host defense system and inhibition of influenza virus replication
- (2012) Xia Wang et al. Integrative Biology
- A Novel Chemometric Method for the Prediction of Human Oral Bioavailability
- (2012) Xue Xu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A Systematic Prediction of Multiple Drug-Target Interactions from Chemical, Genomic, and Pharmacological Data
- (2012) Hua Yu et al. PLoS One
- The evaluation and implementation of direct analysis in real time quadrupole time-of-flight tandem mass spectrometry for characterization and quantification of geniposide in Re Du Ning Injections
- (2012) Yan-Jing Li et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery
- (2011) F. Zhu et al. NUCLEIC ACIDS RESEARCH
- Drug-target interaction prediction from chemical, genomic and pharmacological data in an integrated framework
- (2010) Y. Yamanishi et al. BIOINFORMATICS
- The Comparative Toxicogenomics Database: update 2011
- (2010) A. P. Davis et al. NUCLEIC ACIDS RESEARCH
- Network analyses in systems pharmacology
- (2009) S. I. Berger et al. BIOINFORMATICS
- Two novel neo-clerodane diterpenoids from Scutellaria barbata
- (2009) Hanna Lee et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Network pharmacology: the next paradigm in drug discovery
- (2008) Andrew L Hopkins Nature Chemical Biology
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started