Systems Pharmacology Uncovers the Multiple Mechanisms of Xijiao Dihuang Decoction for the Treatment of Viral Hemorrhagic Fever

Radiosensitization of non-small cell lung cancer by kaempferol

(2015) WEI-TING KUO et al.   ONCOLOGY REPORTS

Large-scale Direct Targeting for Drug Repositioning and Discovery

(2015) Chunli Zheng et al.   Scientific Reports

Effects of total glucosides of paeony on immune regulatory toll-like receptors TLR2 and 4 in the kidney from diabetic rats

(2014) Xing-xin Xu et al.   PHYTOMEDICINE

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

(2014) Jinlong Ru et al.   Journal of Cheminformatics

Systems pharmacology in drug discovery and therapeutic insight for herbal medicines

(2013) Chao Huang et al.   BRIEFINGS IN BIOINFORMATICS

Systems approaches and polypharmacology for drug discovery from herbal medicines: An example using licorice

(2013) Hui Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Incorporation of β-sitosterol into the membrane increases resistance to oxidative stress and lipid peroxidation via estrogen receptor-mediated PI3K/GSK3β signaling

(2012) Chun Shi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Protective Effects of Natural Products on Blood-Brain Barrier Breakdown

(2012) A. Kam et al.   CURRENT MEDICINAL CHEMISTRY

Systems pharmacology uncovers Janus functions of botanical drugs: activation of host defense system and inhibition of influenza virus replication

(2012) Xia Wang et al.   Integrative Biology

A Novel Chemometric Method for the Prediction of Human Oral Bioavailability

(2012) Xue Xu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Network pharmacology-based prediction of the active ingredients and potential targets of Chinese herbal Radix Curcumae formula for application to cardiovascular disease

(2012) Weiyang Tao et al.   JOURNAL OF ETHNOPHARMACOLOGY

A Systematic Prediction of Multiple Drug-Target Interactions from Chemical, Genomic, and Pharmacological Data

(2012) Hua Yu et al.   PLoS One

A System-Level Investigation into the Mechanisms of Chinese Traditional Medicine: Compound Danshen Formula for Cardiovascular Disease Treatment

(2012) Xiuxiu Li et al.   PLoS One

Inhibitory effect of astragalin on expression of lipopolysaccharide-induced inflammatory mediators through NF-κB in macrophages

(2011) Mi-Sun Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

Phosphoinositide-3 Kinase-Akt Pathway Controls Cellular Entry of Ebola Virus

(2011) Mohammad F. Saeed et al.   PLoS Pathogens

Identification of Direct Protein Targets of Small Molecules

(2010) Brett Lomenick et al.   ACS Chemical Biology

Kaempferol inhibits UVB-induced COX-2 expression by suppressing Src kinase activity

(2010) Kyung Mi Lee et al.   BIOCHEMICAL PHARMACOLOGY

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

Prothrombin activation on the activated platelet surface optimizes expression of procoagulant activity

(2010) J. P. Wood et al.   BLOOD

DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs

(2010) C. Knox et al.   NUCLEIC ACIDS RESEARCH

Sparse Partial Least Squares Classification for High Dimensional Data

(2010) Dongjun Chung et al.   Statistical Applications in Genetics and Molecular Biology

Paeoniflorin Inhibits Systemic Inflammation and Improves Survival in Experimental Sepsis

(2009) Wang-Lin Jiang et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Network analyses in systems pharmacology

(2009) S. I. Berger et al.   BIOINFORMATICS

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Treatment of severe aplastic anemia by immunosuppressor anti-lymphocyte globulin/anti-thymus globulin as the chief medicine in combination with Chinese drugs

(2009) Bing-rong Zheng et al.   Chinese Journal of Integrative Medicine

Kaempferol induces apoptosis in two different cell lines via Akt inactivation, Bax and SIRT3 activation, and mitochondrial dysfunction

(2009) Gabriella Marfe et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

β-Sitosterol exhibits anti-inflammatory activity in human aortic endothelial cells

(2009) Stella Loizou et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Paeonol from Paeonia suffruticosa prevents TNF-α-induced monocytic cell adhesion to rat aortic endothelial cells by suppression of VCAM-1 expression

(2009) L.L. Pan et al.   PHYTOMEDICINE

Anti-inflammatory and antinociceptive activities A of eugenol essential oil in experimental animal models

(2009) Apparecido N. Daniel et al.   Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

Highly pathogenic RNA viral infections: Challenges for antiviral research

(2008) Mike Bray   ANTIVIRAL RESEARCH